| Interacting proteins: P08648 and P00533 |
Pubmed |
SVM Score :0.0 |
| Computer searching of this region of the integrin alpha 5 promoter revealed two tandemly repeated motifs , TCCTCCTCC , that had previously been implicated in the function of the epidermal growth factor receptor ( EGFR ) promoter . ^^^ |
|
| Interacting proteins: P08648 and P00533 |
Pubmed |
SVM Score :0.0 |
| Human integrin alpha 5 was transfected into the integrin alpha5 / beta1 negative intestinal epithelial cell line Caco 2 to study EGF receptor ( EGFR ) and integrin alpha5 / beta1 signaling interactions involved in epithelial cell proliferation . ^^^ In the presence of the EGFR antagonistic mAb 225 , the integrin alpha 5 transfectants and controls were significantly growth inhibited on plastic . ^^^ The reversal of mAb 225 mediated growth inhibition on fibronectin for the integrin alpha 5 transfectants correlated with activation of the EGFR , activation of MAPK , and expression of proliferating cell nuclear antigen . ^^^ Although EGFR activation occurred when either the integrin alpha 5 transfected or control cells were cultured on fibronectin , coprecipitation of the EGFR with SHC could be demonstrated only in the integrin alpha 5 transfected cells . ^^^ |
|
| Interacting proteins: P08648 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08648 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08648 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08648 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08648 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08648 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08648 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|