| Interacting proteins: P55085 and P08246 |
Pubmed |
SVM Score :0.0 |
| Mass spectrometry studies of PAR2E predicted activation of PAR 2 by trypsin through cleavage at the Arg 36 Ser37 site , no effect of thrombin , and inactivation of the receptor by plasmin , calpain and leukocyte elastase , cathepsin G , and proteinase 3 . ^^^ |
|
| Interacting proteins: P55085 and P08246 |
Pubmed |
SVM Score :0.0 |
| HLE and Cat G cleaved the peptide corresponding to the N terminus of PAR 2 with exposure of its tethered ligand . ^^^ Treatment with trypsin , an agonist for PAR 2 , and a synthetic PAR 2 agonist peptide induced intracellular Ca ( 2+ ) mobilization and rendered cells refractory to subsequent stimulation with HLE and Cat G . ^^^ The production of cytokine induced by HLE and Cat G and the PAR 2 agonist peptide was completely abolished by inhibition of phospholipase C . ^^^ |
|
| Interacting proteins: P55085 and P08246 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55085 and P08246 |
Pubmed |
SVM Score :0.0 |
| NA |
|