| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| The SRP receptor consists of two subunits , SR alpha and SR beta , both tightly associated with the ER membrane . ^^^ |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| Dendrograms constructed on the basis of Pn and Ps indicated that SRA differentiated first , followed by SRB . ^^^ |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| Here we report that the SRP receptor contains , in addition to the previously identified and sequenced 69 kD polypeptide ( alpha subunit , SR alpha ) , a 30 kD beta subunit ( SR beta ) . ^^^ One of the 30 kD proteins ( SR beta ) forms a tight complex with SR alpha in detergent solution that is stable to high salt and can be immunoprecipitated with antibodies to either SR alpha or SR beta . ^^^ The presence of SR beta was previously masked by proteolytic breakdown products of SR alpha observed by others and by the presence of another 30 kD ER membrane protein ( mp 30 ) which co purifies with SR alpha . ^^^ Mp 30 binds to SRP Sepharose directly and is present in the ER membrane in several fold molar excess of SR alpha and SR beta . ^^^ |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| Thirty four women with bulimia nervosa and 34 women without bulimarexic symptoms ( but matched for age , weight , deviance from ideal weight , and educational status ) were compared as to how liberated their attitude towards the woman ' s role in society ( = their sex role attitude , SRA ) and their actual own behavior as females ( = their sex role behavior , SRB ) were . ^^^ SRA and SRB were significantly less liberated in the bulimarexic group than in the control group . ^^^ In addition , the bulimarexic group showed a wide gap between their general attitude ( SRA ) and actual behavior ( SRB ) as to the degree of liberation . ^^^ |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| We cloned a Bacillus subtilis gene ( srb ) encoding a homologue of the mammalian signal recognition particle receptor alpha subunit ( SR alpha ) . ^^^ |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| The signal recognition particle receptor consists of two subunits of 72 kDa ( SR alpha ) and 30 kDa ( SR beta ) . ^^^ The membrane binding domain is also the major site of tight binding with SR beta , suggesting that SR beta plays a role in the membrane assembly of SR alpha . . ^^^ |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| The SR is a heterodimeric protein comprised of a 69 kD subunit ( SR alpha ) and a 30 kD subunit ( SR beta ) which are associated with the ER membrane in an unknown manner . ^^^ Molecular cloning and sequencing of a cDNA encoding SR beta revealed that SR beta is a transmembrane protein and , like SR alpha and SRP 54 , is a member of the GTPase superfamily . ^^^ SR alpha appears to be peripherally associated with the ER membrane , and we suggest that SR beta , as an integral membrane protein , mediates the membrane association of SR alpha . ^^^ |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| This complex is directed to the endoplasmic reticulum membrane as a result of its interaction with the SRP receptor , a membrane protein composed of two subunits , SR alpha and SR beta , each of which also contains a GTP binding domain . ^^^ |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| Targeting is mediated by the binding of SRP to the SRP receptor , a membrane protein comprising two different subunits , SR alpha and SR beta . ^^^ Interaction of SRP and SR alpha / SR beta causes release of the signal and the engagement of the nascent chain with the membrane bound translocation apparatus . ^^^ The transmembrane protein SR beta also contains a GTPase domain , but it is not closely related to those of SRP 54 and SR alpha . ^^^ All three proteins bind GTP specifically , and the SR alpha / SR beta complex stimulates both GTP binding to and GTP hydrolysis by SRP 54 . ^^^ |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| However , E . coli does not possess a close homologue of the integral membrane protein SR beta , which anchors SR alpha to the membrane . ^^^ |
|
| Interacting proteins: P08240 and Q9Y5M8 |
Pubmed |
SVM Score :0.0 |
| This targeting step is regulated by three G proteins , SRP 54 , SR alpha , and SR beta , which act in concert . ^^^ Here , we present the 1 . 7 A crystal structure of the SR beta GTP subunit in complex with the interaction domain of SR alpha . ^^^ |
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