| Interacting proteins: P08123 and P07585 |
Pubmed |
SVM Score :0.0 |
| We have identified complementary DNAs from eight genes including collagen alpha 1 ( 6 ) , collagen alpha 1 ( 3 ) , decorin , complement C1r , collagen alpha 1 ( 1 ) , collagen alpha 2 ( 1 ) , and two novel genes , Q 6 and Q 10 . ^^^ |
|
| Interacting proteins: P08123 and P07585 |
Pubmed |
SVM Score :0.0 |
| Transfection of human dermal fibroblasts with several extracellular matrix gene ( COL1A1 , COL1A2 , COL3A1 , COL5A2 , COL7A1 , TIMP 1 , and decorin ) promoter / reporter constructs demonstrated that anti sense Sp 1 induced reduction of extracellular matrix gene mRNA steady state levels results from transcriptional repression , consistent with the role of Sp 1 as a transcription factor . ^^^ |
|
| Interacting proteins: P08123 and P07585 |
Pubmed |
SVM Score :0.0 |
| We excluded the COL1A1 , COL1A2 , and DCN gene as major candidate genes for classic EDS , since no causal mutation in these genes was found in a number of patients who tested negative for COL5A1 and COL5A2 . . ^^^ |
|
| Interacting proteins: P08123 and P07585 |
Pubmed |
SVM Score :0.0 |
| For gene analysis , conventional and quantitative polymerase chain reactions were used for COL1A2 , COL2A1 , aggrecan , BMP 2 , biglycan , decorin , osteonectin , fibromodulin , fibronectin , matrix metalloproteinase 13 ( MMP 13 ) , and tissue inhibitor of MMP 1 . ^^^ Gene expression analysis showed a significant up regulation of COL1A2 , osteonectin , decorin , fibronectin , tissue inhibitor of MMP 1 , BMP 2 , and MMP 13 in compressed discs . ^^^ |
|
| Interacting proteins: P08123 and P07585 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08123 and P07585 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P08123 and P07585 |
Pubmed |
SVM Score :0.0 |
| NA |
|