| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.57249809 |
| Monitoring the activation state of the insulin like growth factor 1 receptor and its interaction with protein tyrosine phosphatase 1B using bioluminescence resonance energy transfer . 0.57249809^^^ |
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| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| Here we investigated the regulation of IGF IR activation and function by protein tyrosine phosphatase 1B ( PTP 1B ) . ^^^ |
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| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| Seventy two PCOS patients and 42 healthy controls were genotyped for 15 variants in the genes encoding for paraoxonase ( three variants ) , plasma cell differentiation antigen glycoprotein , human sorbin and SH 3 domain containing 1 , plasminogen activator inhibitor 1 , peroxisome proliferator activated receptor gamma 2 , protein tyrosine phosphatase 1B ( two variants ) , adiponectin ( two variants ) , IGF 1 , IGF 2 , IGF 1 receptor , and IGF 2 receptor . ^^^ |
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| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| Regulation of signaling responses from the IGF IR involves the actions of regulatory adapter proteins including RACK 1 and Grb 10 that recruit or sequester cytoplasmic proteins , and the actions of phosphatases including tyrosine PTP 1B , PTEN , and PP2A . ^^^ |
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| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| Coexpression of a mammalian tyrosine phosphatase PTP1B with betawt completely inhibited this tyrosine kinase activity in yeast and also reduced the tyrosine phosphorylation in COS cells transfected with the GFP IGF 1R . ^^^ Using both of these methods , IGF 1R kinase activity was shown to be inhibited by the protein tyrosine phosphatase , PTP1B . . ^^^ |
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| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| Finally , cells lacking IGF IR showed a much lower association between IR or IRS 1 and phosphotyrosine phosphatase 1B ( PTP1B ) and also a decreased PTP1B activity upon insulin stimulation . ^^^ |
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| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| Minimal overlapping amplified sites could be seen at 5p14 ( MLVI 2 ) , 6p12 21 . 1 ( NRASL 3 ) , 7p12 ( EGFR ) , 8q23 24 . 1 ( MYC ) , 12q21 . 1 , 15q25 ( IGF1R ) , 17q12 21 ( ERBB2 / HER2 neu ) , 19q13 . 1 ( TGFB 1 , BCL 3 , AKT 2 ) , 20p12 ( PCNA ) , 20q12 13 ( MYBL 2 , PTPN 1 ) , and Xq 25 . ^^^ |
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| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| The highest frequencies for DNA sequence copy number gains were detected for SNRPN ( 61 % ) ; GNLY ( 44 % ) ; NME 1 ( 44 % ) ; DDX 15 , ABCB 1 ( MDR ) , ATM , LAMA 3 , MYBL 2 , ZNF 217 , and TNFRSF6B ( 39 % each ) ; and MSH 2 , TERC , SERPINE 1 , AFM137XA11 , IGF1R , and PTPN 1 ( 33 % each ) . ^^^ |
|
| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P18031 and P08069 |
Pubmed |
SVM Score :0.0 |
| NA |
|