Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: Q9UN19 and P07948	Pubmed	SVM Score :0.0
Src , Lyn and Lck tyrosine kinases phosphorylate DAPP 1 at Tyr ( 139 ) in vitro at similar rates in the presence or absence of PtdIns ( 3 , 4 , 5 ) P ( 3 ) , and overexpression of these kinases in HEK 293 cells induces the phosphorylation of Tyr ( 139 ) . ^^^
Interacting proteins: Q9UN19 and P07948	Pubmed	SVM Score :0.0
We show that in DT 40 chicken B cell lines , antibody stimulation leads to PI3K dependent tyrosine phosphorylation of DAPP 1 that is lost in Lyn or Syk deficient cell lines but not Btk deficient cell lines . ^^^ Finally , in vitro we find lipid modified Src to be the most effective DAPP 1 tyrosine kinase ( versus Syk , Lyn , Btk , and Bmx ) ; phosphorylation of DAPP 1 but not Src autophosphorylation is stimulated approximately 10 fold by PtdIns ( 3 , 4 , 5 ) P ( 3 ) ( IC ( 50 ) = 150 nm ) and phosphatidylinositol 3 , 4 bisphosphate but not by their nonbiological diastereoisomers and depends on PH domain mediated binding of DAPP 1 to PtdIns ( 3 , 4 , 5 ) P ( 3 ) containing membranes . ^^^