Interacting proteins: P16671 and P07948 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: P16671 and P07948 |
Pubmed |
SVM Score :0.0 |
CD 36 , active Lyn , along with inactive Src and PLCgamma 2 co localize in small raft complexes in resting platelets . ^^^ |
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Interacting proteins: P16671 and P07948 |
Pubmed |
SVM Score :0.0 |
In addition , glycoprotein 4 ( GPIV , CD 36 ) , one of the major platelet membrane glycoproteins , was associated in a complex with the Fyn , Yes , and Lyn proteins in platelet lysates . ^^^ Membrane glycoprotein 4 ( CD 36 ) is physically associated with the Fyn , Lyn , and Yes protein tyrosine kinases in human platelets . ^^^ |
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Interacting proteins: P16671 and P07948 |
Pubmed |
SVM Score :0.0 |
Biochemical characterization of the Triton 10 100 insoluble fraction showed it to be cholesterol rich , greatly and specifically enriched in the plasma membrane glycoprotein CD 36 , and also to contain Src and the Src related kinase , Lyn . ^^^ |
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Interacting proteins: P16671 and P07948 |
Pubmed |
SVM Score :0.0 |
Translocation of the Csk homologous kinase ( Chk / Hyl ) controls activity of CD 36 anchored Lyn tyrosine kinase in thrombin stimulated platelets . ^^^ Chk and Lyn , but not Csk and c Src , co fractionated in the higher density lysate fractions of resting platelets , with Chk being found to localize close to CD 36 ( membrane glycoprotein 4 ) anchored Lyn . ^^^ These results suggest that Chk , but not Csk , may function as a translocation controlled negative regulator of CD 36 anchored Lyn in thrombin induced platelet activation . . ^^^ |
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Interacting proteins: P16671 and P07948 |
Pubmed |
SVM Score :0.0 |
This fraction is also greatly enriched in the transmembrane glycoprotein CD 36 , known to associate with Lyn PTK , but in transfection studies we could find no evidence to suggest that CD 36 affects the distribution or function of Lyn . ^^^ |
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Interacting proteins: P16671 and P07948 |
Pubmed |
SVM Score :0.0 |
In this study , we demonstrate that in microglia and other tissue macrophages , beta amyloid initiates a CD 36 dependent signaling cascade involving the Src kinase family members , Lyn and Fyn , and the mitogen activated protein kinase , p44 / 42 . ^^^ |
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Interacting proteins: P16671 and P07948 |
Pubmed |
SVM Score :0.0 |
Using macrophages derived from wild type and Cd 36 ( / ) mice to distinguish CD 36 specific events , we show that fibrillar apolipoprotein C 2 activates a signaling cascade downstream of this receptor that includes Lyn and p44 / 42 MAPKs . ^^^ |
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Interacting proteins: P16671 and P07948 |
Pubmed |
SVM Score :0.0 |
Microglial activation might involve beta amyloid binding and activation of cell surface immune and adhesion molecules such as CD 45 , CD 40 , CD 36 and integrins , with the subsequent recruitment of Src family tyrosine kinases such as Fyn , Lyn and Syk kinases . ^^^ |
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