We identified 30 tyrosine kinases expressed in these tissues : they include 10 non receptor tyrosine kinases ( yes , fyn , lyn , brk , abl , arg , jak 1 , jak 3 , tyk 2 and itk ) , 17 receptor tyrosine kinases ( erbB 2 , PDGF Ralpha , PDGF Rbeta , kit , c fms , met , ron , FGF R 1 , FGF R 2 , FGF R 3 , FGF R 4 , cek 5 , tie 1 , tkt , axl , sky and Ins R ) , 2 dual kinases ( mek and sek ) and one possible novel kinase . ^^^ |
Six known PTKs ( YES , FGR , LYN , HCK , PDGFB R , and CSF 1 R ) , as well as two additional members of this enzyme family , were detected in lung . ^^^ |