| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| Cyclic AMP acutely stimulates translocation of the major insulin regulatable glucose transporter GLUT 4 . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| A short term exposure ( 4 h ) of cells to cholera toxin or dibutyryl cyclic AMP resulted in a 3 to 4 fold increase in deoxyglucose transport which was associated with significant redistribution of both the HepG2 / erythrocyte ( GLUT 1 ) and muscle / adipocyte ( GLUT 4 ) glucose transporters from low density microsomes to the plasma membrane fraction . ^^^ In contrast , cells exposed to cholera toxin or dibutyryl cyclic AMP for 12 h exhibited elevations in total cellular contents of GLUT 1 ( but not GLUT 4 ) protein to about 1 . 5 and 2 . 5 fold above controls , respectively . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| Cyclic AMP induced transcriptional repression of the insulin responsive glucose transporter ( GLUT 4 ) gene : identification of a promoter region required for down regulation of transcription . ^^^ The mechanism ( s ) by which cyclic AMP represses transcription of the GLUT 4 gene was investigated . 3T3 L 1 preadipocytes were stably transfected with a series of 5 ' deletion mutants of the mouse GLUT 4 gene promoter fused to the bacterial CAT gene and then were induced to differentiate into adipocytes . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| Preincubation of adipocytes with calcium channel blocker ( nitrendipine ) and cyclic AMP antagonist ( RpcAMP ) restored GLUT 4 intrinsic activity in the PTH treated cells . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| Chronic activation of 5 ' AMP activated protein kinase increases GLUT 4 , hexokinase , and glycogen in muscle . ^^^ This study was designed to determine whether chronic chemical activation of AMP activated protein kinase ( AMPK ) would increase glucose transporter GLUT 4 and hexokinase in muscles similarly to periodic elevation of AMPK that accompanies endurance exercise training . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| Exercise acutely stimulates muscle glucose transport and also brings about an adaptive increase in the capacity of muscle for glucose uptake by inducing increases in GLUT 4 and hexokinase . ( 1 ) Recent studies have provided evidence that activation of AMP protein kinase ( AMPK ) is involved in the stimulation of glucose transport by exercise . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| GLUT 4 , AMP kinase , but not the insulin receptor , are required for hepatoportal glucose sensor stimulated muscle glucose utilization . ^^^ Here , we sought to further determine the portal sensor signaling pathway by selectively evaluating its dependence on muscle GLUT 4 , insulin receptor , and the evolutionarily conserved sensor of metabolic stress , AMP activated protein kinase ( AMPK ) . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| These beneficial effects on glucose metabolism were associated with increased AMP kinase and hexokinase activities , as well as elevated levels of GLUT 4 and myocyte enhancer factor 2 proteins A and D in skeletal muscle . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| It is concluded that beyond AMP activated protein kinase the contraction induced and AMPK mediated signal branches off into separate mobilization of GLUT 4 and of FAT / CD36 , and that dipyridamole activates a yet unidentified target in the FAT / CD36 mobilizing branch . . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| AMP kinase is not required for the GLUT 4 response to exercise and denervation in skeletal muscle . ^^^ AMP activated protein kinase ( AMPK ) activity in skeletal muscle is also increased by exercise , and GLUT 4 mRNA is increased in mouse skeletal muscle after treatment with AMPK activator 5 aminoimidazole 4 carboxamide 1 beta D ribofuranoside ( AICAR ) . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| AMP kinase , GLUT 4 and myosin heavy chain IIx are proposed as candidates for physical inactivity modulated genes that have an altered function that may trigger a crossing of a threshold to disease . ^^^ |
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| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT 4 levels in muscle . ^^^ |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P14672 |
Pubmed |
SVM Score :0.0 |
| NA |
|