| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| Mitochondrial and tissue AdNs ( ATP , ADP , and AMP ) were determined in the LAD supplied and left circumflex supplied ( control ) regions of the heart . ^^^ |
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| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| The myocardial blood flow supplied by the LAD increased from 56 + / 3 to 237 + / 23 ml . min 1 per 100 g myocardium and the rate of cyclic AMP release in the venous blood near the origin of the GCV increased from 15 . 2 + / 3 . 0 to 104 . 8 + / 29 . 5 pmol . min 1 per 100 g myocardium . ^^^ The adenosine induced release of cyclic AMP did not result from an action of the substance on the platelets in the coronary circulation since adenosine concentration comparable to that achieved in the LAD did not modify the cyclic AMP plasma level of arterial blood in vitro . ^^^ |
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| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| AMP was higher in the LAD compared to the CFX segment . ^^^ |
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| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| Each vascular territory ( left anterior descending artery [ LAD ] left circumflex artery and posterior descending artery [ PDA ] ) was graded as either having ( AMP = 1 ) or not having ( AMP = 0 ) blood flow through an unobstructed major vessel in the territory . ^^^ With regard to overall mortality ( Kaplan Meier curves ) , univariate analysis also revealed correlations with overall AMP ( p < 0 . 001 ) , LAD AMP ( p = 0 . 005 ) , previous CABG ( p = 0 . 003 ) and PDA AMP ( p = 0 . 05 ) each individually correlated with mortality . ^^^ |
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| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| Endothelium dependent relaxation produced by h ( alpha ) CGRP was accompanied by increases in cyclic AMP and cyclic GMP , that were not inhibited by h ( alpha ) CGRP ( 8 37 ) ( 10 ( 5 ) M ) . 4 In porcine LAD and AIA , h ( alpha ) CGRP produced relaxation in an endothelium independent manner . ^^^ In LAD artery , h ( alpha ) CGRP induced relaxation was accompanied by increases in cyclic AMP that were inhibited by h ( alpha ) CGRP ( 8 37 ) ( 10 ( 7 ) 10 ( 5 ) ) . 5 In conclusion , the antagonist affinity for h ( alpha ) CGRP ( 8 37 ) in porcine coronary artery is consistent with a CGRP 1 receptor , while the lack of h ( alpha ) CGRP ( 8 37 ) antagonism in rat aorta could suggest either a CGRP receptor different from CGRP 1 and CGRP 2 type , or a non CGRP receptor . . ^^^ |
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| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| In univariate analysis , P max , P dispersion , P amp max , P amp dispersion , LAD , LVEF , and old age were significant predictors of chronic AF ( p < 0 . 001 , p < 0 . 01 , p < 0 . 01 , p < 0 . 01 , p = 0 . 003 , p = 0 . 02 , and p = 0 . 01 , respectively ) . ^^^ |
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| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| From the mini review of research works published during the last 25 years , the following basic view is clear : a ) animal KGDHC is very sensitive to ADP , P ( 1 ) , and Ca2+ ; b ) these positive effectors increase manifold the affinity of KGDHC to alpha ketoglutarate ; c ) KGDHC is inhibited by ATP , NADH , and succinyl CoA ; d ) the ATP effect is realized in several ways , probably mainly via opposition versus ADP activation ; e ) NADH , besides inhibiting dihydrolipoamide dehydrogenase component competitively versus NAD+ , decreases the affinity of alpha ketoglutarate dehydrogenase to substrate and inactivates it ; f ) thioredoxin protects KGDHC from self inactivation during catalysis ; g ) bacterial and plant KGDHC is activated by AMP instead of ADP . ^^^ |
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| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P07741 and P09622 |
Pubmed |
SVM Score :0.0 |
| NA |
|