| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.58275145 |
| To study this reduced DNA binding , we examined the ability of the nuclear translocated transcription factors activator protein 1 ( AP 1 ) , nuclear factor kappa B ( NF kappa B ) and cyclic AMP response element binding protein ( CREB ) to bind to their DNA binding sites and to interact with GR in PBMC from patients with steroid sensitive and steroid resistant asthma . 0.58275145^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| Computer analysis also revealed five putative cyclic AMP response elements ( CREs ) in the GR promoter . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| Malate oxidoreductase decarboxylating ( MOD ) and mannose phosphate isomerase ( MPI ) segregated concordantly , confirming an established linkage relationship ; adenine phosphoribosyltransferase ( APRT ) segregated concordantly with glutathione reductase ( GR ) which is known to be on chromosome 8 ; alpha galactosidase was observed to be syntenic with hypoxanthine phosphoribosyltransferase ( HPRT ) , and 10 linked enzyme . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| WEHI7 . 2 murine lymphocytes undergo apoptotic death when exposed to glucocorticoids or elevated levels of intracellular cyclic AMP ( cAMP ) , and these pathways are initiated by the glucocorticoid receptor ( GR ) and protein kinase A , respectively . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| The 5 HT induced enhancement of cyclic AMP accumulation in amitriptyline treated cells was attenuated by the 5 HT 4 receptor antagonists , GR 113808 and ICS 205 930 , with relatively low potency . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| We show that a full response to glucocorticoids requires two DNA segments : 1 ) a glucocorticoid response unit ( GRU ) , centered at about position 400 , which contains two accessory factor elements ( AF 1 and AF 2 ) and two glucocorticoid receptor binding sites ( GR 1 and GR 2 ) , and 2 ) a basal promoter / cyclic AMP response element ( E / CRE ) at about position 90 , which binds the transcription factor CREB . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| RP 67580 , CP 96345 and GR 94800 , a NK 2 antagonist , were either competitive or uncompetitive inhibitors of inositol phosphates or cyclic AMP formations induced by [ Pro 9 ] SP , septide or NKA , independently of the agonist or the response studied . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| GR 113808 inhibited the cyclic AMP formation induced by 5 HT with a log Ki value of 9 . 1 and an apparent pA 2 value of 9 . 2 . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| The 5 HT 4 receptor antagonist , GR 113808 , inhibited cyclic AMP formation and relaxation induced by 5 HT with log Ki values of 9 . 1 ( cyclic AMP ) and 8 . 9 ( relaxation ) and apparent pA 2 values of 9 . 2 ( cyclic AMP ) and 9 . 5 ( relaxation ) . 4 . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| Accumulation of cyclic AMP stimulated by 5 HT ( 10 microM ) was inhibited by methiothepin ( IC 50 = 21 + / 13 nM ) but not by pindolol , SCH 23390 , ICS 205 930 or GR 113808 . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| However , the selective A 1 receptor agonist GR 79236 ( 3 microg / kg + 0 . 3 microg / kg / min i . v . ) did not reduce infarct size , which suggests that under these experimental conditions , stimulation of adenosine A 2 receptors is important for the cardioprotective effect of AMP 579 . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| The ability of the 5 HT ( 1B ) receptor antagonist GR 127935 ( 5 mg / kg s . c . ) to increase 5 HT levels in both hippocampus and hypothalamus was unaffected by chronic ECS . 8 OH DPAT ( 0 . 2 mg / kg s . c . ) increased cyclic AMP levels in hippocampus measured by in vivo microdialysis approximately 2 fold . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| The cyclic AMP response element binding protein ( CREB ) and the glucocorticoid receptor ( GR ) are altered by chronic treatment with antidepressants . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| We provide evidence that chronic activation of the glucocorticoid receptor ( GR ) in clonal neurons inhibits the transcriptional activity of the cyclic AMP response element binding protein ( CREB ) , which is believed to be involved in memory processes . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| Studies are testing a hypothesis that hippocampal transcriptional mechanisms and gene expression profiles linked to activator protein 1 ( AP 1 ) and glucocorticoid receptor ( GR ) , mineralocorticoid receptor ( MR ) or cyclic AMP response element binding protein ( CREB ) families of transcription factors distinguish successful or unsuccessful aging and cognition . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| Mechanistically , morphine exposure induced a cyclic AMP and protein kinase A dependent upregulation of neuronal glucocorticoid receptors ( GR ) within the spinal cord dorsal horn , which was maintained after discontinuation of morphine administration and significantly enhanced upon a second cycle of morphine exposure . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| Activation of the genes encoding gluconeogenic enzymes is mediated by hormone responsive transcription factors such as the cyclic AMP response element binding protein ( CREB ) and the glucocorticoid receptor ( GR ) . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| Substances that increase the intracellular cyclic AMP concentration also strengthen the transactivity of the GR and coincubation with caffeine further reinforces this potentiation , indicating that caffeine mediated enhancement of GR transcriptional function is due to the inhibitory activity of caffeine on the cyclic AMP phosphodiesterase . ^^^ |
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| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| Several transcription factors have been implicated in the inflammatory process in asthma , including the glucocorticoid receptor ( GR ) , NFkappaB , Activator Protein 1 ( AP 1 ) , Nuclear Factor of Activated T cells ( NF AT ) , cyclic AMP Response Element Binding Protein and more recently , the CCAAT / Enhancer Binding Protein ( C / EBP ) , Peroxisome Proliferator activated Receptor ( PPAR ) and the bZIP transcription factor , Nrf 2 . ^^^ |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P00390 and P07741 |
Pubmed |
SVM Score :0.0 |
| NA |
|