| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.8899021 |
| To a lesser extent , the cytoplasmic domain of CD 2 was also shown to interact with CD 45 , as demonstrated by an increase in co immunoprecipitated phosphatase activity observed following replacement of the CD 58 cytoplasmic domain with that of CD 2 . 0.8899021^^^ To investigate the structural requirements for an association of CD 2 with the tyrosine phosphatase CD 45 and the zeta chain of the T cell receptor ( TCR ) / CD3 / zeta complex , we have expressed in mouse EL 4 T cells a series of human CD 2 chimeric and mutant proteins . 0.55545369^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Stimulation of IFN gamma , TNF alpha , and TNF beta secretion in IL 2 activated T cells : costimulatory roles for LFA 1 , LFA 2 , CD 44 , and CD 45 molecules . ^^^ These molecules are the lymphocyte function associated antigen 1 ( LFA 1 ) , lymphocyte function associated antigen 2 ( LFA 2 ) , CD 44 , and CD 45 . ^^^ LFA 1 is an integrin , LFA 2 is a member of the immunoglobulin supergene family , CD 44 is homologous to the cartilage link proteins , and CD 45 is a tyrosine phosphatase . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Cell surface molecules other than CD 4 , including TCR , CD 3 , CD11a , CD 2 , CD 45 , CD 44 , and MHC class 1 , remained identical on D10H and D10L sublines as on D 10 wild type cells . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Further evidence of a linkage between CD 2 and CD 45 isoforms was obtained . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| CD 2 can mediate TcR CD 3 independent and CD 45 dependent activation of p56lck . ^^^ By isolating CD 45 mutants from Jurkat cells , we observed that surface expression of the tyrosine phosphatase CD 45 is required in order to increase p56lck activity following CD 2 stimulation , while CD 4 induced activation of the kinase remained unchanged . ^^^ These data provide evidence for a specific functional linkage between CD 2 and p56lck , in which CD 45 may play an essential role . . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Cross linking of CD 2 with CD 3 receptors augmented the phosphorylation of PLC gamma 1 on tyrosine , whereas ligation of the CD 45 tyrosine phosphatase with CD 2 receptors prevented PLC gamma 1 tyrosine phosphorylation . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Both normal and WAS T cell lines express cell surface molecules CD 2 , CD 3 , T cell receptor alpha / beta , human histocompatibility leukocyte antigen class 1 , CD 45 and CD11a , and varying ratios of CD 4 and CD 8 , and are negative for natural killer cell and monocyte surface molecules . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Biotinylation and radioiodination have been compared for labeling lymphocyte surface proteins and the labeled proteins symmetrically immunoprecipitated with antibodies recognizing major lymphocyte markers such as the murine Thy 1 , CD 25 ( the alpha subunit of the interleukin 2 receptor ) , CD 45 , and human CD 2 glycoproteins . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| MRL lpr / lpr ( lpr ) mice develop a polyclonal accumulation of abnormal peripheral T lymphocytes , which bear surface alpha beta TCR , CD 3 , and the B 220 isoform of CD 45 , but lack CD 4 , CD 8 , and CD 2 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| An isoform specific association pattern was observed : CD 2 co capped with CD 45 molecules recognized by UCHL 1 mAb ( CD45R0 ) . ^^^ In conclusion , this work shows that in human T cells different CD 45 isoforms are associated to different surface molecules : LFA 1 is associated to CD45RA , CD 2 to CD45R0 and CD 4 and CD 8 presumably to CD45RC . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Tyrosine phosphatase CD 45 is required for T cell antigen receptor and CD 2 mediated activation of a protein tyrosine kinase and interleukin 2 production . ^^^ Additionally , stimulation of T lymphocytes by way of the accessory molecule CD 2 requires the expression of CD 45 . ^^^ The mutation in the CD 45 deficient cell specifically impairs signal transduction by the T cell receptor and CD 2 because activation events by way of another accessory molecule , CD 28 , are unimpaired . . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Activation of MAP 2 kinase activity by the CD 2 receptor in Jurkat T cells can be reversed by CD 45 phosphatase . ^^^ We also demonstrate that the common CD 45 isoform , when cross linked to CD 2 by mAb , could inhibit the MAP 2K response during both induction as well as the disappearing phase of the response . . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Anti CD 2 receptor antibodies shared with anti CD 3 antibodies the ability to potentiate dose dependently the adenosine and forskolin stimulated cyclic adenosine monophosphate ( cAMP ) accumulation , whereas stimulation of the CD 45 receptor had no effect on cyclase activity . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Here we examine the role of CD 4 , CD 8 , CD 2 , and CD 45 in the regulation of intracellular Ca2+ levels in mature and immature thymocytes . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| In addition , mAb to the adhesion molecules LFA 3 , CD 2 , LFA 1 , CD 29 , and to the tyrosine phosphatase CD 45 also inhibited proliferation , indicating the involvement of T to T cell interactions . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The beads were coated with monoclonal antibodies directed against the leukocyte / lymphocyte antigens CD 2 , CD 19 or CD 45 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Association of CD 2 and CD 45 on human T lymphocytes . ^^^ This view is supported by the finding that most monoclonal antibodies directed at the CD 45 molecules are strongly co mitogenic with CD 2 but not CD 3 monoclonal antibodies . ^^^ As the intracytoplasmic domains of CD 45 have tyrosine phosphatase activity these functional effects could be explained by a physical association between CD 2 and CD 45 . ^^^ Using chemical crosslinking techniques , we now show that CD 45 is linked to CD 2 on the surface of human T lymphocytes . . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Co aggregation of CD 2 and CD 45 , a tyrosine phosphatase , results in inhibition of intracellular calcium elevation and T cell proliferation . ^^^ Similar results are observed when CD 2 and CD 45 are independently cross linked rather than co aggregated . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Association of CD 2 and T 200 ( CD 45 ) in mouse T lymphocytes . ^^^ A monoclonal antibody ( mAb 12 15 ) reactive with the mouse CD 2 was found to co precipitate a high molecular weight glycoprotein from mouse thymocyte , splenic lymphocyte , Con A blast , and T cell tumor detergent lysates which was identified as the leukocyte common T 200 glycoprotein ( CD 45 ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| In addition , they expressed CD 45 antigen and T cell antigens ( CD 2 , CD 4 ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| A majority of the cells from peripheral blood coexpressed the antigens against MAbs CD 2 , CD 3 , CD 4 , CD 5 , Ti ( WT 31 ) , CD 25 , CD 38 , CD 45 , and CD 29 , but did not express the antigens against CD 1 , CD 13 , CD 14 , CD 33 , CD 36 , CD 10 , CD 19 , CD 20 , CD 21 , CD 24 , CD 41 , CD 42 , CD45RA , CD 56 , and CD 57 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Immunoperoxidase showed tumor cells to be strongly reactive for Leu M 1 ( CD 15 ) , BER H 2 ( CD 30 ) , Leu 3 ( CD 4 ) , and T 11 ( CD 2 ) and weakly reactive for Leu 4 ( CD 3 ) but nonreactive for EMA , LCA , lysozyme , Leu 9 , Leu M 3 , Leu M 5 , and immunoglobulin light chains . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The neoplastic cells expressed CD 2 , NKH 1 , HLA DR and leukocyte common antigen , but lacked other T cell , B cell and myeloid markers . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Such macrophages also expressed CD 4 ( Leu 3a and 3b ) and 2H4 , which are the cell membrane determinants of suppressor inducer T lymphocyte ; CD 2 ( Leu 5b ) , which is a marker of pan T cell ; Leu M 3 , Leu M 5 and Mac 1 , which are the markers of monocyte and macrophage lineage ; leukocyte common antigen , which is a marker of bone marrow derived cell ; and alpha antichymotrypsin , which is a glycoprotein associated with macrophages . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| In this article , Barton Haynes and colleagues discuss the sequential expression of CD 7 , CD 4 , CD 8 , CD 3 , CD 2 , CD 1 , CD 45 , TCR gamma delta and TCR alpha beta , and propose a model defining the stages of T cell precursors during fetal ontogeny . . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Subsets of thymopoietic rat thymocytes defined by expression of the CD 2 antigen and the MRC OX 22 determinant of the leukocyte common antigen CD 45 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Crosslinking of CD 2 , CD 4 and CD 45 with Ti / CD3 to several of these antigens can augment the minimal signal induced by antigen binding to the Ti / CD3 complex . ^^^ Crosslinking of CD 4 with the Ti / CD3 complex preferentially activated the CD4+ CD45+ RA subset , while soluble antibodies to CD 2 preferentially affected the CD 45 CD45RA+ subset . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| These immature cells are TdT and do not express membrane CD 3 ( mCD 3 ) or TCR beta identified by beta F 1 , but show CD 7 and CD 45 positivity without CD 1 , CD 2 , CD 5 , CD 4 , CD 8 , CD 10 , and class 2 Ag . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Single parameter immunophenotyping results determined that the granulated as well as the agranulated blast cells were NK lymphocytes ( CD 45 , NKH 1 , CD 2 , LEU 17 , and CD 16 positive ; CD 3 , CD 8 , and LEU 7 negative ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Similarly , proliferation after stimulation of the CD 2 and CD 28 receptors was inhibited when a CD 45 mAb was crosslinked to either CD 2 or CD 28 mAbs , but not when a CD 45 specific mAb was bound to the cell surface separately . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| CD2 . 1 mAb by itself is unable to induce ( Ca2+ ) 1 mobilization ; in addition , preincubation with CD2 . 1 mAb did not modify the CD 2 , CD 3 , CD 45 , or CD 28 immunoprecipitation patterns . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Abnormalities which could contribute to this defect include low expression and rapid TCR / CD3 modulation , loss of CD 4 , CD 8 , CD 2 and Ly 6 . 2 , aberrant expression of CD 45 , and constitutive elevations of inositol phospholipid turnover , tyrosine phosphorylation , and expression of the p59fyn protein tyrosine kinase ( PTK ) and a few other protooncogenes . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| We previously reported that secretion of cytokines by IL 2 activated T cells ( LAK T cells ) is dependent on the initial cross linking of the T cell receptor ( TCR ) CD 3 molecular complex , but the cross linking of accessory molecules , such as LFA 1 , CD 2 , CD 44 and CD 45 , on LAK T cells can enhance this cytokine production . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| CD 2 , LFA 1 and CD 45 molecules were normal in charge and molecular weight . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The expression of other adhesion molecules , LFA 1 alpha ( CD11a ) , LFA 1 beta ( CD 18 ) , Pgp 1 ( CD 44 ) , CD 45 , MEL 14 ( L selectin ) , and VLA 4 alpha ( CD49d ) , were all increased as a result of anti CD 2 treatment , whereas CD 25 ( IL 2R ) , CD 48 ( CD 2 ligand ) , and ICAM 1 ( CD 54 ) remained unchanged . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Surface expression of isoforms of CD 45 , a component of the T cell receptor complex , as well as of the accessory molecule , CD 2 , were assessed by flow cytometry of splenic mononuclear cell suspensions . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Mice homozygous for lpr and gld develop lymphadenopathy characterized by the progressive accumulation of an unusual population of CD 4 , CD 8 , CD 2 , IL 2R double negative ( DN ) T cells that express reduced levels of TCR alpha / beta , high levels of CD 45 ( B 220 ) and Ly 6C and variable levels of CD 69 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| ALL leukemia T cells ( which express very low levels of CD 45 ) , both CD 3 and CD 2 stimulation induced only very weak protein tyrosyl phosphorylation . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Flow cytometry analysis revealed that these cells express CD 45 , CD 56 , CD 2 , CD 7 , CD11a , CD 18 , CD 69 and the intermediate affinity ( p 70 ) IL 2 receptor ( IL 2R ) but not CD 57 , CD 16 , CD 3 , CD 4 , CD 5 , CD 8 , CD45RA , CD 25 , or the high affinity p 55 IL 2R . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The T CLL cells coexpressed antigens detected by MAbs CD 2 , CD 3 , CD 4 , CD 5 , Ti ( TcR alpha / beta ; WT 31 ) CD 45 and CD45RA , but did not express any other antigens including CD 1 , CD 8 , CD 29 , and TCR gamma / delta , Ti gamma A and TQ 1 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Activities found in four lots each of horse ATG ( ATGAM , Upjohn ) , rabbit and horse ATG ( thymoglobulin and lymphoglobulin , Merieux ) , horse ALG ( Minnesota ) , and rabbit ATG ( Fresenius ) have been compared for CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , CD11a , CD 18 , CD 28 , CD 44 , CD 45 , and TCR alpha / beta antigens . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| While one RO type CD7+ CD 5 CD 2 and one RO type CD7+ CD 5 CD2+ cases were not in accord with this sequence , the pattern of CD 45 RA / RO antigen expression in most of T lineage neoplasms could be determined by the respective stage of differentiation . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| In human T cells CD 45 is reported to associate with both cell surface and intracellular molecules including CD 2 , CD4 / CD8 , CD 5 , p56lck and p59fyn . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Our results demonstrate that whereas expression of major histocompatibility complex ( MHC ) molecules , CD 45 , Mac 1 , LFA 1 , B cell markers , macrophage markers and some T cell markers ( as CD 2 , CD 4 and CD 8 ) did not undergo changes in culture , the level of expression of the adhesion molecules VLA 4 and ICAM 1 , and the T cell markers CD 5 , CD 25 and Thy 1 increased after 14 h incubation at 37 degrees C . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Peripheral lymphoid tissues of lpr mice contain a large proportion of TCR alpha beta / CD3+CD4 CD 8 T cells that lack surface CD 2 and express the B cell isoform of CD 45 , B 220 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Previous studies have reported an association of the cell surface adhesion molecule CD 2 with the T cell receptor and with CD 45 on mouse and human T lymphocytes . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| In addition , by using a mitogenic combination of CD 2 plus CD 45 MoAb , median proliferation of T cells was severely depressed in patients : 10 . 577 ct / min versus 34 . 685 ct / min in controls ( P = 0 . 005 ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Similarly , activation and internalization of p56lck were observed using a combination of anti CD 45 ( MC5 / 2 ) and anti CD 2 ( T 11 ( 2 ) ) mAb , suggesting that a functional complex consisting of CD 45 , CD 2 and p56lck was formed upon cell triggering . ^^^ Taken together , these results suggests that : ( 1 ) CD 45 participates in the regulation of p56lck kinase activity in vivo and that ( 2 ) CD 45 could play a mediator role in the stimulation and endocytosis of p56lck through the CD 2 pathway . . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| In addition to their induction by IL 1 alpha , the IL 5 , IL 6 , and IL 10 genes were also induced by mAbs to CD 2 and to CD 45 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Restoration of CD 2 mediated signaling by a chimeric membrane protein including the cytoplasmic sequence of CD 45 . ^^^ We showed previously that the TCR and CD 2 fail to couple efficiently with their signal transduction machinery in J45 . 01 , a CD 45 deficient variant of the Jurkat T cell line . ^^^ These findings demonstrate that the cytoplasmic domain of CD 45 , expressed as a chimeric membrane protein , is sufficient for mediating signal transduction through CD 2 as well as through the TCR complex . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The binding frequencies ( % positive ) for anti CD 2 , CD 3 , CD 5 , CD 6 , CD 7 , CD 8 , CD11a , CD 14 , CD 18 , CD 19 , CD 45 , T cell receptor , and HLA DR were not significantly affected . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Upon activation through the CD 2 or the CD 45 receptors the kinase activity of p56lck is temporarily increased . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Immunophenotypically , the neoplastic cells expressed CD 2 , CD 3 , CD 7 , CD 16 , CD 45 , CD 56 , and the gamma / delta T cell receptor on the surface membrane . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Percentages of the different lymphocytes subsets , including CD 2 ( T cells ) ; CD 4 ; CD 45 RA ( suppressor inducer / virgin T cells ) ; CD 4 CD29 ; CD 8 ; CD 19 ( B cells ) as well as interleukin 2 ( IL 2 ) receptor ( CD 25 ) and class 2 antigen ( HLA DR ) expression , were analyzed by flow cytometry . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The CD 45 negative cells expressed CD 2 , CD 53 , and NKR P 1 , but mAb induced perturbations of these molecules did not induce protein tyrosine phosphorylations and increases in the concentration of cytoplasmic free calcium , as occurred in the wild type RNK 16 . ^^^ These studies suggest that CD 45 is required for the response of RNK 16 cells to target cells and for signaling through CD 2 , CD 53 , and NKR P1 . . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| None of the other cytokines tested ( IL 1 alpha , IL 6 , TNF alpha , IFN alpha , IFN gamma ) supported growth of NK 92 cells which have the following characteristics : surface marker positive for CD 2 , CD 7 , CD11a , CD 28 , CD 45 , CD 54 , CD56bright ; surface marker negative for CD 1 , CD 3 , CD 4 , CD 5 , CD 8 , CD 10 , CD 14 , CD 16 , CD 19 , CD 20 , CD 23 , CD 34 , HLA DR . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| At the permissive temperature , MegT cells exhibit the characteristics of early 2N and 4N megakaryocytes which include the presence of specific gene products such as PF 4 , glycoprotein IIb , acetylcholinesterase , and CD 45 as well as the absence of molecular markers of other cell lineages such as the macrophage marker Mac 1 , the T helper cell marker CD 4 , the mast cell marker IgE , the T cell marker CD 2 or the erythroid cell marker alpha globin . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Only 3 of 31 tested CD antigens ( CD 2 , LAK 1 and CD 45 ) were passed through this first strongly restricted experimental screening . ^^^ The EDTA released LAK 1 antigen , but not CD 2 and CD 45 , interact with TNF alpha and cell surface via a mannose inhibitable interaction dependent on the presence of Ca2+ ions . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Subpopulations of synovial and inflammatory cells were identified with MoAbs against cell surface glycoproteins present on B lymphocytes ( CD 45 ) , T lymphocytes ( CD 2 , CD 4 , CD 8 ) , macrophages ( CD 14 ) and endothelial cells . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Immunophenotypically , the cells displayed markers of true natural killer cells ( positive CD 2 , CD 56 , CD 45 , CD 7 , CD 16 , and CD 33 ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The positive and negative effects of CD 45 are sensitive to the composition of CD 45 in receptor complexes , and may be regulated by specific associations of CD 45 isoforms with other receptors such as CD 3 TCR , CD 2 and CD4 . . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Several groups have reported a physical interaction between distinct isoforms of CD 45 and CD 2 , CD 4 , and the TCR CD 3 complex . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| We have studied the expression of several leukocyte surface markers ( CD 2 , CD 3 , CD 4 , CD 8 , CD 7 , CD 26 , CD 25 , CD 14 , CD 18 , kCD 20 , CD 43 , CD 45 , CD45R , CD 71 and HLA class 1 and 2 ) and we find no differences in their expression between PPL . 1 and its parental Jurkat cell line . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Analysis of expression of other adhesion molecules demonstrated that CD11a , CD 18 , CD 44 , CD 45 , CD 48 , CD 54 , and CD62L were significantly increased by either anti CD 2 or anti CD 3 mAbs while the combination was not synergistic . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Expression of other integrin , selectin , or immunoglobulin superfamily molecules ( CD11a , CD 18 , CD 44 , CD 45 , CD 48 , CD 54 and CD62L ) were all significantly increased by anti CD 2 or anti CD 3 mAbs . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| A number of T cell surface transmembrane molecules such as CD 2 , CD 4 , CD 8 , lymphocyte functional antigen ( LFA ) 1 and CD 45 are known to interact functionally with the T cell receptor ( TCR ) complex during T cell activation . ^^^ Two types of large complexes containing protein tyrosine kinases were observed : the first one contained CD 3 and the transmembrane proteins CD 2 , CD 4 , CD 5 , CD 6 , CD 7 , CD 8 , CD11a , CD 38 , CD 43 , CD 45 , CD 71 , CD 98 and CD 99 and the other contained mainly the GPI anchored proteins CD 48 , CD 55 , CD 59 and CDw 108 as well as a fraction of CD 4 and CD 8 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Percentages of the different lymphocytes subsets , including CD 2 ( T cells ) , CD 4 , CD 45 RA ( suppressor inducer / virgin T cells ) , CD 4 , CD 29 , CD 8 , CD 19 ( B cells ) , as well as interleukin 2 ( IL 2 ) receptor ( CD 25 ) and class 2 antigen ( human leukocyte antigen HLA DR ) expression , were analyzed by flow cytometry . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| We have used this method to generate functional sFv to human CD 2 , CD 3 , CD 4 , CD 8 , CD 28 , CD 40 , CD 45 and to murine CD 3 and gp 39 , from hybridomas producing murine , rat , or hamster antibodies . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Membrane antigens SLA DR and CD 45 were found by day 22 , membrane molecules MG 7 , 8 / 1 , CD 1 , CD 2 and 74 22 by day 28 , Gamma / delta T cells were found initially in extrathymic sites ( in the liver ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Assays for the specific surface antigens CD 45 , CD 2 , CD 4 , CD 8 , CD 1 , MHC class 2 , and N 1 were employed to develop immunophenotypic profiles within the gated lymphocyte clusters from each TIL and PBL suspension . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| These effects do not correlate with changes in the expression of cell surface molecules implicated in antigen recognition , like TCR / CD3 , CD 2 , LFA 1 , or CD 45 , or with lower p56lck or p59fyn activity in the mutant cells . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| While cross linking of several adhesion molecules ( CD 2 , CD 44 , alpha 4 integrin , LFA 1 ) by antibody did not result in a significant reduction of the expression of L selectin , antibodies against CD 45 and Thy 1 . 2 , both involved in the regulation of lymphocyte activation , induced loss of cell surface L selectin within minutes , even at 4 degrees C , by shedding into the supernatant . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Whole blood samples were labelled with the nuclear dye LDS 751 and with antibodies to HLA DR or belonging to CD 2 , CD 3 , CD 4 , CD 7 , CD 8 , CD 10 , CD 13 , CD 14 , CD 19 , CD 20 , CD 29 , CD 33 , CD 45 , CD45RA , CD 56 , and CD62L ( TQ 1 ) that were directly conjugated to either phycoerythrin ( PE ) and / or fluorescein isothiocyanate ( FITC ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Our results show that together with the CD 117 and IgE characteristic markers , at diagnosis BM MC showed strong expression of CD11c , CD 13 , CD 29 , CD 33 , CD 44 , CD 45 , CD 63 , and CD 71 , and they were also positive for CD 2 , CD 22 , CD 25 , and CD 54 although at a lower level . ^^^ In turn , clinical relapse was related to increased numbers of PB and BM MC together with lower CD 2 , CD11c , CD 45 , and and CD 54 expression and a higher reactivity for the CD 117 and CD 25 antigens . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The levels of expression of the CD 2 , CD 3 , CD 4 and CD 28 antigens were similar ; however , CD 45 and CD45RA antigen expression were slightly lower in cord cells . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Engagement of the CD 45 receptor enhances IL 10 release and proliferation of CD 2 triggered CD45RO+ PBL T . ^^^ The differential responsiveness of LPL T , compared with PBL T , to CD 45 engagement demonstrates that CD 45 could be involved in the altered CD 2 reactivity of LPL T . . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Monoclonal antibodies ( MCAB ) against antigens CD 1 , CD 2 , CD 3 , CD 4 , CD 8 , CD 10 , CD 19 , CD 20 , CD 30 , CD 45 , CD 56 , BLA 36 were used for differentiating lymphoid cells . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Using locus specific probes for CD 2 , CD 4 , CD8alpha , CD 19 , CD 45 , and lambda 5 genes , we show that transcriptionally inactive but not transcriptionally active genes associate with Ikaros heterochromatin foci . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| These cells expressed class 1 and class 2 MHC , CD1a , CD 2 , CD 4 , CD11c , CD 40 , CD 45 , CD 80 , CD 83 , and CD 86 and were potent stimulators of allogeneic T cell activation . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The biopsy specimen showed angiocentric infiltrates of small to medium sized cells positive for CD 4 , CD 45 , and CD 56 but negative for CD 2 , surface and cytoplasmic CD 3 , CD 8 , CD 20 , and CD 57 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| This activatory property was not shared by any other costimulatory molecule expressed by the K14B06 T cell clone , including CD 8 , CD 28 , CD 45 , CD 69 , or CD 2 Ags . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| A small fraction of rat 13 day old fetal liver ( r13FL ) cells , which weakly expressed the leukocyte common antigen CD 45 , constituted a homogeneous Thy 1 ( hi ) , CD 71 ( ) , CD 44 ( + ) , MHC class I+ , CD 43 ( + ) cell subpopulation negative for CD45RC , CD 3 , TCRalphabeta , TCRgammadelta , CD 2 , CD 5 , CD 4 , CD 8 , CD 25 , CD 28 , NKR P1a and sIg . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| They expressed intermediate density CD 45 , as is characteristic of blasts ; in addition , the cells were positive for HLA DR , CD 2 , CD 4 , and the NK associated antigen CD 56 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| We have identified a rare ( approximately 0 . 05 0 . 1 % ) population of cells ( Thy 1 ( hi ) CD 16 ( + ) CD 44 ( hi ) CD 2 ( ) TCRalphabeta ( ) B 220 ( ) M ac 1 ( ) NK 1 . 1 ( ) ) in the adult mouse bone marrow that generates CD 4 ( + ) and CD 8 ( + ) TCRalphabeta ( + ) T cells after tissue culture for 48 hr in the presence of Ly 5 congenic marrow cells . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Histological analysis of an inguinal lymph node showed complete destruction by a diffuse pleomorphic lymphoid proliferation , which was positive for CD 2 , CD 3 , CD 43 , CD 45 , TIA 1 and granzyme B , and displayed a gammadelta phenotype ( deltaTCR1+ , Vdelta1+ , Vdelta 2 , Vdelta 3 , betaF 1 ) . ^^^ Phenotype showed positivity for CD 2 , CD 3 , CD 45 and TIA 1 and expression of gammadelta TCR ( deltaTCR1+ , deltaV1+ , deltaV 2 , deltaV 3 , betaF 1 ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| A three color flow cytometric analysis was performed and revealed two different CD 45 dim , CD 34 ( + ) , CD 117 ( + ) , CD 56 ( + ) immature subpopulations : the normal immature myeloid precursor and an immature blast cell population that expressed CD 41 , CD 42 , CD 61 , CD 36 , CD 13 , CD1a , and CD 2 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| These cells express the T cell antigens CD 2 and CD 5 on their surface , but not CD 7 , and they express CD 4 and CD 45 at numbers of molecules per cell typical for T lymphocytes . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Lymphoma cells expressed the gd T cell receptor ( TCR ) , CD 2 , CD 3 , CD 5 , CD 7 , CD 38 , CD 45 , CD 161 ( NKR P 1 ) , TIA and Ki 67 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Leucocyte number and viability were essentially unchanged from freshly obtained blood , but the expression of cell surface lymphocyte activation antigens ( CD 3 , CD 4 , CD 28 , CD 2 , CD 45 ) decreased rapidly within the first 24 h and continued to fall to less than 20 % of original levels by d 9 of storage at 4 degrees C . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| A 72 year old Caucasian man presented with a malignant neoplasm comprised of blastoid cells without azurophilic granules in the Giemsa stain , with positivity for CD 2 , CD 4 , HLA DR , CD 45 and CD 56 , and negativity for CD 3 ( surface and cytoplasmic ) and CD 5 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Skin biopsies were taken at the same time points , fixed , sectioned , and stained with Giemsa for histologic evaluation , or with mouse anti swine monoclonal antibodies ( CD 1 , CD 2 , CD 4 , CD 5 , CD 8 , CD 25 , CD 45 , MHCII ) and with one mouse anti human monoclonal antibody ( CD62E ) cross reacting with swine for immunohistochemical evaluation . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Expression of some leukocyte antigens ( including CD 45 ) and its isoforms ( CD 2 , CD 4 , CD 5 , CD 6 , CD 7 , and CD 8 ) was examined in the human periapical granulation tissue samples in the present study . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| In an attempt to identify novel diagnostic markers for mast cell ( MC ) proliferative disorders , serial bone marrow ( bm ) sections of 22 patients with mastocytosis ( systemic indolent mastocytosis , n = 19 ; mast cell leukemia [ MCL ] , n = 1 ; isolated bm mastocytosis , n = 2 ) were analyzed by immunohistochemistry using antibodies against CD 2 , CD 15 , CD 29 , CD 30 , CD 31 , CD 34 , CD 45 , CD 51 , CD 56 , CD68R , CD 117 , HLA DR , bcl 2 , bcl 10 ( L ) , myeloperoxidase ( MPO ) , and tryptase . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The cell surface markers CD 2 , CD 3 , CD 4 , CD 7 , CD 8 , CD 19 , and CD 45 were studied for the lymphocyte sub population analysis . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Inhibition of CD 2 CD58 interaction markedly affected segregation of CD 2 and CD2AP from CD 45 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| His tumor showed extensive coagulative necrosis with angioinvasion by large lymphoma cells expressing CD 2 , CD 8 , CD 16 , CD 43 , CD 45 , CD45RO , CD 56 , T cell intracellular antigen 1 , and granzyme B , but not CD 3 , CD 4 , CD 20 , CD 57 , CD 68 , and betaF 1 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Inhibition of CD 45 splicing by dbcAMP was not reverted by addition of exogenous IL 2 . cAMP primed CD45RA cells had a phenotype characteristic of memory / effector T lymphocytes , as they showed an up regulated expression of CD 2 , CD 44 , and CD11a molecules , while the levels of CD62L Ag were down regulated . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| In contrast , ZAP 70 is not required for clustering of zeta GFP and CD 2 or exclusion of CD 45 and CD 43 from the synapse . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| At diagnosis , five year nonsurvivors showed increased patient age and higher concentration of cells in the analyzed specimen , as well as increased levels of % CD 2 , CD 4 , CD 13 , CD 36 , and CD 45 positive AML blasts . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Monoclonal antibodies to porcine CD 1 , CD 2 , CD 4 , CD 8 , CD 45 and IgM were used for immunohistochemical staining . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Changes in leukocyte subpopulations in the blood of the calves were detected both with routine haematological methods and by FCM using specific monoclonal antibodies directed against CD 14 , CD 45 , CD 2 , CD 4 , CD 8 and WC 4 ( a specific surface marker for bovine B lymphocytes ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| In one case , the CD4+ / CD10+ population lacked surface signals of CD 3 and CD 7 , but strongly expressed CD 2 , whereas CD 45 expression was very weak ; partial loss of surface CD 3 was observed in the other . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The immunoprofile of the cells was positive for CD 45 , HLA DR , CD 30 and negative for EMA , CD 34 , CD 38 , CD 2 , CD 3 , CD 4 , CD 7 , CD 8 , CD 10 , CD 15 , CD 19 and CD 20 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| This synapse is characterized by an enrichment for phosphotyrosine , CD 2 , and gammadelta TCR together with the exclusion of CD 45 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| We report here an optimized , rapid negative isolation method that depletes umbilical cord blood ( UCB ) mononucleated cells ( MNC ) from cells expressing hematopoietic markers ( CD 45 , glycophorin A , CD 38 , CD 7 , CD 33 , CD 56 , CD 16 , CD 3 , and CD 2 ) and isolates a discrete lineage negative ( Lin ) cell population ( 0 . 10 % + / 0 . 02 % MNC , n=12 ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The immature cells ( double positive ) expressed CD 2 , CD 5 , CD 7 , CD 4 , CD 8 , heterogeneous surface CD 3 , and intermediate density CD 45 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| RESULTS : HR 8348 cell line did not express CD 2 , CD 3 , CD 4 , CD 5 , CD 7 , CD 8 , TCR , CD 10 , CD11b , CD 14 , CD 16 , CD 19 , CD 22 , CD 25 , CD 28 , SmIg , CD 33 , CD 35 , CD 36 , CD41a , CD 45 , CD45RA , CD45RO , CD 56 , CD 61 , CD 64 , CD66b , CD 69 , CD 71 , CD 117 , CD 122 and P glycoprotein but expressed CD 13 , CD 15 , CD 20 , CD 38 , CD 95 and HLA DR . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| M3v APLs ( n = 30 ) had more leukemic promyelocytes expressing the T cell antigen , CD 2 ( P < 0 . 0001 ) or the stem cell marker , CD 34 ( P = 0 . 0003 ) and demonstrated higher fluorescence intensity for the binding of antibody to the common leukocyte antigen , CD 45 ( P = 0 . 0008 ) than M 3 ( n = 102 ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| However , they showed unequivocal expression of both CD 30 and CD 15 , and no aberrant antigen expression to suggest ALCL ( BSAP+ , EMA , LCA , CD 43 , CD 2 , CD 3 , CD 4 , CD45RO , ALK , granzymeB ) , with negative TCR gene rearrangement and no expression of EBV . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| METHODS : Sequential density gradient centrifugation , depletion of lymphocytes , removal of adherent cells , and negative selection with CD 2 , CD11b , CD 16 , and CD 45 monoclonal antibodies were used to purify day 1 BFU E , which were then incubated for 3 days to generate day 4 cells . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemical staining established the T cell origin of the neoplasm with strong expression of CD 45 , CD 3 , CD 43 , and CD 2 and also showed expression of CD 30 consistent with the histologic features that suggested ALCL . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The first study of the proteome of NK cell GEM revealed several new aspects including identification of molecules not expected to be expressed in rat NK cells ( e . g . , NAP 22 ) or associated with GEM ( e . g . , NKR P 1 , CD 45 , CD 2 ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Several galectin 1 receptors are discussed such as CD 45 , CD 7 , CD 43 , CD 2 , CD 3 , CD 4 , CD 107 , CEA , actin , extracellular matrix proteins such as laminin and fibronectin , glycosaminoglycans , integrins , a beta lactosamine glycolipid , GM 1 ganglioside , polypeptide HBGp 82 , glycoprotein 90 K / MAC 2BP , CA 125 cancer antigen , and pre B cell receptor . . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The tumor cells expressed focal immunocytochemical reactivity to CD 45 and CD 68 , but were negative for CD 2 , CD 3 , CD 4 , CD 8 , CD 20 , CD 30 , CD45RO , epithelial membrane antigen ( EMA ) , cytokeratin , and HMB 45 . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| The virus induced the production of TNF alpha , IL 10 and IL 12 p 70 while inhibited IFN alpha secretion , increased the percentage of CD 2 ( + ) cells while decreased that of CD 4 ( + ) or CD 45 RA ( + ) cells . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| Cases were diagnosed by peripheral blood counts , bone marrow cytology , cytochemistry , cytogenetics and immunophenotyping ( CD 2 , CD 3 , CD 7 , CD 19 , CD 13 , CD 33 , myeloperoxydase MPO , CD 14 , CD 15 , HLA DR , CD 34 , CD 56 and CD 45 ) . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| An extensive series of Mab ( CD 2 , CD 3 , CD 4 , CD 8 , CD11b , CD 13 , CD 14 , CD 16 , CD 19 , CD 22 , CD 33 , CD 34 , CD 41 , CD42b , CD 45 , CD 56 , CD 61 , CD 64 , CD235a and HLA DR ) were tested singly or in FITC / PE combinations . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| In the presence of mouse spleen cells , activated with LcA at a concentration of 12 . 5 microgram / ml , optimal augmentation of the humoral immune response to sheep erythrocytes ( SRBC ) was observed . ^^^ |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06729 and P08575 |
Pubmed |
SVM Score :0.0 |
| NA |
|