| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| Inhibition of CDK 1 deactivation similarly caused aurora B to remain associated with centromeres during anaphase . ^^^ Our results suggest that microtubules , CDK 1 , and the kinase activity each play a distinct role in the dynamics and functions of aurora B in dividing cells . . ^^^ |
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| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| Upon mitotic entry , Scc 2 is removed from chromatin through a mechanism that requires cdc 2 but not aurora B or polo like kinase . ^^^ |
|
| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| This mutant can bind not only other Hsp 90 client protein kinases , Akt 1 , Aurora B and Cdk 4 , but also Cdc 2 and Cdk 2 , which to date have not been shown to physically interact with Cdc 37 . ^^^ |
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| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| Mitotic chromosomal dynamics is regulated by the coordinated activities of many mitotic kinases , such as cyclin dependent kinase 1 ( Cdk 1 ) , Aurora B or Polo like kinase 1 ( Plk 1 ) , but the mechanisms of their coordination remain unknown . ^^^ Here , we report that Cdk 1 phosphorylates Thr 59 and Thr 388 on inner centromere protein ( INCENP ) , which regulates the localization and kinase activity of Aurora B from prophase to metaphase . ^^^ We propose that INCENP phosphorylation by Cdk 1 is necessary for the recruitment of Plk 1 to the kinetochore , and that the complex formation of Plk 1 and Aurora B on INCENP may play crucial roles in the regulation of chromosomal dynamics . . ^^^ |
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| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| IF phosphorylation by Cdk 1 , Plk 1 , Rho kinase and Aurora B plays an important role in the local IF breakdown , and is essential for the efficient segregation of IF networks into daughter cells . ^^^ |
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| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| The novel serine / threonine kinases , designated STK 1 and STK 2 , were homologous to the human cdc 2 and the Aspergillus nimA genes . ^^^ |
|
| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q96GD4 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|