| Interacting proteins: Q92574 and P06493 |
Pubmed |
SVM Score :0.0 |
| Cell cycle regulated phosphorylation of hamartin , the product of the tuberous sclerosis complex 1 gene , by cyclin dependent kinase 1 / cyclin B . ^^^ In vitro assays showed that cyclin dependent kinase 1 phosphorylates hamartin at three sites , one of which ( Thr 417 ) is in the hamartin tuberin interaction domain . ^^^ Hamartin with alanine mutations in the three cyclin dependent kinase 1 phosphorylation sites increased the inhibition of p70S6 kinase by the hamartin tuberin complex . ^^^ |
|
| Interacting proteins: Q92574 and P06493 |
Pubmed |
SVM Score :0.0 |
| Phosphorylation of hamartin ( TSC 1 ) by CDK 1 also negatively regulates the activity of the hamartin / tuberin complex . ^^^ |
|
| Interacting proteins: Q92574 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|