| Interacting proteins: P24385 and P06493 |
Pubmed |
SVM Score :0.0 |
| DNA microarray analysis of livers from ET 743 treated animals showed a dramatic increase in the expression of ATP binding cassette transport genes Abcb1a and Abcb1b , which impart resistance to anticancer drugs , and of Cdc2a and Ccnd 1 , the rodent homologues of human cell cycle genes CDC 2 and cyclin D 1 , respectively . ^^^ |
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| Interacting proteins: P24385 and P06493 |
Pubmed |
SVM Score :0.0 |
| We show by gene expression profiling that activation of the GLI 2 oncogene in human keratinocytes activates the transcription of a number of genes involved in cell cycle progression such as E2F1 , CCND 1 , CDC 2 and CDC45L , while it represses genes associated with epidermal differentiation . ^^^ |
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| Interacting proteins: P24385 and P06493 |
Pubmed |
SVM Score :0.0 |
| This analysis predicts that cancer cells manifesting a stem cell like expression profile of a death from cancer signature would exhibit the following features : a concomitantly increased expression of certain members of inhibitor of apoptosis protein ( IAP ) family ( Survivin and XIAP ) ; activation of mitotic spindle check point proteins ( BUB 1 , BUB 3 , KNTC 2 , Mad 2 , PLK 1 , PLK 4 , STK6 / Aurora A ) ; and elevated levels of certain cell cycle control / marker proteins ( CCNB 1 , CCNB 2 , CCND 1 , CCNA 2 , CDC 2 , CDC 25 , Ki 67 , USP 22 ) . ^^^ |
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| Interacting proteins: P24385 and P06493 |
Pubmed |
SVM Score :0.0 |
| PRAD 1 encodes a novel type of cyclin protein and thus may normally function in controlling the cell cycle , perhaps through direct interaction with cdc 2 or a related kinase . ^^^ |
|
| Interacting proteins: P24385 and P06493 |
Pubmed |
SVM Score :0.0 |
| Addition of the PRAD 1 protein to interphase clam embryo lysates containing inactive p34cdc2 kinase and lacking endogenous cyclins allows it to be isolated using beads bearing p13suc1 , a yeast protein that binds cdc 2 and related kinases with high affinity and coprecipitates kinase associated proteins . ^^^ Addition of PRAD 1 also induces phosphorylation of histone H 1 , a preferred substrate of cdc 2 . ^^^ |
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| Interacting proteins: P24385 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P24385 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P24385 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P24385 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|