| Interacting proteins: O43683 and P06493 |
Pubmed |
SVM Score :0.0 |
| Leukemias with a 5 / del ( 5q ) have a higher expression of genes involved in cell cycle control ( CCNA 2 , CCNE 2 , CDC 2 ) , checkpoints ( BUB 1 ) , or growth ( MYC ) , and loss of expression of the gene encoding IFN consensus sequence binding protein ( ICSBP ) . ^^^ |
|
| Interacting proteins: O43683 and P06493 |
Pubmed |
SVM Score :0.0 |
| Leukemias with a 5 / del ( 5q ) have a higher expression of genes involved in cell cycle control ( CCNA 2 , CCNE 2 , CDC 2 ) , checkpoints ( BUB 1 ) , or growth ( MYC ) , and loss of expression of the gene encoding interferon consensus sequence binding protein ( ICSBP ) . ^^^ |
|
| Interacting proteins: O43683 and P06493 |
Pubmed |
SVM Score :0.0 |
| The Plk 1 Bub1 interaction requires the polo box domain ( PBD ) of Plk 1 and is enhanced by cyclin dependent kinase 1 ( Cdk 1 ) mediated phosphorylation of Bub 1 at T 609 . ^^^ Our results suggest that phosphorylation of Bub 1 at T 609 by Cdk 1 creates a docking site for the PBD of Plk 1 and facilitates the kinetochore recruitment of Plk1 . . ^^^ |
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| Interacting proteins: O43683 and P06493 |
Pubmed |
SVM Score :0.0 |
| This analysis predicts that cancer cells manifesting a stem cell like expression profile of a death from cancer signature would exhibit the following features : a concomitantly increased expression of certain members of inhibitor of apoptosis protein ( IAP ) family ( Survivin and XIAP ) ; activation of mitotic spindle check point proteins ( BUB 1 , BUB 3 , KNTC 2 , Mad 2 , PLK 1 , PLK 4 , STK6 / Aurora A ) ; and elevated levels of certain cell cycle control / marker proteins ( CCNB 1 , CCNB 2 , CCND 1 , CCNA 2 , CDC 2 , CDC 25 , Ki 67 , USP 22 ) . ^^^ |
|
| Interacting proteins: O43683 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43683 and P06493 |
Pubmed |
SVM Score :0.0 |
| NA |
|