| Interacting proteins: Q9UBU8 and P06400 |
Pubmed |
SVM Score :0.50423107 |
| Rb was associated with MRG 15 and PAM 14 ( a novel coil coil protein ) in MAF 1 , and a histone acetyl transferase , hMOF , was an MRG 15 partner in MAF 2 . 0.50423107^^^ |
|
| Interacting proteins: Q9UBU8 and P06400 |
Pubmed |
SVM Score :0.0 |
| We have shown that MRGX and MRG 15 associate with Rb in nucleoprotein complexes and regulate B myb promoter activity . ^^^ |
|
| Interacting proteins: Q9UBU8 and P06400 |
Pubmed |
SVM Score :0.0 |
| In this regard , we have found that both the retinoblastoma tumor suppressor ( Rb ) and a novel nuclear protein PAM 14 ( Protein Associated with MRG , 14 kDa ) specifically associate with MRG 15 . ^^^ Significantly we have demonstrated that MRG 15 blocks the Rb induced repression of this promoter , leading to B myb promoter activation . ^^^ Collectively these results suggest that MRG 15 regulates transcription through interactions with a cellular protein complex containing Rb and PAM14 . . ^^^ |
|
| Interacting proteins: Q9UBU8 and P06400 |
Pubmed |
SVM Score :0.0 |
| MRG 15 , a closely related family member , is in a complex with the retinoblastoma tumor suppressor protein Rb and activates the B myb promoter , which is tightly controlled by Rb / E2F through the E2F binding site . ^^^ |
|