| Interacting proteins: Q92831 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92831 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92831 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92831 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92831 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92831 and P06400 |
Pubmed |
SVM Score :0.0 |
| Analysis of E1A mutants showed that stimulation of the MMTV promoter is mediated solely through conserved region 3 and does not require interaction with Rb , p300 / CBP associated factor , or CBP / p300 . ^^^ |
|
| Interacting proteins: Q92831 and P06400 |
Pubmed |
SVM Score :0.0 |
| Fibroblast cell lines from 20 retinoblastoma ( RB ) patients with the hereditary bilateral form of disease compared with 16 lines from normal donors had a significantly higher chromatid aberration frequency ( CAF ) , and more displaced and nondisplaced breaks per 100 metaphase cells after 10 irradiation during the G 2 phase of the cell cycle . ^^^ The mean CAF was 39 + / 1 . 0 , range 30 46 , for cells from normal subjects , compared to a mean of 245 . 6 , range 101 506 , for cells from hereditary RB patients ( p < 10 ( 6 ) . ^^^ Of fibroblast lines from eight patients with unilateral RB , four had a CAF comparable to that of lines from normal donors ( < 60 ) and four had a high CAF ( > 130 ) , resembling that of hereditary forms ; two of the latter four lines were from patients with familial or deletion 13 forms of RB . ^^^ Furthermore , in two families , PHA stimulated blood lymphocytes from RB patients , one bilateral and one unilateral , and from certain unaffected first degree relatives after G 2 phase 10 irradiation had a high CAF ( > or = 110 ) compared to a CAF ( > or = 53 ) of cells from three normal donors sampled at the same time . ^^^ |
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