| Interacting proteins: Q13029 and P06400 |
Pubmed |
SVM Score :0.87780798 |
| Also like E1A , RIZ can form a ternary complex with Rb and E2F1 . 0.87780798^^^ |
|
| Interacting proteins: Q13029 and P06400 |
Pubmed |
SVM Score :0.0 |
| The PR domain of the Rb binding zinc finger protein RIZ 1 is a protein binding interface and is related to the SET domain functioning in chromatin mediated gene expression . ^^^ This family includes the MDS 1 EVI1 gene inactivated in myeloid leukemia , the PRDI BF1 / BLIMP1 transcription repressor of c myc involved in driving B cell differentiation , and the RIZ gene , which encodes proteins capable of binding to the retinoblastoma tumor suppressor protein ( Rb ) . ^^^ |
|
| Interacting proteins: Q13029 and P06400 |
Pubmed |
SVM Score :0.0 |
| Consistent with a potential role in the Rb pathway , RIZ may play an important role in human cancer pathogenesis . ^^^ |
|
| Interacting proteins: Q13029 and P06400 |
Pubmed |
SVM Score :0.0 |
| Methylation profile was analyzed in nine cases of relapsed childhood acute lymphoblastic leukemia ( ALL ) for p 14 , p 15 , p 16 , Rb , MGMT , APC , hMLH 1 , RARbeta , RIZ , DAPK , and FHIT genes by using methylation specific polymerase chain reaction ( MSP ) analysis . ^^^ None of the p 14 , p 15 , Rb , APC , hMLH 1 , RIZ , DAPK , and FHIT genes were hypermethylated . ^^^ |
|
| Interacting proteins: Q13029 and P06400 |
Pubmed |
SVM Score :0.0 |
| Four genes ( p 15 , p 16 , RARbeta , FHIT ) had methylation in both diseases , four genes ( p 14 , Rb , MLH 1 , DAPK ) showed no methylation in both diseases , and the two genes ( APC , RIZ ) demonstrated methylation only in adult ALL . ^^^ |
|
| Interacting proteins: Q13029 and P06400 |
Pubmed |
SVM Score :0.0 |
| The Rb interacting zinc finger gene RIZ 1 is commonly mutated in MSI ( + ) colorectal , gastric , and endometrial cancers and has demonstrated a capacity to induce cell cycle arrest and apoptosis . ^^^ |
|
| Interacting proteins: Q13029 and P06400 |
Pubmed |
SVM Score :0.0 |
| Methylation profile was analyzed in eleven cases of therapy related leukemia ( t leukemia ) for p 14 , p 15 , p 16 , Rb , hMLH 1 , hMSH 2 , MGMT , APC , RAR beta , DAPK , RIZ 1 , FHIT , and SOCS 1 genes by using methylation specific polymerase chain reaction ( MSP ) analysis . ^^^ |
|
| Interacting proteins: Q13029 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13029 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|