| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.82706147 |
| The protein encoded by the 5 cyclin gene of this oncogenic herpesvirus was found to have an apparent molecular size of 29 kDa in transformed cells . 5 Cyclin protein was found to be associated with cdk 6 , a cellular cyclin dependent kinase known to interact with cellular type D cyclins . cdk6 / v cyclin complexes strongly phosphorylated Rb fusion protein and histone H 1 as substrates in vitro . 0.82706147^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Since most hematological malignancies except ALL are infrequently associated with p16INK4A and retinoblastoma ( Rb ) gene alteration it seems worthwhile to explore cdk 4 and cdk 6 expression to determine whether or not the disruption of the p16INK4A / Rb / cdk4 / cdk6 regulatory loop might play a role in their pathogenesis . . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| D type cyclins , in association with the cyclin dependent kinases Cdk 4 or Cdk 6 , promote progression through the G 1 phase of the cell cycle by phosphorylating the retinoblastoma protein ( RB ) . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| D type cyclins , in association with the cyclin dependent kinases Cdk 4 or Cdk 6 , regulate events in the G 1 phase of the cell cycle and may contribute to the phosphorylation of the retinoblastoma gene product ( Rb ) . ^^^ However , in cells in which the function of Rb has been compromised , either by naturally arising mutations or through binding to proteins encoded by DNA tumour viruses , Cdk 4 and Cdk 6 are not associated with D cyclins . ^^^ Since Rb negative cells express high levels of p 16 , we suggest that in these cells p 16 competes with D cyclins for binding to Cdk 4 and Cdk 6 and prevents formation of active complexes . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Multiple mechanisms of p16INK4A inactivation in non small cell lung cancer cell lines . p16INK4A , a specific inhibitor of cyclin dependent kinase ( cdk ) 4 and cdk 6 , is a candidate tumor suppressor in malignancies with wild type retinoblastoma ( Rb ) . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| In the glioblastomas with no alterations of CDKN2A , CDK 4 or RB 1 , several other genes ( CCND 1 , CCND 2 , CCND 3 , CDK 6 , E2F , CDK 7 , MYC and MYCN ) whose products take part in cell cycle regulation were examined . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| The cyclin D dependent kinases CDK 4 and CDK 6 trigger phosphorylation of the retinoblastoma protein ( RB ) late in G 1 phase , helping to cancel its growth suppressive function and thereby facilitating S phase entry . ^^^ Although specific inhibition of cyclin D dependent kinase activity in vivo can prevent cells from entering S phase , it does not affect S phase entry in cells lacking functional RB , implying that RB may be the only substrate of CDK 4 and CDK 6 whose phosphorylation is necessary for G 1 exit . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| An obvious focus is the so called restriction point in late G 1 , and current evidence suggests that this is in part determined by the phosphorylation of the retinoblastoma protein ( Rb ) by the cyclin D dependent kinases , CDK 4 and CDK 6 . ^^^ Downstream targets of Rb , such as the E2F1 transcription factor , can promote cell cycle progression , whereas inhibitors of CDK 4 and CDK 6 , such as p16CDKN2a , can block G 1 progression . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| To determine a possible mechanism by which senescent human fibroblasts maintain a hypophosphorylated Rb , we examined the expression levels and interaction of the Rb kinases , CDK 4 and CDK 6 , and the cyclin dependent kinase inhibitors p 21 and p 16 in senescent HDFs . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| On the other hand , there was no significant difference in expression of proteins such as Rb , p 16 , cdk 4 , cdk 6 , cyclin A and cyclin D 1 between the normal and immortalized human fibroblasts . . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| GR activation in U2OS cells represses expression of the cyclin dependent kinases ( CDKs ) CDK 4 and CDK 6 as well as their regulatory partner , cyclin D 3 , leading to hypophosphorylation of the retinoblastoma protein ( Rb ) . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| When stimulated by a combination of PHA and anti CD 28 mAb , cdk 6 activity was up regulated , as measured by an in vitro kinase assay using recombinant , truncated retinoblastoma tumor suppressor gene protein ( Rb protein ) as substrate . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Analysis of expression of genes regulating Rb phosphorylation revealed that activin A suppressed cyclin D 2 , the sole D type cyclin gene expressed in the hybridoma cells , and activated p21CIP1 / WAF1 but had no effect on expression of cyclin dependent kinases ( CDK 2 , CDK 4 , CDK 6 ) and other CDK inhibitors ( p27KIP1 , p16INK4a , p15INK4b ) . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| A cdk 2 inhibitor , Olomoucine , as well as a dominant negative cdk 2 construct prevented HLA class 1 mediated inactivation of Rb ; in contrast , dominant negative cdk 4 and cdk 6 constructs had no effect . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| These include mutation and / or deletion of the retinoblastoma ( RB 1 ) gene , homozygous deletion of the CDKN2A and CDKN2B genes , as well as amplification and overexpression of the CDK 4 and CDK 6 genes . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Cellular signal transduction cascades triggered by mitogenic or antiproliferative cues eventually converge on a biochemical mechanism centered around the retinoblastoma tumor suppressor ( pRb ) , the so called RB pathway that governs G 1 phase progression and guards the commitment to enter S phase . pRb , together with its immediate upstream regulators , the D type cyclins , their partner cyclin dependent kinases Cdk 4 and Cdk 6 , and the Cdk inhibitors , form a functional unit that is involved in major decisions about cellular fate , and whose components , including the proto oncogenic cyclin D dependent kinases , are commonly deregulated in many types of cancer . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Failure of T lymphocytes from elderly humans to enter the cell cycle is associated with low Cdk 6 activity and impaired phosphorylation of Rb protein . ^^^ In the same cell preparations , in vitro phosphorylation of recombinant truncated Rb protein by immunoprecipitated Cdk 6 was significantly decreased . ^^^ The low Cdk 6 activity observed in T lymphocytes from the elderly was associated with a defective phosphorylation of the endogenous Rb protein and an increased sequestration of the E ( 2 ) F 1 transcription factor , possibly resulting in early cell cycle arrest . . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| In the same cells , a decrease in the phosphorylated form of Rb protein and an increase in the p 130 protein were observed without changes in the protein level of cell cycle dependent kinase 2 ( Cdk 2 ) , Cdk 4 , and Cdk 6 . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Furthermore , the activity of CDK 6 associated kinase was reduced in association with hypophosphorylation of Rb protein . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Mitogen dependent , cyclin D dependent kinases ( cdk 4 and cdk 6 ) phosphorylate the retinoblastoma ( Rb ) tumor suppressor protein , helping to cancel its growth inhibitory effects and enabling E2F transcription factors to activate genes required for entry into the DNA synthetic phase ( S ) of the cell division cycle . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Rb phosphorylation is mediated by cyclin dependent kinases ( CDKs ) , whose activity is enhanced by cyclins and inhibited by CDK inhibitors . p 16 ( INK4A ) is a member of a family of inhibitors specific for CDK 4 and CDK 6 . p 16 ( INK4A ) is deleted and inactivated in a wide variety of human malignancies , including familial melanomas and pancreatic carcinoma syndromes , indicating that it is an authentic human tumor suppressor . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Low levels of cyclin D and nonfunctional Rb protein affect cdk 6 association with cyclin dependent kinase inhibitor p 27 ( Kip 1 ) . p 27 ( Kip 1 ) associates with cyclin / cdk complexes and inhibiting cdk activity , and overexpression of p 27 ( Kip 1 ) induces G 1 arrest . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| To avoid the confounding pleiotropic effects of HPVE 7 frequently used in such studies , here we have employed retroviral vectors over expressing CDK 4 or CDK 6 as a more representative model of naturally occurring mutations targeting the Rb pathway . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Furthermore , the activities of CDK 2 and CDK 6 associated kinases reduced by monensin were associated with hypophosphorylation of Rb protein . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Genes examined included the retinoblastoma susceptibility gene ( Rb 1 ) ; cyclins D 1 , D 2 , A , and E ; the CDK inhibitors p 18 , p 19 , and p 27 ; CDK 2 and CDK 6 ; transcription factors E2F 4 , E2F 5 , and DP 1 ; and the neurofibromatosis type 2 gene . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| A multiparametric analysis identified proteins associated with increased growth fraction ( Hdm 2 , p 53 , p 21 , Rb , cyclins A , B 1 , D 3 , and E , CDK 2 , CDK 6 , SKP 2 , Bcl 10 ( L ) , survivin , STAT 1 , and STAT 3 ) , and proteins associated with apoptosis ( NF kappaB , STAT 1 , and RB ) . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| D type cyclins bind to and activate the cyclin dependent kinases Cdk 4 and Cdk 6 , which in turn phosphorylate their downstream target , the retinoblastoma protein Rb . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| In addition , the activities of CDK 2 and CDK 6 associated kinase were reduced in association with hypophosphorylation of Rb protein . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Furthermore , the activities of CDK 2 , CDK 4 and CDK 6 associated kinase were reduced in association with hypophosphorylation of Rb protein . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Moreover , UV induced melanomas showed a strict reciprocal relationship between cdk 6 amplification and p 16 ( INK4a ) loss , which is consistent with the actions of UV along the Rb pathway . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| The INK 4 family of cyclin dependent kinase ( CDK ) inhibitors negatively regulates cyclin D dependent CDK 4 and CDK 6 and thereby retains the growth suppressive function of Rb family proteins . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Furthermore , the activities of CDK 2 and CDK 6 associated kinase were reduced in association with hypophosphorylation of Rb protein . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Furthermore , the activities of CDK 2 , CDK 4 and CDK 6 associated kinase were reduced and the lack of the CDK activity was paralleled by increased hypophosphorylation of Rb protein . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Furthermore , the activities of CDK 2 and CDK 6 associated kinases were reduced in association with hypophosphorylation of Rb protein . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Furthermore , the retinoblastoma protein ( Rb ) , a substrate of CDK 2 and CDK 6 , whose phosphorylation is necessary for cell cycle progression , becomes hypophosphorylated . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| This effect was accompanied by the decreased expression of G ( 1 ) associated proteins including cyclin D 1 , CDK 4 , and Rb phosphorylation at Ser 780 , Ser 795 , and Ser807 / 811 , whereas expression of CDK 6 and beta actin was not affected by LY 294002 . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Cyclin dependent kinase 4 ( Cdk 4 ) and Cdk 6 , and later Cdk 2 , in association with their specific cyclin partners , regulate the G 1 to S phase cell cycle transition of mammalian cells by phosphorylation of retinoblastoma ( Rb ) family proteins . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Cell lines with restored cdk 6 levels accumulated higher amounts of the Rb family protein p 130 as well as E2F4 , a suppressing member of the E2F family of transcription factors , in their nuclei . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| In addition , saucernetin 7 markedly enhanced the binding of p21CIP1 / WAF1 with CDK 2 and CDK 6 , resulting in the reduced activity of both kinases and the hypophosphorylation of Rb protein . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| In rasREF cells treated with DE for 72 h in suspension culture ( a ) , the levels of cyclin D 1 , cyclin A , p 27 ( Kip 1 ) , and hyperphosphorylated Rb were decreased , but the levels of cdk 4 , cdk 6 , cdk 2 , p 16 ( INK4a ) , and p 21 ( Cip 1 ) were not affected . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Cyclin D 1 , D 2 and D 3 , and Cdk 4 , Cdk 6 and Rb protein , and Cyclin D 1 mRNA expression were measured in primary patient derived neuroblastoma cell lines . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| The p16INK4a tumor suppressor protein functions as an inhibitor of CDK 4 and CDK 6 , the D type cyclin dependent kinases that initiate the phosphorylation of the retinoblastoma tumor suppressor protein , RB . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Indeed , this phosphorylation was observed 6 hours after p 25 induction and was abolished in the presence of a Cdk 5 inhibitor , roscovitine , which does not inhibit the usual Rb cyclin D kinases Cdk 4 and Cdk 6 . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Cells exposed to 17 AAG and LY 294002 displayed a significant reduction in cell cycle regulatory proteins , such as retinoblastoma ( Rb ) , cyclin dependent kinase ( CDK ) 4 , CDK 6 , cyclin D 1 , and cyclin D 3 . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| After analyzing the cellular proteins involving in regulation of cell cycle progression , we demonstrated that ORF7a expression was correlated with a significant reduction of cyclin D 3 level of mRNA transcription and expression , and phosphorylation of retinoblastoma ( Rb ) protein at ser 795 and ser809 / 811 , not with the expression of cyclin D 1 , D 2 , cdk 4 and cdk 6 in HEK 293 cells . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Furthermore , increased protein levels of PPM1D and CDK 6 may link the TP 53 and RB 1 tumor suppressor pathways to medulloblastoma pathomechanisms . . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Cyclin D 1 or D 3 expression does not vary in the clinical course , but that alone is insufficient to promote cell cycle progression unless cyclin dependent kinase 4 ( cdk 4 ) is also elevated , in the absence of cdk 6 , to phosphorylate the retinoblastoma protein ( Rb ) . ^^^ By contrast , cyclin D 2 and cdk 6 are coordinately increased , thereby overriding the inhibition by cdk inhibitors p 18 ( INK4c ) and p 27 ( Kip 1 ) and phosphorylating Rb in conjunction with the existing cdk 4 . ^^^ In addition , cyclin D 1 or cyclin D 3 expressing multiple myeloma cells are uniformly distributed in the bone marrow , whereas cdk 6 specific phosphorylation of Rb occurs in discrete foci of bone marrow multiple myeloma cells before proliferation early in the clinical course and is then heightened with proliferation and disease progression . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| In Myc deficient cells , despite its inability to overcome this proliferation block , 5 Src was able to regulate the expression of certain Myc transcriptional targets and induce the expression of active cyclin D / Cdk4 and Cdk 6 complexes ; it also induced the phosphorylation of Rb , albeit at reduced levels . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemical stains were carried out on tissue microarrays to evaluate the expression of proteins involved in the G ( 1 ) S transition and proteins that regulate apoptosis including Rb , E2F1 , cyclin D 1 , CDK 4 , CDK 6 , p 27 ( KIP 1 ) , p 21 ( WAF1 / CIP1 ) , p 53 , Mdm 2 , Bcl 2 , and Bax . ^^^ The positive phenotypes identified were as follows : Rb , 39 . 1 % ; E2F1 , 69 . 6 % ; cyclin D 1 , 30 . 4 % ; CDK 4 , 100 % ; CDK 6 , 30 . 4 % ; 39 . 1 % ; p 27 ( KIP 1 ) , 47 . 8 % ; p 21 ( WAF1 / CIP1 ) , 39 . 1 % ; p 53 , 43 . 5 % ; Mdm 2 , 17 . 4 % ; Bcl 2 , 91 . 3 % ; and Bax , 100 % . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| Membrane depolarization induced by 50 mM KCl for 5 min significantly increased SH SY5Y cell numbers and thymidine incorporation at 24 h after depolarization , and increased the phosphorylation and expression of retinoblastoma protein ( RB ) , the activity of Cdk 2 ( without changing the activities of Cdk 4 and Cdk 6 ) , and the expressions of cyclin A and cyclin E . ^^^ |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|