| PRMT 2 directly bound and interacted with RB through its AdoMet binding domain , in contrast to other PRMT proteins , including PRMT 1 , PRMT 3 and PRMT 4 . 1.1659761^^^ Here , we show that RB interacts with PRMT 2 , a member of the protein arginine methyltransferase family , to regulate E2F activity . 0.87112366^^^ |