| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| Despite its requirement for apoptosis in vitro , mutation in Casp 9 abrogated cell death in the nervous system and lens but only partly in skeletal muscles of Rb deficient embryos . ^^^ Deregulation of the Rb pathway by overexpression of E2F1 also induced caspase 9 dependent , Apaf 1 independent apoptosis in myoblasts . ^^^ |
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| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| Deregulation of the Rb E2F repressor complex by genetic deletion or functional inhibition of Rb triggers apoptosis through both the intrinsic ( caspase 9 mediated ) and extrinsic ( caspase 8 mediated ) death pathways . ^^^ |
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| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| Caspase 9 can antagonize p 53 induced apoptosis by generating a p 76 ( Rb ) truncated form of Rb . ^^^ We also provide evidence that the involvement of caspase 9 in a pre mitochondrial protective pathway results from the previously undescribed cleavage of Rb , at a LExD site , into a p 76 ( Rb ) form , which antagonizes p 53 induced apoptosis . ^^^ |
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| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55211 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|