| Interacting proteins: P35869 and P06400 |
Pubmed |
SVM Score :0.83288319 |
| Coimmunoprecipitation of whole cell lysates from human breast carcinoma MCF 7 cells , which express both proteins endogenously , revealed that AHR associates with RB in vivo only after receptor transformation and nuclear translocation . 0.83288319^^^ |
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| Interacting proteins: P35869 and P06400 |
Pubmed |
SVM Score :0.0 |
| Since RB signaling to Cdk 2 is disrupted in these tumor cells , we co expressed two proteins that cooperate with RB in transcriptional repression , AHR and BRG 1 , in an attempt to correct this signaling dysfunction . ^^^ Co expression of AHR / BRG 1 with PSM RB attenuated Cyclin A and Cdk 2 expression as well as Cdk 2 associated kinase activity , resulting in cell cycle inhibition of C33A cells . ^^^ Importantly , ectopic expression of Cyclin A was able to reverse the arrest mediated by co expression of AHR / BRG 1 with PSM RB . ^^^ |
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| Interacting proteins: P35869 and P06400 |
Pubmed |
SVM Score :0.0 |
| In this Prospect , we discuss the involvement of the AHR in pathways critical to cell cycle regulation , mitogen activated protein kinase cascades , immediate early gene induction , and the functions of the RB protein . ^^^ |
|
| Interacting proteins: P35869 and P06400 |
Pubmed |
SVM Score :0.0 |
| DMBA induced mammary tumors exhibited elevated expression of the aryl hydrocarbon receptor ( AhR ) , c myc , cyclin D 1 , and hyperphosphorylated retinoblastoma ( Rb ) protein . ^^^ |
|
| Interacting proteins: P35869 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35869 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35869 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|