| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| In addition , we detected expression of a full length RBL1 / p107 and RBL2 / p130 species in every sample tested ( RBL 1 or RBL 2 inactivation in 0 / 69 ) and confirmed that both RB related gene products retain functional binding activity to the E1A viral oncoprotein . ^^^ Although we detected a faint 85 kDa protein species using specific anti Tag antibodies , this signal migrated slightly faster than Tag extracted from Cos 7 cells and did not exhibit binding activity to the RB or RBL 1 proteins . ^^^ While the RB / p16 tumor suppressor pathway is targeted for mutations in 100 % of lung cancers , mutational inactivation of the related RBL 1 and RBL 2 genes is a rare event . . ^^^ |
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| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| Here , we report a connection between the members of the retinoblastoma family of proteins , Rb 1 ( retinoblastoma 1 ) , Rbl 1 ( retinoblastoma like 1 ) and Rbl 2 ( retinoblastoma like 2 ) , and the mechanisms that regulate telomere length . ^^^ In particular , mouse embryonic fibroblasts doubly deficient in Rbl 1 and Rbl 2 or triply deficient in Rbl 1 , Rbl 2 and Rb 1 have markedly elongated telomeres compared with those of wildtype or Rb 1 deficient cells . ^^^ |
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| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| Mouse embryonic fibroblasts that are triply deficient for RB 1 ( retinoblastoma 1 ) , RBL 1 ( retinoblastoma like 1 ) and RBL 2 ( retinoblastoma like 2 ) known as TKO cells show a marked genomic instability , which is coincidental with decreased DNA methylation , increased acetylation of histone H 3 and decreased tri methylation of histone H 4 at lysine 20 ( H4K20 ) . ^^^ |
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| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| This review will focus on the role of the pocket proteins ( PPs ) , Rb 1 ( retinoblastoma protein ) , retinoblastoma like 1 ( Rbl 1 also known as p 107 ) and retinoblastoma like 2 ( Rbl 2 also known as p 130 ) , in melanocyte homeostasis , with particular emphasis on their functions in the cell cycle and the DNA damage repair response . ^^^ |
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| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| RB , the most investigated tumor suppressor gene , is the founder of the RB family of growth / tumor suppressors , which comprises also p 107 ( RBL 1 ) and Rb2 / p130 ( RBL 2 ) . ^^^ |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P28749 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|