| The results showed that FYN and LT could lower the pulmonary artery pressure ( PAP ) significantly ; decrease the pulmonary vascular resistance ( PVR ) as well as the consumption of oxygen in cardiac muscle ; increase cardiac output ( CO ) ; improve some indices in hemorrheology ; while PaO 2 and SaO 2 did n ' t change apparently . ^^^ Moreover , lowering of FYN on PAP and PVR were superior to that of LT . ^^^ The experimental studies showed that LT and injection of FYN could completely inhibit the hypoxia caused increase of PAP and PVR in rats ; reduce the hypoxia caused pulmonary artery hypertension ( PAH ) and improve PVR of rats , as well as increase CO . ^^^ |