| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| The activated pp 60 ( c Src ) and Fyn co immunoprecipitated with caveolin 1 in BPMVEC membrane . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| Caveolin 1 is a substrate for nonreceptor tyrosine kinases including Src , Fyn , and Abl . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| The coupling of PrPc to Fyn is dependent on caveolin 1 . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| Fyn is required for oxidative and hyperosmotic stress induced tyrosine phosphorylation of caveolin 1 . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| PrP ( C ) associates in rafts with a variety of signalling molecules , including caveolin 1 and Fyn and Src tyrosine kinases . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| A requirement for caveolin 1 and associated kinase Fyn in integrin signaling and anchorage dependent cell growth . ^^^ Caveolin 1 functions as a membrane adaptor to link the integrin alpha subunit to the tyrosine kinase Fyn . ^^^ These findings reveal an unexpected function of caveolin 1 and Fyn in integrin signaling and anchorage dependent cell growth . . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| Similarly , fibronectin dependent fyn signaling through alpha 5 / beta 1 leading to mitogen activated protein ( MAP ) kinase activation requires the presence of caveolin 1 . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| This protein , pp 29 , was tightly bound to the caveolar coat protein caveolin 1 . pp 29 was among the most prominent phosphoproteins observed in cells overexpressing Fyn , suggesting that it may be a Fyn substrate . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| Finally , we have observed that after IGF 1 stimulation , IGF IR and Fyn colocalize in lipid raft caveolin 1 enriched microdomains . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| This interaction requires the phosphorylation of caveolin 1 on tyrosine 14 by members of the Src family of protein kinases , such as Src and Fyn , because it is completely abolished by expression of a catalytically inactive Src mutant or by site directed mutagenesis of tyrosine 14 of caveolin 1 . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| It has been demonstrated that PrP ( c ) is bound to cav 1 and , by recruiting Fyn kinase , can participate in signal transduction events connected to cell survival and differentiation . ^^^ |
|
| Interacting proteins: Q03135 and P06241 |
Pubmed |
SVM Score :0.0 |
| According to the known functions of their genes , the clusters were designated as proliferating cell ( CDC 42 , TOP2A , FGFR 3 , MYC , etc . ) , neoangiogenesis and blood cell ( LCK , VAV 1 , KDR , VEGF , MMP 9 , SYK , PTPRS , and FLT 4 ) , invasion 1 and invasion 2 ( ADAM 17 , TRPM 2 , DUSP 6 , VIM , CAV 1 , CAV 2 , JAK 1 , PTPNS 1 , FYN , and PDGFB ) , HER 2 , and PSA / PSM / HER3 . ^^^ |
|