Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.82214406 |
TCR induced WASp tyrosine phosphorylation was also disrupted in T cells lacking Fyn , a kinase shown here to bind , colocalize with , and phosphorylate WASp . 0.82214406^^^ |
|
Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
Under conditions of increased detergent stringency Sam 68 , Wiskott Aldrich Syndrome protein , and hnRNP K , but not Cbl and Fyn , were bound to the Itk SH 3 domain . ^^^ |
|
Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
Interaction between Wiskott Aldrich Syndrome protein ( WASP ) and the Fyn protein tyrosine kinase . ^^^ |
|
Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
WASp bound preferentially in vitro to SH 3 domains from c Src family kinases , and analysis of proteins expressed in insect cells using a baculovirus vector demonstrated a specific interaction between WASp and the Fyn protein tyrosine kinase . ^^^ Finally , in vivo experiments showed that WASp and Fyn physically associate in human haematopoietic cells . ^^^ Our data suggest that binding of Fyn to WASp may be a critical event in such signalling pathways in haematopoietic cells . . ^^^ |
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Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
Using affinity precipitation , WASP was found to bind to Src SH 3 containing proteins Fyn , Lck , PLC gamma , and Grb 2 , and mutated WASP , if expressed , was able to bind to Fyn glutathione S transferase ( GST ) fusion protein . ^^^ |
|
Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
The molecular adaptor adhesion and degranulation promoting adaptor protein ( ADAP ) , also known as Fyn binding protein ( FYB ) or Slp 76 associated protein of 130 kilodaltons ( SLAP 130 ) , interacts with a number of signaling intermediates including Slp 76 , the Src family tyrosine kinase Fyn , vasodilator stimulated phosphoprotein ( VASP ) , and the actin nucleating protein WASP . ^^^ |
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Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
Like other adapters , ADAP is a multifunctional protein and interacts with molecules such as Fyn , Slp 76 , Ena / VASP proteins , Vav 1 , WASP and the Arp2 / 3 complex . . ^^^ |
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Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
In addition , the reconstituted WASP interacted in vitro with proteins containing SH 3 domain such as Grb 2 , PLC gamma 1 , and Fyn , each of which are connected to signaling pathways linked to the actin cytoskeleton . ^^^ |
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Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P42768 and P06241 |
Pubmed |
SVM Score :0.0 |
NA |
|