| Interacting proteins: P06241 and P42574 |
Pubmed |
SVM Score :0.0 |
| Treatment of lymphocytes with Na [ Cr ( 5 ) O ( ehba ) ( 2 ) ] and K ( 2 ) Cr ( 2 ) O ( 7 ) leads to the activation of the Src family protein tyrosine kinases namely , p 56 ( lck ) , p 59 ( fyn ) , and p56 / 53 ( lyn ) , which then activates caspase 3 , both of which are under the partial influence of ROS . ^^^ |
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| Interacting proteins: P06241 and P42574 |
Pubmed |
SVM Score :0.0 |
| Caspase 3 cleavage of the Ste 20 related kinase SLK releases and activates an apoptosis inducing kinase domain and an actin disassembling region . ^^^ We have demonstrated that a novel Ste 20 related kinase , designated SLK , mediates apoptosis and actin stress fiber dissolution through distinct domains generated by caspase 3 cleavage . ^^^ SLK was cleaved by caspase 3 in vitro and in vivo during c Myc , tumor necrosis factor alpha , and UV induced apoptosis . ^^^ |
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| Interacting proteins: P06241 and P42574 |
Pubmed |
SVM Score :0.0 |
| Fyn and Lyn but not Lck , Src and Hck were processed in vitro by human recombinant caspase 3 and by cellular extracts prepared from Fas stimulated cells . ^^^ |
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| Interacting proteins: P06241 and P42574 |
Pubmed |
SVM Score :0.0 |
| Downregulating Sca 1 expression derepresses Fyn at the time of myoblast cell cycle withdrawal , and dominant negative and constitutively active Fyn mutants rescue and recapitulate the Sca 1 antisense phenotype , respectively . ^^^ This suggests a Fyn mediated mechanism for Sca 1 action . ^^^ |
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| Interacting proteins: P06241 and P42574 |
Pubmed |
SVM Score :0.0 |
| Interestingly , PP 2 , a specific Src like kinase inhibitor , blocked the tyrosine phosphorylation of Src , Fyn , and Lyn and IGF 1 stimulated Akt activation , yet had no significant effects on caspase 3 activation or progenitor survival . ^^^ |
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| Interacting proteins: P06241 and P42574 |
Pubmed |
SVM Score :0.0 |
| Furthermore , TSP 1 / REC showed decreased intracellular levels of active Fyn and JNK 2 without affecting caspase 3 activity . ^^^ |
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| Interacting proteins: P06241 and P42574 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06241 and P42574 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06241 and P42574 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06241 and P42574 |
Pubmed |
SVM Score :0.0 |
| NA |
|