| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| Two of these proteins represented the tyrosine kinase fyn and the mouse homologue of phospholipase C gamma 1 , whereas two genes encoded proteins similar to 5 crk and NCK . ^^^ |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| Thus , we examined the interactions of various SH 2 containing molecules like PLC gamma 1 , rasGAP , p 85 subunit of PI 3 kinase , Src , Fyn , Crk , Nck , Grb 2 and Shc with HEK 2 using in vitro binding assays , immunoprecipitations and yeast Two Hybrid assays . ^^^ |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| By screening a phage expression library using the monoclonal antibody ( mAb ) B 16 5 which recognizes Src homology 3 ( SH 3 ) domains of phospholipase C gamma and Nck , we have cloned a cDNA encoding the larger species of fyn mRNA . ^^^ |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| It binds in vivo to the adaptor proteins Nck and Grb 2 , to the cytoplasmic protein tyrosine kinase Fyn and to the small Rho like GTPase Cdc 42 , which is required for formation of filopodia in fibroblasts and macrophages . ^^^ |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| Insulin receptor phosphorylated IRS5 / DOK4 associates with RasGAP , Crk , Src , and Fyn , but not phosphatidylinositol 3 kinase p 85 , Grb 2 , SHP 2 , Nck , or phospholipase Cgamma Src homology 2 domains , and activates MAPK in cells . ^^^ |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| One group of SH 2 domains ( Src , Fyn , Lck , Fgr , Abl , Crk , and Nck ) preferred sequences with the general motif pTyr hydrophilic hydrophilic Ile / Pro while another group ( SH 2 domains of p 85 , phospholipase C gamma , and SHPTP 2 ) selected the general motif pTyr hydrophobic 10 hydrophobic . ^^^ |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| Using a GST fusion protein carrying the cytoplasmic tail of beta dystroglycan , we identified five SH 2 domain containing proteins that interact with beta dystroglycan in a phosphorylation dependent manner , including c Src , Fyn , Csk , NCK , and SHC . ^^^ |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06241 and P16333 |
Pubmed |
SVM Score :0.0 |
| NA |
|