| A major substrate of src type kinases , cortactin ( p80 / 85 ) , and the tyrosine kinase fyn copurified with N syndecan from hippocampus . ^^^ Moreover , association of both cortactin and fyn to N syndecan was rapidly increased after induction of LTP . ^^^ N syndecan may thus act as an important regulator in the activity dependent modulation of neuronal connectivity by transmitting signals between extracellular heparin binding factors and the fyn signaling pathway . . ^^^ |