| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| In Jurkat T cells , 2 bromopalmitate blocked localization of the endogenous palmitoylated proteins Fyn , Lck , and LAT to DRMs . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| Other downstream effectors of the TCR / CD3 transduction machinery , such as phosphatidylinositol 3 kinase p85alpha , p 59 ( fyn ) , linker for activation of T cells ( LAT ) , and phospholipase C gamma 1 , are not affected . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| Of note , CD 2 dependent Dok but not linker from activated T cells ( LAT ) tyrosine phosphorylation requires p 59 ( fyn ) . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| About 50 % of the T cells from young mice that formed conjugates with peptide pulsed APC were found to form complexes , at the site of binding to the APC , containing CD3epsilon , linker for activation of T cells ( LAT ) , and Zap 70 in a central area and c Cbl , p 95 ( vav ) , Grb 2 , PLC gamma , Fyn , and Lck distributed more uniformly across the interface area . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| As compared to peripheral blood ( PB ) T lymphocytes , SF T cells from some ( but not all ) of the patients analyzed expressed lower levels of TCRalphabeta , CD3epsilon , TCRzeta , p 56 ( lck ) and LAT , while p 59 ( fyn ) , phospholipase C gamma 1 and ZAP 70 expression was unaltered . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| While CD 2 induced p 62 ( dok ) tyrosine phosphorylation was independent of both the p36 / 38 membrane adapter protein linker of activated T cells ( LAT ) and the ZAP70 / Syk family of kinases , it was dependent upon the Src family of kinases including Lck and Fyn . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| Immobilized ophioluxin was used to isolate the glycoprotein 6 Fcgamma complex from resting platelets , which also contained Fyn , Lyn , Syk , LAT , and SLP 76 . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| We report here that Fc epsilon RI also uses a Fyn kinase dependent pathway that does not require Lyn kinase or the adapter LAT for its initiation , but is necessary for mast cell degranulation . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| Among these LAT , SLP 76 and Gab 2 are critically important as adapters that facilitate events initiated by IgE receptor dependent activation of Src family protein tyrosine kinases , Lyn and Fyn . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| Here we demonstrate that E2A is required for the complete arrest in both differentiation and proliferation observed in thymocytes with defects in proteins that mediate pre TCR signaling , including LAT , Lck and Fyn . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| We show here that cross linking of PrPc with specific antibodies leads to 1 ) PrPc capping in Jurkat and human peripheral blood T cells ; 2 ) to cocapping with the intracellular lipid raft proteins reggie 1 and reggie 2 ; 3 ) to signal transduction as seen by MAP kinase phosphorylation and an elevation of the intracellular Ca2+ concentration ; 4 ) to the recruitment of Thy 1 , TCR / CD3 , fyn , lck and LAT into the cap along with local tyrosine phosphorylation and F actin polymerization , and later , internalization of PrPc together with the reggies into limp 2 positive lysosomes . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| It contains not only the raft markers GM 1 and flotillin , but also some T cell receptor ( TCR ) signalling molecules , including Lck , Fyn and LAT . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| These defects resulted from impaired palmitoylation of LAT and were selective since the DRM localization and palmitoylation of Fyn were intact . ^^^ |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43561 and P06241 |
Pubmed |
SVM Score :0.0 |
| NA |
|