| In addition to Fyn , Src and Lck also interact with magicin . ^^^ Magicin phosphorylation is not observed in an Lck deficient line , J . ^^^ CaM1 . 6 , indicating that Lck is the major Src family kinase for phosphorylating magicin in Jurkat cells . ^^^ Employing site directed mutagenesis along with in vitro kinase assays , we found that Y 64 of magicin is phosphorylated by Lck creating a SH 2 Grb2 binding motif . ^^^ |