| Interacting proteins: Q14761 and P06239 |
Pubmed |
SVM Score :0.80998256 |
| These results demonstrate that CD 45 AP associates directly and selectively with Lck and ZAP 70 in response to T cell receptor mediated stimulation . 0.80998256^^^ |
|
| Interacting proteins: Q14761 and P06239 |
Pubmed |
SVM Score :0.70077131 |
| Interestingly , the ability of CD 45 AP to interact with Lck in the absence of other lymphoid specific molecules was proportional to the degree of catalytic activation of p 56 ( lck ) . 0.70077131^^^ |
|
| Interacting proteins: Q14761 and P06239 |
Pubmed |
SVM Score :0.0 |
| Interestingly , the interaction between CD 45 and Lck was significantly reduced in CD 45 AP null T cells , indicating that CD 45 AP directly or indirectly mediates the interaction of CD 45 with Lck . ^^^ |
|
| Interacting proteins: Q14761 and P06239 |
Pubmed |
SVM Score :0.0 |
| Biochemical analysis of the CD 45 p56 ( lck ) complex in Jurkat T cells lacking expression of lymphocyte phosphatase associated phosphoprotein . ^^^ In human and mouse lymphocytes the protein tyrosine phosphatase CD 45 , a key molecule involved in T cell activation , non covalently associates with the tyrosine kinase p 56 ( lck ) and lymphocyte phosphatase associated phosphoprotein ( LPAP ) , a 32 kDa phosphoprotein of unknown function . ^^^ Analysis of the CD 45 p56 ( lck ) molecular complex in this cell line revealed that loss of LPAP does not alter the expression or the enzymatic activity of CD 45 or p 56 ( lck ) . ^^^ In addition , the association between CD 45 and p 56 ( lck ) is not affected in LPAP deficient T cells . ^^^ These data suggest that LPAP does not regulate the enzymatic activity of CD 45 or p 56 ( lck ) and is not required for the association between these two proteins . ^^^ |
|
| Interacting proteins: Q14761 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14761 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14761 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14761 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|