| Interacting proteins: P40259 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40259 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40259 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40259 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P40259 and P06239 |
Pubmed |
SVM Score :0.0 |
| Consistent with the proposed role for src family tyrosine kinases in AgR signaling , we found that Lck could phosphorylate the cytoplasmic tails of the Ig alpha and Ig beta components of the B cell AgR in vitro . ^^^ Lck phosphorylated both of the tyrosines in the Ig beta AgR homology motif and one of the two tyrosines in the Ig alpha AgR homology motif . ^^^ |
|
| Interacting proteins: P40259 and P06239 |
Pubmed |
SVM Score :0.0 |
| Both Ig alpha and Ig beta were able to trigger Fyn , Lck , and ZAP directly without involvement of TCR components . ^^^ Cytoplasmic tyrosine residues in Ig beta were required for recruitment and activation of ZAP 70 , but these amino acids were not essential for the activation of Fyn and Lck . ^^^ |
|
| Interacting proteins: P40259 and P06239 |
Pubmed |
SVM Score :0.0 |
| We assessed the expression and methylation status of CD 19 , CD 20 , CD79B , SYK , PU . 1 , BOB . 1 / OBF . 1 , BCMA , and LCK , all of which are typically down regulated in cHL . ^^^ |
|