| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.70633148 |
| Previous studies have shown that Lck associates with , and becomes activated by , Kit after SCF stimulation of SCLC cells . 0.70633148^^^ |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.67333543 |
| Lck associates with and is activated by Kit in a small cell lung cancer cell line : inhibition of SCF mediated growth by the Src family kinase inhibitor PP 1 . 0.67333543^^^ |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| FGFs as single growth factors failed to support cultures of highly purified Lin ( ) Sca 1 ( + ) c Kit ( + ) ( LSK ) cells . ^^^ |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| A non radioactive Tyrosine Kinase Assay Kit was used to measure p56lck activity . ^^^ |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| We report here that the only progenitors in blood with efficient T lineage potential were lineage negative with high expression of stem cell antigen 1 and c Kit ( LSK cells ) . ^^^ |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| In the study reported here , unfractionated bone marrow ( BM ) cells or highly purified Lin ( ) Sca 1 ( + ) c kit ( + ) ( LSK ) cells were serially transplanted in lethally irradiated D 2 and B 6 mice . ^^^ |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| MATERIALS AND METHODS : We analyzed by flow cytometry the cell cycle status of lin ( low ) sca 1 ( + ) c kit ( + ) ( LSK ) stem cells isolated from the bone marrow of C57Bl / 6 mice sacrificed at 0 , 2 , 4 , 6 , 8 , 12 , 20 , 48 , 72 , and 96 hours after intraperitoneal injection of Ara C ( 100 mg / kg ) using 7 aminoactinomycin D ( 7 AAD ) for DNA staining . ^^^ |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| Nevertheless , the deletion of Lyl 1 results in a diminution in the frequency of immature progenitors ( Lin ( ) , CD 34 ( ) , sca 1 ( + ) , c kit ( + ) [ LSK ] , and LSK side population [ LSK SP ] ) and in S ( 12 ) colony forming unit ( CFU S ( 12 ) ) and long term culture initiating cell ( LTC IC ) content in embryonic day 14 fetal liver ( E 14 FL ) and adult bone marrow ( BM ) . ^^^ |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| The present study investigates whether highly purified mouse adult hematopoietic stem cells ( HSCs ) , characterized by lineage marker depletion and expression of the cell surface markers Sca 1 and c Kit ( Lin ( ) Sca 1 ( + ) c Kit ( + ) [ LSK ] ) , can be stimulated to adopt a neuronal fate . ^^^ |
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| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| In order to understand the mode of PI 3 kinase activation by the IL 2 receptor , we examined the association of PI 3 kinase to SH 2 and SH 3 domains of lck and fyn in IL 2 dependent kit 225 cells . ^^^ |
|
| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| The p56lck activity , determined by a non radioactive Tyrosine Kinase Assay Kit , was significantly higher in active SLE PBLs and discriminated this group of patients from inactive SLE patients ( p = 0 . 002 ) and healthy donors ( p = 0 . 009 ) . p56lck level decreased in SLE lymphocytes ( especially for inactive SLE lymphocytes , p = 0 . 005 ) when compared to healthy donors . ^^^ |
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| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| In vitro , TGF beta 2 , but not TGF beta 1 and TGF beta 3 , had a biphasic dose response on the proliferation of purified lin Sca 1 ( ++ ) kit ( + ) ( LSK ) cells , with a stimulatory effect at low concentrations , which was subject to mouse strain dependent variation . ^^^ |
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| Interacting proteins: P10721 and P06239 |
Pubmed |
SVM Score :0.0 |
| We present a mass spectrometric method using an isobaric covalent modification of peptides for relative quantification ( iTRAQ ) , which was employed to compare the proteomes of approximately 1 million long term reconstituting hematopoietic stem cells ( Lin ( ) Sca ( + ) Kit ( + ) ; LSK ( + ) ) and non long term reconstituting progenitor cells ( Lin ( ) Sca ( + ) Kit ( ) ; LSK ( ) ) , respectively . ^^^ |
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