| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| In addition , we identified several proteins that have not been correlated previously with pancreatic cancer including perlecan ( HSPG 2 ) , CD 9 antigen , fibronectin receptor ( integrin beta 1 ) , and a novel cytokine designated as predicted osteoblast protein ( FAM3C ) . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| The most intense and consistent degree of reactivity was seen using MAB to CD 9 , CD 13 , CD 29 , CD 31 , CD 44 , CD 46 , CD 51 , CD 54 and CD 55 , although reactivity was also observed using MAB belonging to CD 41 , CD 47 , CD 49 , CD 61 and CD 71 , in addition to a number of non clustered MAB . . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| Consistent with previous reports on tissue derived mast cells , those derived from foetal liver in vitro expressed HLA class 1 , CD 9 , CD 29 , CD 33 , CD 43 , CD 45 and Kit . ^^^ |
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| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| In line with previous observations , antibodies within CD 9 , CD 13 , CD 26 , CD 29 , CD 31 , CD 34 , CD 44 , CD 46 , CD 47 , CD 49 , CD 51 and CD 54 gave significant and consistent reactivity using non stimulated ( ' quiescent ' ) endothelium . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| Localization of the transmembrane 4 superfamily ( TM4SF ) member PETA 3 ( CD 151 ) in normal human tissues : comparison with CD 9 , CD 63 , and alpha5beta1 integrin . ^^^ It has recently been shown that several members of the tetraspan superfamily , including CD 9 and CD 63 , associate with each other and with beta 1 integrins . ^^^ In this study , we examined the distribution of a recently identified tetraspan , PETA 3 ( CD 151 ) , and of CD 9 , CD 63 , alpha5beta1 , and the integrin beta 1 chain in normal human tissues by the indirect immunoperoxidase and alkaline phosphatase anti alkaline phosphatase techniques . ^^^ The findings of this study show co localization of PETA 3 with CD 9 , CD 63 , alpha5beta1 , and beta 1 in particular tissues , demonstrating that tetraspan / integrin complexes may occur . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| We show that treatment of K 562 cells with 12 O tetradecanoylphorbol 13 acetate ( TPA ) which induces megakaryocytic differentiation , leads to a seven fold increase in CD 9 expression , which becomes associated with the integrin beta 1 , suggesting that it is functionally relevant . ^^^ |
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| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| CD 9 , but not other tetraspans , associates with the beta 1 integrin precursor . ^^^ We now show that CD 9 associates with the precursor of the beta 1 integrin ( pre beta 1 ) . ^^^ This association is detected as early as 15 min after metabolic labeling , and the use of Brefeldin A demonstrates that it does not require Golgi modifications of either CD 9 or integrin beta 1 . ^^^ The specificity of this interaction is demonstrated by the fact that other tetraspans , CD 63 , CD 81 , and CD 82 , do not associate with pre beta 1 , and CD 9 does not associate with immature human histocompatibility leukocyte antigen class 1 . ^^^ In order to localize the region of CD 9 responsible for the association with the beta 1 integrin , we have generated two reciprocal chimeric CD9 / CD82 molecules with the junction localized just after the third TM region . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| TNF alpha or IL 1beta did not change the expression of CD 9 , CD 13 , CD 16 , CD 23 , CD 29 , CD 31 , CD 32 , CD 35 , CD 45 , CD 61 , or CD 64 in BEAS 2B cells . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| Double staining with toluidine blue and immunofluorescence using monoclonal antibodies ( mAbs ) revealed expression of stem cell factor ( SCF ) receptor ( c kit / CD117 ) , CD 9 , CD 29 , CD 33 , CD 43 , CD 44 , CD 54 , and CD 63 on HRMCs . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| RESULTS : In both groups of patients ( RA and OA ) , SyMC were found to react with MAb to IgE , SCF receptor ( c kit , CD 117 ) , as well as CD antigens likewise expressed in lung MC ( CD 9 , CD 29 , CD 33 , CD 43 , CD 44 , CD 45 ) . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| Confirming our previous analyses on lung MC , foreskin MC reacted with MoAb against CD 9 , CD 29 , CD 33 , CD 43 , CD 44 , CD 45 , CD 46 , CD 51 , CD 54 , CD 55 , CD 58 , CD 59 , CD 61 , and CD 117 ( c kit ) . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| We studied the changes in expression of CD 9 and beta 1 integrins ( CD 29 , VLA ) in human vascular smooth muscle cells ( VSMCs ) under in vitro culture conditions mimicking proliferative vascular diseases . ^^^ In the contractile phenotype , the levels of CD 9 , CD 81 , another tetraspanin , and CD 29 are approximately 50 % of those found in the proliferative phenotype . ^^^ Coimmunoprecipitation experiments showed physical association between CD 9 and CD 29 . ^^^ Anti CD 29 MoAbs inhibited gel contraction , but anti CD 9 MoAbs counteracted this inhibitory effect of anti CD 29 MoAbs . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| CD 9 is expressed on the cell surface of human granulosa cells and associated with integrin alpha6beta1 . ^^^ Recently , CD 9 was shown to be associated with beta 1 related integrins . ^^^ In this study , we examined the expression of CD 9 in human ovary and the relationship between CD 9 and integrin alpha6beta1 in GC . ^^^ The proteins purified from GC by immunoaffinity chromatography using anti integrin alpha 6 monoclonal antibodies were shown by Western blotting to include CD 9 as well as integrin beta 1 . ^^^ These findings suggest that CD 9 is a differentiation related molecule of GC and TI and that it is associated with integrin alpha6beta1 on the cell surface of GC , suggesting that CD 9 is implicated in the function of human GC in cooperation with integrin alpha6beta1 . . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| Immunoprecipitation of T cell lysates with anti CD 9 mAb followed by immunoblotting with mAb against various T cell molecules showed the association of CD 9 with CD 3 , CD 4 , CD 5 , CD 2 , CD 29 and CD 44 . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| There was increased expression of adhesion receptors ( CD11c , CD 29 , CD 36 , CD 44 , CD49e , CD 54 ) , receptors involved in signal transduction and / or inflammation ( CD 13 , CD 45 , CD 53 ) , and other markers ( CD 9 , CD 52 , CD 71 , CD 98 , HLA Class 1 ) on macrophages from ILD patients compared to the non ILD group . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| MLSC was able to measure antigens CD 9 , CD 29 , CD 36 , CD 41 , CD42a , CD42b , and CD 61 on platelets and determine an average of 2 . 3 10 10 ( 5 ) + / 7 10 10 ( 4 ) platelets per microliter . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| Expressed proteins include CD 9 , CD 10 , CD 13 , CD 29 , CD 34 , CD 44 , CD 49 ( d ) , CD 49 ( e ) , CD 54 , CD 55 , CD 59 , CD 105 , CD 106 , CD 146 , and CD 166 . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| PMP stimulation of ECs increased CD 54 and CD 63 but not CD 9 , CD 29 , and CD 31 . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| It also contained signaling molecules such as Xyk ( Xenopus egg Src ) , Gq alpha , Ras , integrin beta 1 and CD 9 . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| Based on their immunophenotype , the cells are relatively homogeneous , with shared expression of integrin beta ( 1 ) , the hyaluronate receptor , and the tetraspan protein CD 9 , among other markers . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| By means of dissection / proteinase digestion techniques , high numbers of viable mononuclear cells were harvested from human placenta at term , and a mesenchymal cell population with characteristic expression of CD 9 , CD 29 , and CD 73 was obtained in culture . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| Interesting was the broad species overlapping reactivity of mAb directed against CD 9 ( 11 out of 17 species ) , CD11a ( 11 / 17 ) , CD 14 ( 11 / 17 ) , CD 18 ( 13 / 17 ) , CD 21 ( 7 / 17 ) , CD 29 ( 10 / 17 ) , CD 44 ( 13 / 17 ) , CD 45 ( 9 / 17 ) , CD 47 ( 10 / 17 ) , and CD49d ( 13 / 17 ) , CD 61 ( 6 / 17 ) , CD 86 ( 7 / 17 ) , CD 91 ( 5 / 17 ) , and CD172a ( 10 / 17 ) , indicating evolutionary highly conserved epitopes on these surface molecules . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| Blocking antibodies to integrin beta 1 , CD 44 , or CD 9 affected neither the MIA PaCa 2 binding to HUVEC nor the reduction of TEER . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| This study was undertaken to examine the tissue distribution of a broad spectrum of monoclonal antibodies ( mAbs ) containing tetraspan antigens ( CD 9 , CD 63 , CD 151 ) , endothelial cell antigens ( CD 31 , CD 36 , CD 105 , CD 106 , CD 146 ) , integrins ( CD49a f , CD 29 , CD 41 , CD 51 , CD 61 ) , CD 39 , CD 98 , CD 99 , CD 143 and , CD 147 supplied from fifth and sixth international workshops and conferences on human leukocyte differentiation antigens in a comparative manner in human OA and normal synovium . ^^^ |
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| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| Here , we have focused on ADAM proteins , tetraspanins CD 9 and CD 81 , and the integrin beta 1 subunit , which is co expressed in testis with integrin alpha 3 and integrin alpha 6 subunits , to understand how these molecules may stabilize spermatogenic cell attachment to Sertoli cell surfaces . ^^^ Like ADAM proteins , integrin beta 1 , alpha 3 , and alpha 6 subunits , and CD 9 and CD 81 transcripts are expressed in the fetal testis and throughout testicular maturation , as well as , in Sertoli spermatogenic cell co cultures . ^^^ During spermatogenic cell apoptosis , integrin beta 1 , alpha 3 , and alpha 6 subunits , and tetraspanins CD 9 and C 81 become displaced away from the developing apoptotic bodies . ^^^ |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P21926 and P05556 |
Pubmed |
SVM Score :0.0 |
| NA |
|