| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| The following activities have been detected : eIF 2 , eIF3 / 4F , eIF4A , eIF4B , eIF4C , eIF4D , and eIF 5 . ^^^ |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| Several initiation factors ( eIF 2 , eIF 3 , eIF 4A , eIF 4B , eIF 4C , eIF 4E and eIF 5 ) and elongation factor 1 were found to have no such discriminatory effect . ^^^ |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| Detailed information about the binding sites for eIF 1A , eIF 2 , eIF 3 , and Met tRNA ( 1 ) on the 40S ribosomal subunit was derived from the AFM images . ^^^ |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| The resulting complex requires eIF 1 , eIF1A , eIF4A , eIF4B and eIF4F to bind to a messenger RNA and to scan to the initiation codon . eIF 5 stimulates hydrolysis of eIF 2 bound GTP and eIF 2 is released from the 48S complex formed at the initiation codon before it is joined by a 60S subunit to form an active 80S ribosome . ^^^ |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| Domains of eIF1A that mediate binding to eIF 2 , eIF 3 and eIF5B and promote ternary complex recruitment in vivo . ^^^ Translation initiation factor 1A ( eIF1A ) is predicted to bind in the decoding site of the 40S ribosome and has been implicated in recruitment of the eIF 2 GTP Met tRNA 1 Met ternary complex ( TC ) and ribosomal scanning . ^^^ The unstructured N terminus of eIF1A interacts with eIF 2 and eIF 3 and is required at low temperatures for a step following TC recruitment . ^^^ |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| Translation initiation factor 1A stimulates 40S binding of the eukaryotic initiation factor 2 ( eIF 2 ) / GTP / Met tRNA ( iMet ) ternary complex ( TC ) and promotes scanning in vitro . eIF1A contains an OB fold present in bacterial IF 1 plus N and C terminal extensions . ^^^ |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| Recruitment of the eukaryotic translation initiation factor 2 ( eIF 2 ) GTP Met tRNAiMet ternary complex to the 40S ribosome is stimulated by multiple initiation factors in vitro , including eIF 3 , eIF 1 , eIF 5 , and eIF1A . ^^^ |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| Our data indicate that stimulation of GTP hydrolysis by eIF5B requires the completion of early steps in translation initiation , including the eIF 1 and eIF1A dependent delivery of initiator methionyl tRNA to the 40 S ribosomal subunit and subsequent GTP hydrolysis by eIF 2 . ^^^ |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P47813 and P05198 |
Pubmed |
SVM Score :0.0 |
| NA |
|