| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| These different effects are mediated through the IL4R complex including the IL2R gamma chain ( gamma c ) and a specific p130 / 140 binding unit referred below as human Interleukin 4 Receptor ( IL 4 R ) . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| An antagonistic mutant of interleukin 4 fails to recruit gamma c into the receptor complex . ^^^ The receptor for interleukin 4 ( IL 4 ) appears to be a heterodimer of the IL 4 binding protein IL 4R alpha and the gamma c chain . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| The mode of binding of interleukin 4 ( IL 4 ) to its two known receptors , specific receptor IL 4R and a shared receptor gamma c , was investigated using gel filtration and gel electrophoresis . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| Unlike anti CD 40 mAb or CD40L , IB 4 mAb neither induced a proliferation of GC B cells nor increased their proliferative response to anti CD 40 , CD40L or recombinant interleukin 4 , used alone or in combination . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| X SCID B cell responses to interleukin 4 and interleukin 13 are mediated by a receptor complex that includes the interleukin 4 receptor alpha chain ( p 140 ) but not the gamma c chain . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| Interleukin 4 signal transduction ( and activation of STAT 6 ) is known to be mediated via its binding to a p 140 receptor chain and the common gamma chain ( gamma c ) . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| We asked whether a combination of Bcl 2 expression and the provision of a culture environment that mimicked that of the GC [ CD 40 ligation and interleukin 4 ( IL 4 ) ] could increase the ability of B lymphoma cells to resist drug induced apoptosis . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| Interleukin 2 , interleukin 4 , and interleukin 7 all utilize the common gamma ( gamma c ) receptor component at the cell surface of lymphocytes and the Jak 3 kinase molecule to transduce signals inside the cell . ^^^ Interleukin 2 and interleukin 4 function by influencing mature lymphocyte populations during immune responses , whereas interleukin 7 plays a singularly dominant role , in terms of the ligands that bind to the gamma c receptor , for the production and expansion of lymphocytes . . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| Functional interleukin 4 receptor and interleukin 2 receptor common gamma chain on human non small cell lung cancers : novel targets for immune therapy . ^^^ Immunoprecipitation and blotting of the LUst cell line with specific secondary antibodies demonstrated that the 140 kd phosphoprotein was the interleukin 4 receptor , the 130 kd phosphoprotein was Janus kinase 1 , the 116 kd phosphoprotein was Janus kinase 3 , and the 65 kd phosphoprotein was the interleukin 2 receptor gamma chain . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| The feasibility of this TIR1 / 2 based method was examined by expression of IL 4 and the EC domains of the interleukin 4 receptor alpha ( IL 4Ralpha ) and the cytokine receptor common gamma chain ( gammaC ) as hybrid receptors with tmTIR 1 and tmTIR 2 . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| In order to elucidate the heterogeneity of Mphi 2 population systematically , we analysed a number of genes involved in extracellular matrix ( ECM ) remodelling , inflammation and phagocytosis in Mphi 2 populations generated with interleukin 4 ( IL 4 ) or GC . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| In this research , we studied the expression and function of CCR 3 induced by interleukin 2 ( IL 2 ) and interleukin 4 ( IL 4 ) on human germinal centre ( GC ) B cells . ^^^ |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P05112 and P31785 |
Pubmed |
SVM Score :0.0 |
| NA |
|