| Interacting proteins: Q92598 and P04792 |
Pubmed |
SVM Score :0.0 |
| Assignment of the mouse Hsp 25 and Hsp 105 genes to the distal region of chromosome 5 by linkage analysis . ^^^ |
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| Interacting proteins: Q92598 and P04792 |
Pubmed |
SVM Score :0.0 |
| To study a role of PrPC in the regulation of expression of heat shock proteins ( HSPs ) , a group of molecular chaperones , heat induced expression of major HSPs ( HSP 105 , HSP90alpha , HSP 72 , HSC 70 , HSP 60 , and HSP 25 ) was investigated in cultured skin fibroblasts isolated from the mice homogeneous for a disrupted PrP gene ( PrP / mice ) by Western blot analysis and immunocytochemistry . ^^^ In both SFK and SFH cells , HSP 105 , HSP 72 , and HSP 25 were expressed at low levels under unstressed conditions but they were induced markedly following exposure to heat stress ( 43 degreesC / 20 min ) at 3 72 h postrecovery . ^^^ The pattern of expression , induction , and subcellular location of HSP 105 , HSP 72 , HSC 70 , HSP 60 , and HSP 25 was not significantly different between SFK and SFH cells under unstressed and heat stressed conditions . ^^^ Furthermore , the levels of constitutive expression of HSP 105 , HSC 70 , HSP 60 , and HSP 25 were similar between the brain tissues isolated from the PrP / and PrP+ / + mice . ^^^ |
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| Interacting proteins: Q92598 and P04792 |
Pubmed |
SVM Score :0.0 |
| Total RNA was extracted from the heart kidneys and adrenals , and the mRNA levels of hsp 27 , hsp 70 , hsp 84 , hsp 86 and hsp 105 were measured . ^^^ |
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| Interacting proteins: Q92598 and P04792 |
Pubmed |
SVM Score :0.0 |
| The majority of these genes code for heat shock proteins ( hsp 70 , hsp 27 , hsp 40 , hsp 105 , GRP 78 , etc . ) . ^^^ |
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| Interacting proteins: Q92598 and P04792 |
Pubmed |
SVM Score :0.0 |
| Also , a number of genes that are upregulated by c Myc in cells expressing wild type conformation p 53 encode chaperones related to cell death protection as HSP 105 , HSP 90 and HSP 27 . ^^^ |
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| Interacting proteins: Q92598 and P04792 |
Pubmed |
SVM Score :0.0 |
| Specifically , cytosolic HSP 25 , HSP 40 , HSP 70 , HSP 105 and microsomal HSP 32 ( HO 1 ) were strongly upregulated within the first few hours of TFEC treatment , while little change was observed among other HSPs that are predominantly localized in the mitochondria and endoplasmic reticulum ( ER ) . ^^^ |
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