| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| Kinases increasing phosphorylation of the small heat shock protein ( HSP 27 ) and epidermal growth factor receptor have been identified and shown to be activated independent of protein kinase A or C . ^^^ |
|
| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| Thus , it was concluded that ER positive breast carcinomas , relatively small in size , preferentially expressed HSP 27 , HSP 70 and pS 2 and that ER negative tumors , relatively large in size , were predisposed to express p 53 , EGFR and c erbB 2 . . ^^^ |
|
| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| Several of the newer biologic markers of breast cancer may provide very specific treatment information . erbB 2 may predict for improved response to doxorubicin , rather than CMF . hsp 27 may predict for failure of doxorubicin . pS 2 or EGFR may provide supplemental information predicting response to hormonal therapy . ^^^ |
|
| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| Estrogen receptor ( ER ) , progesterone receptor , epidermal growth factor receptor , erbB 2 , and HSP 27 were measured by immunohistochemistry in paraffin fixed material obtained from the primary tumors at initial surgery . ^^^ |
|
| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| Many genes have been selected as targets for antisense therapy , including HER 2 / neu , PKA , TGF alpha , EGFR , TGF beta , IGFIR , P 12 , MDM 2 , BRCA , Bcl 2 , ER , VEGF , MDR , ferritin , transferrin receptor , IRE , C fos , HSP 27 , C myc , C raf and metallothionein genes . ^^^ |
|
| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| Thus EGFR independent p 38 MAPK and EGFR dependent ERK1 / 2 activation by TGHQ lead to the activation of two downstream signaling factors , i . e . , histone H 3 and Hsp 27 phosphorylation , which have in common the potential ability to remodel chromatin . . ^^^ |
|
| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04792 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|