Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.7383493
Remarkably , in NGF treated cells , it was only in CLM that activated TrkA was coimmunoprecipitated with phosphorylated Shc and PLCgamma . 0.7383493^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.67490934
Nerve growth factor induced stimulation of Ras requires Trk interaction with Shc but does not involve phosphoinositide 3 OH kinase . 0.67490934^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.65796634
In Shc signaling , NGF , but not BDNF , displayed interactions between Trk and Shc in a phenylarsine oxide ( PAO ; an inhibitor of tyrosine phosphatase ) dependent manner in TrkB expressing PC 12 cells . 0.65796634^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Mutational analysis suggests that SHC binding is essential for scattering and increased cell motility induced by trkA . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
These findings suggest that the EGF and NGF ( TrkA ) receptor can utilize Shc in different ways to promote their activity . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
TrkA mutated within its SHC binding site ( Y490F ) delays c Myc induced apoptosis without activating endogenous Akt / PKB . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
The signaling adapter FRS 2 competes with Shc for binding to the nerve growth factor receptor TrkA . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Conversely a dominant negative mutant of Shc inhibited TrkA but not p 75 activation of NF kappaB . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Phosphopeptide assays developed to compare PTB domain specificities show that the Shc PTB domain binds with highest affinity to psi XN beta 1 beta 2 pY motifs derived from middle T ( mT ) , TrkA , ErbB 4 , or epidermal growth factor receptors ( psi = hydrophobic , beta = beta turn forming ) ; the IRS 1 PTB domain does not bind with this motif . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Mutational analysis of the nerve growth factor ( NGF ) receptor ( TrkA ) suggested that the binding of Shc to the activated receptor is required for NGF induced neuronal differentiation of PC 12 cells . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Mutation of the Trk A residue Tyr 490 to phenylalanine prevents the association with Shc , while similar mutations at Tyr 751 or Tyr 785 are reported to prevent interaction of Trk A with the p 85 subunit of inositol phospholipid 3 kinase and phospholipase C gamma 1 , respectively . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Nerve growth factor induces a multimeric TrkA receptor complex in neuronal cells that includes Crk , SHC and PLC gamma 1 but excludes P130CAS . ^^^ Using receptor activated immunoprecipitation followed by analysis of the immune complexes by SDS PAGE and immunoblotting , we show that NGF induces the association of TrkA with c Crk 2 in a multimeric complex that also includes SHC and PLC gamma 1 . ^^^ While the tyrosine phosphorylation of TrkA , SHC and PLC gamma 1 increased with time in the presence of NGF and was inhibited by the tyrosine kinase inhibitor K252a , the state of tyrosine phosphorylation of c Crk 2 did not appear to change with NGF treatment . ^^^ Immunodepletion studies demonstrated that the interaction of c Crk 2 with TrkA not only occurs indirectly through the SHC proteins , but may also involve another mode of binding . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Both TrkC and TrkA mediate qualitatively similar increases in the tyrosine phosphorylation of phospholipase C ( PLC ) gamma 1 , Shc , SNT , and MAPK and the transcription of the c fos , c jun , NGFI A , and NGFI B immediate early genes . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Signal proteins such as phosphatidylinositol 3 kinase , phospholipase C gamma 1 , Shc , and mitogen activated protein kinase seem to be involved in both TrkA and TrkB mediated signaling pathways . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Herein , we demonstrate that TrkAKi receptors show a decrease in the absolute amount of kinase activity relative to wild type TrkA , yet retain normal patterns of receptor tyrosine phosphorylation , as determined by phosphopeptide mapping studies , unlike TrkC ( Ki 14 ) . nnr 5 cell clones expressing TrkAKi receptors show a decrease in nerve growth factor ( NGF ) mediated SHC tyrosine phosphorylation and a loss of high affinity TrkA SHC interaction comparable to those expressing TrkC ( Ki 14 ) . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
To the tyrosine phosphorylated sites of TrkA several proteins , such as phospholipase C gamma 1 , the adaptor protein SHC , the phosphotyrosine phosphatase SH PTP 2 ( SYP ) associate via their SH 2 phosphotase SH PTP 2 domain . ^^^ The association of SHC to TrkA is shown by co immunoprecipitation . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
In addition , using point mutations at specific TrkA autophosphorylation sites , we determined that mobility is controlled by multiple phosphorylation sites , but the SHC binding site at Y 490 may be particularly important for ligand induced immobilization of TrkA . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
NGF induced tyrosine phosphorylation of phospholipase Cgamma , TrkA , and Shc was unaltered in the Shb overexpressing cells , whereas that of Shb was greatly enhanced in these cells compared with control PC 12 neo cells . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Collectively , these data suggest that the TrkAS 3 deletion either directly affects a novel Ras independent TrkA binding protein or that the decrease in TrkAS 3 SHC association affects a Ras independent SHC binding protein essential for cell cycle arrest and / or neurite outgrowth . . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
We found that the action of the TrkA receptor on neuronal differentiation depends on specific motifs in the extracellular domain and on tyrosine 490 ( Y 490 ) , the site for SHC protein binding . ^^^ In contrast with previous observations in a PC 12 background , a mutation in the SHC Y 490 binding site in TrkA resulted in a loss of NGF dependent process formation . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
NGF . mAb induced activation of TrkA , Shc , and MAPK is transient compared with NGF induced activation ; yet NGF and NGF . mAb afford identical trophic responses . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Binding of the Shc PTB domain to tyrosine phosphorylated peptides from TrkA , epidermal growth factor , ErbB 3 , and insulin receptors is achieved via an overall entropy driven reaction . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Overexpression of either wild type or mutant SH 2 Bbeta ( R555E ) did not alter tyrosyl phosphorylation of TrkA , Shc , or phospholipase Cgamma in response to NGF or NGF induced activation of ERK1 / 2 , suggesting that SH 2 Bbeta may initiate a previously unknown pathway ( s ) that is essential for NGF induced neurite outgrowth . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Unglycosylated TrkA core protein is phosphorylated even in the absence of ligand stimulation and displays constitutive kinase activity as well as constitutive interaction with the signaling molecules Shc and PLC gamma . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
The PTB domains of Shc and IRS 1 both recognize autophosphorylation sites in RTKs with the consensus sequence NPXpY , but show distinct abilities to bind stably to RTKs such as the TrkA nerve growth factor receptor and the insulin receptor . ^^^ A triple substitution of the 5 , 8 and 9 residues relative to Tyr 960 of the IR to the corresponding amino acids found in the Shc PTB domain binding site of TrkA results in even stronger binding of the IR to Shc in vivo . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Complex formation with TrkA is dependent on phosphorylation of Y 490 , a canonical PTB domain binding site that also functions as a binding site for Shc ( NPXpY ) . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Herein , we demonstrate that acidic substitution of the activation loop tyrosines is sufficient to induce allosteric changes required for constitutive TrkA kinase activity as well as phosphorylation of TrkA signaling proteins such as Shc , PLCgamma 1 , FRS 2 and erk1 / 2 . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
The interaction with trkA is not affected by mutations at either Tyr 499 or Tyr 794 , the two major phosphotyrosine residues essential to the activation and receptor binding of Shc , FRS 2 / SNT , and phospholipase Cgamma 1 , and it is highly specific in vitro for trkA , with little or no binding observed with trkB and / or trkC . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Grb 2 binding to TrkA is independent of Shc , FRS 2 , phospholipase Cgamma 1 , rAPS , and SH2B and is observed in in vitro binding assays , yeast two hybrid assays , and in co immunoprecipitation assays . ^^^ By using acidic amino acid substitutions of the activation loop tyrosines on TrkA , we can stimulate constitutive kinase activity and TrkA Shc interactions but , importantly , abolish TrkA / Grb2 binding . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Thus , the activation of FRS 2 and Shc ( leading to MAPK activation ) is weaker in the DDR1 / TrkA chimeras than in TrkA alone , and the PLCgamma contribution becomes essential for full response . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Although the level of basal trkA receptor tyrosine phosphorylation was higher in the mutant than in the wild type , NGF stimulation of WT 11 and V432E transfectants resulted in a rapid increase in receptor tyrosine phosphorylation and of its intracellular adaptor protein SHC . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
These data together with the cofractionation of Shc , Ras , caveolin , and TrkA in the caveolae fraction supported a role for these plasma membrane microdomains in NGF signaling . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
The results indicate that these Shc family members possess both unique and overlapping functions in regulating neural development and suggest physiological roles for ShcB / ShcC in TrkA signaling . . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Mutation of TrkA at key autophosphorylation sites indicates an essential role for the phospholipase C gamma ( PLC gamma ) binding site , but not the Shc binding site , for NGF triggered induction of PN 1 . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
We show that p75NTR dependent Akt phosphorylation was independent of TrkA signaling , required active phosphatidylinositol 3 kinase , and was associated with increased tyrosine phosphorylation of p 85 and Shc and with reduced cytosolic tyrosine phosphatase activity . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Activation of the Shc / mitogen activated protein kinase pathway mediates the induction of MMP 9 in response to NGF , as this response is abrogated in cells expressing a mutant TrkA receptor that does not bind Shc and by pretreatment of cells with the MEK 1 inhibitor , U 0126 . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Cumulatively , our findings support a model in which Cys 436 of the trkA is responsible for the rapid transfer of the transmembrane occupancy signal to the SHC adaptor protein for activation of the Ras Erk pathway and DNA synthesis . . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
To explore the potential role ( s ) of Shc related adapters in NT signaling in the retina , we compared the developmental changes of the mRNA expression of TrkA B , and C in the rat retina , on one hand and , on the other hand , studied which members of the Shc family were activated after brain derived neurotrophic factor ( BDNF ) application in axotomized rat retinas . ^^^ Early in development , both TrkA and ShcA were highly expressed , whereas , in late development to adulthood , TrkB / C and ShcB / C were highly expressed . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Mapping analysis indicates that p 62 does not compete with Shc for binding to TrkA , and p 62 association was confined to the juxtamembrane region of TrkA , amino acids 472 493 . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
We also show that Dok 1 does not recognize peptide sequences from TrkA and IL 4 , which are recognized by Shc and IRS 1 , respectively . . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
The present analysis of early NGF signaling shows that the upstream activation of TrkA , as well as the recruitment of the adaptor protein Shc , are dramatically attenuated upon loss of cell adhesion , while the downstream activation of ERK1 / 2 is unaffected . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
The p 75 neurotrophin receptor enhances TrkA signalling by binding to Shc and augmenting its phosphorylation . ^^^ Using antisense techniques to down regulate p 75 ( NTR ) and TrkA , we found that p 75 ( NTR ) specifically enhanced phosphorylation of the 46 and 52 kDa isoforms of Shc during nerve growth factor induced TrkA activation . p 75 ( NTR ) did not enhance tyrosine phosphorylation of other TrkA substrates . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
This interaction and phosphorylation of RasGrf 1 is dependent on the HIKE domain of TrkA ( a region shown to interact with pleckstrin homology domains ) but not on any of the phosphotyrosine residues that act as docking sites for intracellular signaling molecules such as Shc and FRS 2 . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Consistent with the suppression , NAC inhibited NGF induced activation of TrkA , formation of receptor complexes comprising TrkA , Shc , Grb 2 , and Sos , and activation of phospholipase Cgamma and phosphatidylinositol 3 kinase . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
The Shc amino terminal domain also bound to the autophosphorylated nerve growth factor receptor ( Trk ) , but bound significantly less well to a mutant receptor in which tyrosine Y 490 in the receptor ' s Shc binding site had been substituted by phenylalanine . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
To transmit NGF signals , NGF activated Trk rapidly associates with the cytoplasmic proteins , SHC , PI 3 kinase , and PLC gamma 1 . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Maximal inhibition of VGF mRNA induction was achieved using K 252a , an inhibitor of the NGF receptor Trk tyrosine kinase , and by mutating both Y 490 ( SHC association site ) and Y 785 ( PLC gamma 1 association site ) of Trk . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
While Shc is also found bound to the activated NGF receptor , Trk , no complexes were detectable that contained both Trk and Grb 2 or Sos . ^^^ At low concentrations , another tyrosine phosphopeptide , TRK Y490P , which binds to the SH 2 domain of Shc , blocks growth factor induced formation of complexes between Shc and the EGF receptor or Trk , but fails to block activation of nucleotide exchange on Ras . ^^^ Higher concentrations of TRK Y490P inhibit tyrosine phosphorylation of Shc and the formation of Shc complexes with Grb 2 : this results in strong inhibition of Ras activation by NGF and partial inhibition of Ras activation by EGF . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
By comparison with recently reported SHC binding sites on Middle T antigen and Trk we have identified a SHC binding motif , NPXY . . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Trk receptors use redundant signal transduction pathways involving SHC and PLC gamma 1 to mediate NGF responses . ^^^ In response to NGF , the Trk receptor tyrosine kinase forms a complex with SHC , a protein that couples receptor tyrosine kinases to p21ras . ^^^ Complex formation between Trk and SHC , SHC tyrosine phosphorylation , and association of SHC with Grb 2 were mediated by autophosphorylation at Y 490 in Trk [ sequence : see text ] . ^^^ To determine the role of SHC and other Trk substrates in NGF signaling , Trk receptors with mutations in Y 490 and Y 785 ( the PLC gamma 1 association site ) were introduced into PC12nnr5 cells . ^^^ We postulate that Trk receptors can activate Erk 1 by either SHC or PLC gamma 1 dependent signaling pathways . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Neuronal differentiation signals are controlled by nerve growth factor receptor / Trk binding sites for SHC and PLC gamma . ^^^ In the central and peripheral nervous system and the phaeochromocytoma cell model PC 12 , NGF exerts its effects through the activation of the signalling capacity of Trk , a receptor tyrosine kinase ( RTK ) which upon interaction with NGF becomes phosphorylated on tyrosines and thereby acquires the potential to interact with signal transducing proteins such as phospholipase C gamma ( PLC gamma ) , phosphatidylinositol 3 ' kinase ( PI3 ' K ) and SHC . ^^^ Mutagenesis of the specific binding sites for these src homology 2 ( SH 2 ) domain containing substrates within the Trk cytoplasmic domain suggests a non essential function of PI3 ' K and reveals a major role for the signal controlled by the SHC binding site at tyrosine 490 and a co operative function of the PLC gamma mediated pathway for neuronal differentiation of PC 12 cells . . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
The oncogenic versions of the Ret and Trk tyrosine kinases bind Shc and Grb 2 adaptor proteins . ^^^ We have shown that the SH 2 domain of the adaptor protein Shc coimmunoprecipitates with all the Ret and Trk oncoproteins as well as with NGF activated proto Trk receptor . ^^^ Tyrosine phosphorylation of Trk proteins both normal and oncogenic is necessary for their binding to Shc . ^^^ In addition , in cells containing either Ret or Trk oncoproteins , Shc proteins are constitutively phosphorylated on tyrosine and bound to Grb 2 . ^^^ Finally , when proto Trk product is stimulated by NGF , Shc phosphorylation and association with Grb 2 are induced . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Identification of Trk binding sites for SHC and phosphatidylinositol 3 ' kinase and formation of a multimeric signaling complex . ^^^ In vitro association of SHC and the p 85 subunit of phosphatidylinositol 3 ' kinase with the Trk tyrosine kinase was prevented only by phosphorylated Y 490 and Y 751 containing peptides , respectively . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Tyrosine phosphorylated peptides derived from Trk ( pY 490 ) , polyoma virus middle T antigen ( pY 250 ) , ErbB 3 ( pY 1309 ) , and epidermal growth factor receptor ( pY 1086 , pY 1148 , and pY 1114 ) that contain NPXpY sequences bind preferentially to the PTB domain of Shc with Kd values of 0 . 02 5 . 3 microM . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Finally , our data define the minimal SHC PTB domain binding motif as NXX ( pY ) , not NPX ( pY ) as suggested by other authors , and suggest a high affinity motif , hydrophobic residue ( D / E ) N 10 10 pY ( W / F ) , found in the Trk and ErbB receptor tyrosine kinase families . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
N Shc : a neural specific adapter molecule that mediates signaling from neurotrophin / Trk to Ras / MAPK pathway . ^^^ In neuronal cells , such as PC 12 , Shc has been shown to be involved in Ras dependent MAP kinase activation following Trk receptor stimulation with NGF . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
BDNF and NT 3 resulted in not only the respective autophosphorylation of the Trk receptors , TrkB or TrkC , but also tyrosine phosphorylation of SHC , a protein involved in controlling p21ras activity , and phosphatidylinositol 3 ' ( PI 3 ' ) kinase . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Intracellular application of a phosphopeptide , Trk 490 , which prevents the binding of the adaptor protein shc to the activated NGF receptor , so blocking p 21 ras activation , reduced 1 ( max ) . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
The suppression of the increase in ROS by NGF was restored in nnr 5 cells stably expressing p 140 ( trk ) ( nnr 5 trk ) , but NGF failed to prevent the increase in ROS in nnr cells expressing mutant p 140 ( trk ) receptors that lack binding sites for Shc and phospholipase Cgamma . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
This system utilizes a Trk receptor mutant ( Trk ( def ) ) lacking sequences Y 490 , Y 785 and KFG important for the activation of the major Trk targets ; SHC , PLC gammal , Ras , PI 3 kinase and SNT . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
We analyzed the elements of the pathway that lead to this activation , and we observed that calmodulin antagonists completely block the initial Raf 1 activation without affecting the function of upstream elements , such as Ras , Grb 2 , Shc , and Trk . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Our results demonstrate that the signal transduction pathways through TRK A and TRK B in MP N TS cells are functional and similar , and the main downstream signaling pathways from the three neurotrophins are mitogen activated protein kinase ( MAPK ) cascades through Shc , activated Ras , ERK 1 and ERK 2 , and the transduction pathway through PLC gamma 1 . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Because activation of trk receptors involves phosphorylation of specific tyrosine residues ( Segal et al . , 1996 ) , the availability of antibodies that selectively recognize the phosphorylated form of trk receptors at the Shc site permits an immunohistochemical assessment of trk receptor activation . ^^^ In contrast , the epileptogenesis associated increase of p trk immunoreactivity was reduced in trkB ( shc ) mutant mice . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Interaction studies using different TRK T 3 mutants indicate that FRS 3 is recruited by the same tyrosine residue interacting with Shc and FRS 2 . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Because the Shc family proteins ( ShcA , ShcB , and ShcC ) are adaptors for various receptors , including Trk receptors , and are regulators of neuronal cell development , we speculated that they may play a role in neuroblastoma . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
These factors all regulate the docking proteins ( e . g . , IRS and Shc ) that link the activated Trk receptor to downstream effectors . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Overexpression of SAP with Trk attenuated tyrosine phosphorylation of the receptors and reduced the binding of SH2B and Shc to TrkB . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
Activation of Trk receptors leads to increased phosphorylation of Shc ( Src homology and collagen homology ) , phospholipase C gamma and novel adaptor molecules , such as the ARMS ( ankyrin rich membrane spanning ) / Kidins220 protein . ^^^
Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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Interacting proteins: P04629 and P29353	Pubmed	SVM Score :0.0
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