| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.8569613 |
| The interaction of c Abl with TrkA was also observed in differentiated pheochromocytoma PC 12 cells . 0.8569613^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| We detected transcripts for 2 cytoplasmic ( ABL and FES ) and 6 receptor ( ECK , ERB B 2 , FGF R 4 , IGFI R , KDR and TIE ) kinases but not for receptors RET or TRK A . ^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| Direct interaction of nerve growth factor receptor , TrkA , with non receptor tyrosine kinase , c Abl , through the activation loop . ^^^ We isolated c Abl as a TrkA interacting protein , in addition to known proteins such as phospholipase Cgamma and SH 2 B . ^^^ Furthermore , we show here that c Abl binds to phosphotyrosine residue ( s ) in the kinase activation loop of TrkA . . ^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| This study demonstrates that p 53 appears to associate with trk A via c abl . ^^^ Endogenous c abl was detected when the trk A and p 53 complex was immunoprecipitated from lysates of NGF stimulated NIH3T3 cells expressing trk A or NIH3T3 cells expressing trk A and a temperature sensitive p 53 ( val 135 ) . ^^^ Endogenous c abl and trk A association was observed in NGF stimulated p 53 negative fibroblasts transfected with trk A alone ; suggesting that c abl can independently bind to trk A in the absence of p 53 . ^^^ Interestingly , association between endogenous p 53 and trk A was not detected in NGF stimulated abl negative fibroblasts transfected with trk A or when these cells were exposed to gamma radiation . ^^^ This result suggests that p 53 preferentially binds to trk A in the presence of c abl and that p 53 and trk A do not appear to associate directly even if p 53 is activated and its levels increased by gamma radiation . ^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| A detailed analysis of the NIH 3T3 transformants generated from REC : myc : gamma 33 and gamma 41 DNA failed to detect Ha ras , Ki ras , raf , neu , trk , abl , fms , or src oncogenes of rat origin . ( ABSTRACT TRUNCATED AT 400 WORDS ) . ^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| Gene expression analysis showed measurable levels of mRNA for c Ki ras , erb B , erb B 2 , hck , src , lyn , vav , trk , raf 1 , l myc , c jun , c yes , c myc , c abl , and p 53 . ^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| Retroviral expression vectors carrying the tyrosine kinase oncogenes abl , fms , src , and trk abrogate the requirements of murine myeloid FDC P 1 cells for interleukin 3 ( IL 3 ) . ^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| Southern blot analysis of 3T3 or Rat 2 transfectants carrying oncogenes from radiation transformed C3H / 10T1 / 2 or hamster cells indicates that the oncogenes responsible for the transformation of 3T3 cells are not the Ki ras , Ha ras , or N ras genes , nor are they neu , trk , raf , abl , or fms , although quick blot analysis using 11 oncogene probes detected increased transcripts of c abl and c fms in the 3T3 transformants containing oncogenic sequences from the 10 ray transformed C3H / 10T1 / 2 cells . ^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| Class 1 revertants were also resistant to retransformation by 5 gag fos fox , 5 Ha ras , 5 abl , and 5 mos , but could be retransformed by the trk oncogene and polyoma virus middle T antigen . ^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| Eight clones , including bFGFR ( xFGFR 1 ) and potential Trk , Ins R . , Fak , Fyn , and Abl homologs , were used to probe temporal and spatial gene expression in early development . ^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| NIH3T3 transformants from a tertiary round of transfection were analysed by Southern blot analysis for the presence of Ki ras , N ras , raf , trk , abl , fms , src , mos , fos , sis , fps , erbA , erbB or neu oncogenes of REC origin , and none were detected . ^^^ |
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| Interacting proteins: P04629 and P00519 |
Pubmed |
SVM Score :0.0 |
| Using the trk , abl and src families of tyrosine kinase encoded proto oncogenes , we discuss here new insights into the structural and functional organization of neural tissues gained from the molecular and genetic analyses of these genes and their products . ^^^ |
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