| Interacting proteins: P42224 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42224 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42224 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42224 and P04626 |
Pubmed |
SVM Score :0.0 |
| In this communication , we report the effects of DDT on c erbB 2 and c met growth factor receptor tyrosine kinase and STATS signal transduction processes in human breast epithelial MCF 10A cells . p , p ' DDT at physiologically relevant concentrations ( i . e . 10 nM ) elevated c erbB 2 , c met and STAT 1 alpha ( p84 / 91 ) tyrosine phosphorylation , stimulated Grb 2 Sos1 association and elevated MAPK phosphorylation . ^^^ |
|
| Interacting proteins: P42224 and P04626 |
Pubmed |
SVM Score :0.0 |
| Immunoblot analysis was performed to detect the proteins corresponding to the highest upregulated genes with cDNA array . mRNA expression of ERBB 2 , KIT , FLT 1 , MYCN , RAS , CDKN2A , CCND 1 , NME 1 , NME 2 , MET , FGF 7 , FGFR 2 , and STAT 1 was increased in malignant samples . ^^^ |
|
| Interacting proteins: P42224 and P04626 |
Pubmed |
SVM Score :0.0 |
| Phosphoproteins that were identified included many known Her 2 signaling molecules as well as known EGFR signaling proteins that had not been previously linked to Her 2 , such as Stat 1 , Dok 1 , and delta catenin . ^^^ |
|