Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
Tyrosine phosphorylation of c ErbB 2 is regulated by the cellular form of prostatic acid phosphatase in human prostate cancer cells . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
Initial studies demonstrate that the androgen responsive phenotype of human prostate cancer cells associates with a low phosphotyrosine ( p Tyr ) level of ErbB 2 , which is regulated by cellular prostatic acid phosphatase ( PAcP ) , a protein tyrosine phosphatase . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
MATERIALS AND METHODS : We evaluated the inherent humoral immune response against prostate specific antigen ( PSA ) , prostatic acid phosphatase , p 53 and HER 2 / neu , all known prostate cancer associated proteins , in 200 patients with various stages of disease and male controls . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
PAC 120 displayed the same immunophenotype of the original tumor ( positive for keratin , vimentin , prostatic acid phosphatase , and Leu 7 ) and expressed human HOXB 9 , HOXA 4 , HER 2 / neu , and prostate specific antigen genes , as detected by reverse transcriptase polymerase chain reaction . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
Tyrosine phosphorylation of ErbB 2 is involved in regulating the androgen responsive phenotype of prostate cancer cells , and it is at least partly regulated by the cellular form of prostatic acid phosphatase ( PAcP ) , a prostate unique protein tyrosine phosphatase . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
Studies on the prostate have shown that ErbB 2 phosphorylation and signaling can be regulated by prostatic acid phosphatase , a histidine acid phosphatase which can dephosphorylate phospho tyrosine residues in the ErbB 2 receptor . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
Although GnRH axon terminals and dendrites contacted VP IR dendrites and NEU cell bodies , we were unable to find convincing examples of GnRH / VP synapses through serial sections , perhaps due to the use of PAP diaminobenzidine as the GnRH ( afferent ) immunolabel . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
By means of potential energy versus distance diagrams , derived from electrophoretic and surface tension data , the minimum distances of approach of normal ( NOR ) and of neuraminidase treated ( NEU ) and papain treated ( PAP ) human erythrocytes could be determined . ^^^ The minimum distances between the actual cell membranes of two opposing red cells are : 184 A ( NOR ) , 111 A ( NEU ) , and 113 A ( PAP ) , which agrees well with the fact that anti D ( Rho ) antibodies of the IgG class ( which have a maximum distance of approximately 120 A between the two antibody active sites ) can hemagglutinate NEU and PAP cells , but are incapable of hemagglutinating normal D ( Rho ) positive erythrocytes . . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
Tissue specimens from 150 patients with localised prostatic carcinomas and 116 patients with prostatic carcinomas with distant metastases were analysed for histological grade ( WHO and Gleason ) and immunoreactivity for prostate acid phosphatase ( PAP ) , prostate specific antigen ( PSA ) , neurone specific enolase ( NSE ) , p 53 protein , c erbB 2 protein , cytokeratins ( AE1 / AE3 ) and vimentin . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
The screening of exposed workers included occupational , medical , and smoking histories to identify exogenous risk factors , a limited physical examination , Papanicolaou ( PAP ) urinary cytology , measurement of urine pH , quantitative fluorescence image analysis ( QFIA ) cytology to detect DNA hyperploidy , and quantitative fluorescence to detect expression of a low grade bladder tumor associated antigen ( p 300 ) by exfoliated urothelial cells and elevated expression of the neu oncogene product ( p 185 ) . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
The expression of c erbB 2 oncoprotein , epidermal growth factor receptor ( EGFR ) and estrogen receptor ( ER ) was evaluated by the immunoperoxidase technique ( PAP ) in ductal breast carcinomas . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
MATERIALS AND METHODS : Th . expression of c erbB 2 and p 53 oncoproteins was evaluated by immunoperoxidase technique ( PAP ) in 62 cases of ductal breast carcinoma . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
We predicted these putative aberrant translation products from the cDNA of three tumor associated antigens ( Ag ) : a transmembrane glycoprotein of the class 1 receptor tyrosine kinase erbB family HER 2 , telomerase reverse transcriptase ( TERT ) and prostatic acid phosphatase ( PAP ) . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
Vitamin D receptor agonists induce prostatic acid phosphatase to reduce cell growth and HER 2 signaling in LNCaP derived human prostate cancer cells . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
Positive expression of c erbB 2 protein in carcinoma tissue was detected in 21 / 56 ( 37 . 5 % ) cases , and the positive rate ( 71 . 4 % ) in tissue of differentiated carcinoma ( pap , tub 1 , tub 2 ) was significantly higher than that in tissue of undifferentiated carcinoma ( por , sig , muc ) ( 28 . 6 % ) . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
Furthermore , there was a positive correlation between PAP activity values and c erbB 2 overexpression but not with its amplification . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
The peroxidase antiperoxidase ( PAP ) method was used for localization of the c erbB 2 oncoprotein at the electron microscopical level in 15 patients with laryngeal squamous cell carcinoma . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
METHODS : Sixty five imprint smears from breast surgical specimens were examined by immunocytochemical staining for c erb B 2 and p 53 and routine pap staining . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
We studied the binding of the peptides from epidermal growth factor receptor ( EGFR ) and its homolog ( ErbB 2 ) , corresponding to their autophosphorylation sites , to PAP using theoretical modeling and molecular dynamics ( MD ) simulation methods . ^^^ Thus we demonstarted that PAP could potentially bind to EGFR and Erbb 2 and dephosphorylate them . ^^^ |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: P15309 and P04626 |
Pubmed |
SVM Score :0.0 |
NA |
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