| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| The macrophage nature of these cells was confirmed by the lack of Thy 1 antigen and immunoglobulins ; the expression of Mac 1 antigen , FcR for IgG , and Ia antigens on their cell surfaces ; their ability to phagocytize EA and adhere to plastic ; the presence of nonspecific esterase and lysomal enzymes in their cytoplasm ; and the pattern of peroxidase localization similar to monocyte derived macrophages . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| SKY BLUE ( 647 nm excitation , 730 nm emission ) fluorospheres conjugated to CD11b monoclonal antibody were used in combination with the monoclonal antibodies IAd FITC , L3T4 ( CD 4 ) PE , LYT 2 ( CD 8 ) APC , THY1 . 2 ( CD 90 ) biotin and B 220 ( CD45R ) RED 613 for the simultaneous detection of six distinct cell surface antigens in a mixed cell population . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| On further phenotypic analysis , these cells co expressed high levels of TCRV beta 8 . 1 / 8 . 2 and CD11b , moderate levels of CD 90 and low levels of CD 4 or CD 8 . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Antigens compared were : mouse spleen CD11b , CD45R , CD 90 ; rat spleen CD11b , CD45RA , Pan T / Ox 52 ; mouse and rat thymus CD 4 , CD8a . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Flow cytometry analysis of isolated pMSCs demonstrated the following phenotype , CD 90 ( pos ) , CD 29 ( pos ) , CD 44 ( pos ) , SLA 1 ( pos ) , CD 106 ( pos ) , CD 46 ( pos ) and CD 45 ( neg ) , CD 14 ( neg ) , CD 31 ( neg ) , and CD11b ( neg ) , similar to that described for human MSC . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| They express CD 59 , CD 90 ( Thy 1 ) , CD 105 , and HLA 1 and were negative for hematopoietic markers such as CD 3 , CD 4 , CD 8 , CD11b , CD 13 , CD 34 , and platelet endothelial cell adhesion molecule 1 ( CD 31 ) . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| In recent studies , the human Thy 1 ( CD 90 ) was characterized as an adhesion molecule on activated endothelial cells ( ECs ) mediating the adhesion of neutrophils via the interaction with the beta 2 integrin Mac 1 . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| T 560 is IgG2a kappa + , Ia+ , B220+ , J11d+ , Thy 1 , CD 3 , CD 4 , CD 5 , Mac 1 , Mac 2 , nonspecific esterase negative and binds bromelain treated mouse RBC but not SRBC or ORBC . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Cultured PBD 1 marrow produced more CD 90 ( br ) MY ( br ) CD 45 ( dim ) CD 4 ( ) MHCII ( ) CD11b ( dim ) eosinophils than did sham . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Cells were isolated by a density gradient ( lymphocytes separation ) and identified by BrdU labeling and fluorescence activated cell sorting ( FACS ) technology using CD11b , CD 45 and CD 90 antibodies . ^^^ Data from FACS showed that about 75 % of isolated cells were CD 90 ( + ) / CD45 ( ) / CD11b ( ) , which is the marker of bone marrow stromal cells . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| The immunodepleted cells expressed the antigens Sca 1 , CD 29 , CD 44 , CD 81 , CD 106 , and the stem cell marker nucleostemin ( NST ) but not CD11b , CD 31 , CD 34 , CD 45 , CD 48 , CD 90 , CD 117 , CD 135 , or the transcription factor Oct 4 . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| After culture , leukocytes were replaced by a homogeneous layer of adherent CD 45 ( ) CD 14 ( ) CD 34 ( ) CD11b ( ) CD 90 ( + ) HLA ABC ( + ) cells . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| The undifferentiated ADAS cells were homogeneously positive for the cell surface markers CD 10 , CD 13 , CD 29 , CD 44 , CD49e , CD 59 , CD 90 , and HLA ABC , and homogeneously negative for the cell surface markers CD11b , CD 45 , and HLA DR . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Flow cytometry analyses showed that they were positive for SH 2 , SH 3 , SH 4 , CD 29 , CD 44 and HLA ABC ( MHC class 1 ) , low positive for CD 90 and CD 105 , but negative for CD 10 , CD11b , CD 14 , CD 34 , CD 117 , HLA DR , DP , DQ ( MHC class 2 ) and EMA . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Here we report this method and reveal the location of early hemopoietic progenitors ( Thy 1 ) and myeloid cells ( Mac 1 ) in mouse BM , and early hemopoietic progenitors and lymphoid cells ( Thy 1 ) , erythroid cells ( HIS 49 ) , and macrophages ( ED 2 ) in rat BM . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Inflammatory cells were rare , as confirmed immunohistochemically ( Thy 1 [ pan T ] , L3T4 [ CD 4 ] , Lyt 2 [ CD 8 ] , interleukin 2 receptor [ activated lymphocyte ] , Mac 1 [ macrophage ] , and B 220 [ pan B ] ) . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Thy 1 , CD 4 , CD 8 , Mac 1 MOMA 1 , MOMA 2 , and Ia antigens were identified on cryostat sections by the immunogold silver staining technique with specific monoclonal antibodies . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Their surface markers were CD45R+ , Ly 1+ , Lyb 2+ , cIgM , sIgM , Ia , Thy 1 , Mac 1 , and IL 2R ( Tac ) + . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| The results of the treatment of the cells to be transferred with monoclonal antibodies and complement show that the cells which is responsible for the transfer of the effect are Mac 1 ( + ) , Thy 1 ( ) , Lyt 2 ( ) and Ia ( ) . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Cells were either labeled directly by exposure to 125I labeled monoclonal antibodies against Thy 1 , Mac 1 , or Lyt antigens or indirectly by a sequential exposure to monoclonal anti 1 Ak ( Ia . 17 ) or monospecific anti 1 JK antibodies and 125I labeled Protein A . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Ig ( ) , Thy 1 ( + ) , L3T4 ( ) , Lyt 2 ( + ) , FcR ( ) , MAC 1 ( ) , and H 2b ( + ) . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| DA 1 expressed MAC 1 , FDC P 1 and DA 3 expressed Thy 1 , and PT 18 ( A 17 ) expressed receptors for the Fc portion of IgE . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Two of the lines examined , S 10 and S 17 , express class 1 histocompatibility antigens but not other hemopoietic cell surface determinants such as Thy 1 , Lyt 1 , Ig , Ia , Mac 1 , or BP 1 . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Surface expression of membrane glycoproteins ( Thy 1 , Lyt 1 , Lyt 2 , L3T4 , IgM , Mac 1 ) was unchanged by the deficiency , as were lymphocyte numbers and distribution . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Type 1 cells express various antigens , including NK 1 , Thy 1 ( 50 % ) , Ly 1 ( 25 % ) , Qa 3 , Qa 4 , Qa 5 , Ly 5 , Ly 6 , Ly 10 , Ly 11 and asialo GM 1 , not expressed by Type 2 cells , whereas Mac 1 may be expressed by both types . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Neither macrophage antigens , such as Mac 1 , Mac 2 , Mac 3 , and F4 / 80 , nor the lymphocyte markers Ly 1 , Ly 2 , and Thy 1 were expressed by FDCs . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Stromal progenitor cells were negative for surface markers Thy 1 and Mac 1 . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| This analysis indicated that cell lines arrested at an early differentiation stage were characterized by the expression of the ' immature ' markers Thy 1 and MIV 113 , and the lack of expression of ' mature ' macrophage markers such as Mac 1 , Mac 2 , and F4 / 80 . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Collagenase dispersed decidua were subjected to total and differential counts and cell surface labeling for a radioautographic identification of various markers : S IgM on B cells , Thy 1 on T cells , neither marker on null lymphocytes , Lyt ( 1 or 2 or 1 , 2 ) antigens on T cell subsets , Mac 1 and 1 A on macrophages , using 125I labeled monoclonal antibodies or a sandwich labeling with 125I protein A . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| They were positive for Ia , Fc receptor , and leukocyte common antigen , but negative for Thy 1 , Ly 1 , Ly 2 , endogenous Ig , Mac 1 , Mac 2 , Mac 3 , and F4 / 80 , and negative to weakly positive for nonspecific esterase . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| For immunohistology we used the immunoperoxidase method and incubated frozen sections of the thymus with 1 ) monoclonal antibodies detecting cell surface differentiation antigens on lymphoid cells , such as Thy 1 , T 200 , Lyt 1 , Lyt 2 , and MEL 14 ; 2 ) monoclonal antibodies detecting the major histocompatibility ( MHC ) antigens , H 2K , 1 A , 1 E , and H 2D ; and 3 ) monoclonal antibodies directed against cell surface antigens associated with cells of the mononuclear phagocyte system , such as Mac 1 , Mac 2 , and Mac 3 . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Extensive studies of surface antigens on cells with NK activity in both mouse and man have led to enigmatic results , such cells apparently bearing markers of both T cell ( Thy 1 and E receptor ) and myeloid ( Mac 1 and OKM 1 ) lineages . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Most clones express Thy 1 , Pgp 1 , ICAM 1 , HSA and B 220 antigen , but are negative for LFA 1 , CD 2 , Mel 14 , Fc receptor , Mac 1 , CD 4 and CD 8 . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Our results demonstrate that whereas expression of major histocompatibility complex ( MHC ) molecules , CD 45 , Mac 1 , LFA 1 , B cell markers , macrophage markers and some T cell markers ( as CD 2 , CD 4 and CD 8 ) did not undergo changes in culture , the level of expression of the adhesion molecules VLA 4 and ICAM 1 , and the T cell markers CD 5 , CD 25 and Thy 1 increased after 14 h incubation at 37 degrees C . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| The surface markers expressed by MTHCs include both granulocyte macrophage lineage specific antigens Gr 1 , 7 / 4 , F4 / 80 , and Mac 1 , as well as two antigens found on early progenitors and stem cells Thy 1 and Sca 1 ( Ly6E ) . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| A subset of cells expresses myeloid macrophage ( Mac 1 and Gr 1 ) , erythroid ( TER 119 ) , and lymphoid ( Thy 1 and B 220 ) lineage markers . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Most TDC were LFA 1 ( CD11a ) + , CD18+ , ICAM 1 ( CD 54 ) + and CD 53 ( OX 44 ) + , but only certain subsets expressed CD11b and thymocyte markers Thy 1 , CD 2 , CD 4 and CD 8 . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Preservation of spatial organization and antigenicity of leukocyte surface molecules by aldehyde fixation : flow cytometry and high resolution FESEM studies of CD62L , CD11b , and Thy 1 . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| All mobilized multipotent progenitor activity was contained in two populations : Thy 1 ( lo ) Sca 1+ Lin Mac 1 CD 4 c kit+ long term reconstituting progenitors and Thy 1 ( lo ) Sca 1+ Lin Mac 1 ( lo ) CD 4 transiently reconstituting progenitors . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| The log of the number of reinfused CD34+ cells , colony forming units granulocyte / macrophage ( CFU GM ) , and CD34+ cells coexpressing VLA 4 , VLA 5 , LAF 1 , Mac 1 , LFA 3 , or CD 38 but not ICAM 1 , Sialyl Lewis ( 10 ) , Sialyl Lewis ( A ) , or Thy 1 correlated with the time required to reach an absolute neutrophil count ( ANC ) of > or =0 . 5 10 10 ( 9 ) / L . ^^^ The log of the number of reinfused CD34+ cells , CFU GM , and CD34+ cells coexpressing CD 44 , L selectin , VLA 5 Mac 1 , or CD 38 , but not VLA 4 , LAF 1 , ICAM 1 , LAF 3 , Sialyl Lewis ( 10 ) , Sialyl Lewis ( A ) , or Thy 1 , correlated with the time required to reach a platelet count of > 20 10 10 ( 9 ) / L . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| However , at 10 months after nerve grafting there were fewer Mac 1 , Lyt 1 , and Thy 1 positive cells in the five day group and they showed less immunoreactivity than the untreated group . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Examination of leukocyte cell surface antigens expressed by splenocytes revealed no statistically significant changes in the level of the T lymphoid antigens Thy 1 , CD 5 , CD 4 , CD 8 and CD 3 , the macrophage antigen Mac 1 , and the adhesion molecules LFA 1alpha , LFA 1beta and L Selectin , following GM CSF immunostimulation . ^^^ In parallel , immunohistochemical analysis of the uteroplacental unit revealed Mac 1 and to a lesser extent LFA 1beta positive cells localized to the myometrium and the placenta in both the control and the GM CSF treated groups , while no cells expressing Thy 1 , CD 3 , CD 4 , CD 8 , or LFA 1alpha could be demonstrated . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Using intracellular TSH staining and enzyme linked immunoassay for detection of secreted TSH , we demonstrate that TSH synthesis in BM cells occurs within CD 45 ( + ) ( leukocyte common antigen ) hematopoietic cells and that the majority of that activity resides in a component of CD11b ( + ) BM cells that are not mature T cells , B cells , or Thy 1 ( + ) cells in the BM . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| Their phenotypes , determined by depletion of cell transfers by mAb and complement , are CD 5 ( + ) , CD 19 ( + ) , CD 22 ( + ) , B 220 ( + ) , Thy 1 ( + ) , and Mac 1 ( + ) , suggesting that they are B 1 B cells . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| The pMSCs isolated from bone marrow grew , attached to plastic with a fibroblast like morphology , and expressed the mesenchymal surface marker THY 1 but not the hematopoietic marker ITGAM . ^^^ |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04216 and P11215 |
Pubmed |
SVM Score :0.0 |
| NA |
|