| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.66143659 |
| Significant amounts of plasmin were generated from the TSP HRGP Plg complex ( equivalent to that from the TSP Plg complex ) , but the rate of plasmin generation from the trimolecular complex was greater than from the bimolecular complex , suggesting an important interaction of HRGP with Plg when both are complexed to TSP . 0.66143659^^^ |
|
| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.68360661 |
| We have shown previously that HRGP binds with high affinity to thrombospondin 1 ( TSP 1 ) , a homotrimeric glycoprotein that is a potent inhibitor of angiogenesis . 0.68360661^^^ |
|
| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.0 |
| Plg activators did not influence binding of Plg to histidine rich glycoprotein or of histidine rich glycoprotein to TSP , demonstrating specificity . ^^^ |
|
| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.0 |
| Ternary complex formation of tissue plasminogen activator ( TPA ) and plasminogen ( Plg ) with thrombospondin ( TSP ) or histidine rich glycoprotein ( HRGP ) has been demonstrated using an enzyme linked immunosorbent assay , an affinity bead assay , and a rocket immunoelectrophoresis assay . ^^^ |
|
| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.0 |
| Thrombospondin ( TSP ) , a multifunctional alpha granule glycoprotein of platelets , binds fibrinogen , fibronectin , heparin , and histidine rich glycoprotein and thus may play an important role in regulating thrombotic influences at vessel surfaces . ^^^ |
|
| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.0 |
| We conclude that TSP 1 contains a high affinity binding site for polyhistidine and this is likely to be the molecular basis for the observed binding of TSP 1 to histidine rich glycoprotein . ^^^ |
|
| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.0 |
| This 93 120 amino acid region , previously identified as the TSP 1 binding site , is homologous to domains on other TSP binding proteins , such as LIMP 2 and histidine rich glycoprotein ( HRGP ) . ^^^ |
|
| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.0 |
| Many of them , including thrombospondin 1 ( TSP 1 ) , histidine rich glycoprotein , kininogen 1 , and alpha 2 macroglobulin ( alpha2M ) , are well known glycoproteins involved in the regulation of inflammation , angiogenesis , and tissue remodeling . ^^^ |
|
| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P07996 |
Pubmed |
SVM Score :0.0 |
| NA |
|