| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.75418997 |
| The association of plasma histidine proline rich glycoprotein ( HPRG ) with plasminogen ( PLG ) was examined using a sucrose density gradient assay in order to evaluate the effects of several relevant conditions on complex formation . 0.75418997^^^ Interaction of histidine proline rich glycoprotein with plasminogen : effect of ligands , pH , ionic strength , and chemical modification . 0.50130118^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :1.2310029 |
| Importantly , plasminogen interacted specifically with GAG bound HPRG . 1.2310029^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.64235134 |
| L Asparaginase therapy reduced plasma levels of plasminogen and histidine rich glycoprotein ( HRG ) and influenced the equilibrium between HRG , plasminogen and HRG plasminogen complex , with a more pronounced decrease of plasminogen ( 62 % + / 8 ) and HRG ( 76 % + / 11 ) in comparison to the free plasminogen levels ( 51 % + / 6 ) . alpha 2 Macroglobulin was only slightly influenced by L asparaginase and may consequently play a more pronounced role in inhibition . 0.64235134^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Acceleration of plasminogen activation by tissue plasminogen activator on surface bound histidine proline rich glycoprotein . ^^^ Histidine proline rich glycoprotein ( HPRG ) , also known as histidine rich glycoprotein , is a major plasminogen binding protein . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Effects of histidine proline rich glycoprotein on plasminogen activation in solution and on surfaces . ^^^ Histidine proline rich glycoprotein ( HPRG ) has long been known to associate with plasminogen ( Plg ) in solution , but the consequences of this interaction have not been defined . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| The efficacy of this system can be evaluated by plasminogen concentration determinations and by the behavior of factors such as histidine rich glycoprotein ( HRG ) which controls plasminogen activation and alpha 2 antiplasmin which controls plasmin activity . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Plasminogen binding by alpha 2 antiplasmin and histidine rich glycoprotein does not inhibit plasminogen activation at the surface of fibrin . alpha 2 antiplasmin ( alpha 2 AP ) exerts its inhibitory effect on fibrinolysis by rapidly inhibiting the plasmin evolved ; in addition , it has been suggested that interference with the binding of plasminogen to fibrin , a function shared with histidine rich glycoprotein ( HRGP ) , may also be significant in inhibition of fibrinolysis . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| The process is regulated by physiological inhibitors , of which alpha 2 antiplasmin , histidine rich glycoprotein and plasminogen activator inhibitor are reported to be of major physiological significance . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| A similar effect was also apparent in the corresponding euglobulin fractions ( 554 + / 169 fmol versus 754 + / 310 fmol ) , the latter lacking the plasminogen binding proteins alpha 2 antiplasmin and histidine rich glycoprotein , but containing Lp ( a ) . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| The plasma concentrations of histidine rich glycoprotein and plasminogen were measured and those of free plasminogen calculated in 34 patients with acute myocardial infarction treated with thrombolytic drugs . ^^^ We investigated whether the plasma levels of histidine rich glycoprotein and free plasminogen were associated with clinical parameters such as the occurrence and time of successful reperfusion , the incidence of reocclusion and the presence and extent of the systemic lytic state . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| In fetuses , euglobulin clot lysis time ( ECLT ) was significantly shortened , plasminogen level was low and histidine rich glycoprotein undetectable . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| The most marked differences between malignant tumors and controls were elevated plasma levels of tissue plasminogen activator antigen ( P less than 0 . 005 ) , plasminogen activator inhibitor ( P less than 0 . 01 ) , cross linked fibrin degradation products ( P less than 0 . 001 ) , fragment B beta 15 42 ( P less than 0 . 001 ) and histidine rich glycoprotein ( P less than 0 . 005 ) . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Significant changes occur in the concentrations of platelets and white blood cells , hematocrit ( Ht ) , von Willebrand factor antigen ( vWF : ag ) , antithrombin 3 activity ( AT 3 ag ) , antithrombin 3 antigen ( AT 3 ant ) , fibrinogen , plasminogen , alpha 2 antiplasmin ( alpha 2 AP ) , histidine rich glycoprotein ( HRG ) , and plasminogen activator inhibitor ( PAI ) activity . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| A plasminogen binding protein ( histidine rich glycoprotein ) , plasmin inhibitors and activator inhibitors appear to contribute to the regulation of the initial phase of fibrinolysis . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| We have found that low dose oral contraceptives containing levonorgestrel or lynestrenol enhance fibrinolysis , as revealed by an increase in plasminogen ( 30 % to 40 % ) , a decrease in histidine rich glycoprotein ( 15 % to 26 % ) , an increase in tissue plasminogen activator activity ( greater than 150 % ) , and a decrease in tissue plasminogen activator inhibition ( 30 % to 40 % ) , concomitant with a slight decrease in tissue plasminogen activator antigen level ( 15 % to 20 % ) . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Histidine rich glycoprotein and plasminogen plasma levels in term and preterm newborns . ^^^ Histidine rich glycoprotein ( HRG ) , another fibrinolytic inhibitor , retards fibrinolysis by interfering with plasminogen ' s binding to fibrin . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Thrombospondin interacts with heparin , fibrinogen , fibronectin , collagen , histidine rich glycoprotein , and plasminogen . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| In competitive radioimmunoassays the binding of radiolabeled plasminogen to MA HAL was reduced to 50 % with 2 . 3 microM alpha 2 antiplasmin or 1 . 3 microM histidine rich glycoprotein , which corresponds to the known dissociation constants between these ligands and the high affinity lysine binding site of plasminogen . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Plg activators did not influence binding of Plg to histidine rich glycoprotein or of histidine rich glycoprotein to TSP , demonstrating specificity . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Ternary complex formation of tissue plasminogen activator ( TPA ) and plasminogen ( Plg ) with thrombospondin ( TSP ) or histidine rich glycoprotein ( HRGP ) has been demonstrated using an enzyme linked immunosorbent assay , an affinity bead assay , and a rocket immunoelectrophoresis assay . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Less frequent and / or less established causes are low heparin cofactor 2 and plasminogen and high levels of plasminogen activator inhibitor and histidine rich glycoprotein . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| However , free plasminogen not bound to histidine rich glycoprotein was not significantly different between these two groups . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| There were no significant differences between the groups in plasma concentrations of plasminogen , histidine rich glycoprotein , plasminogen kringle 4 binding protein , and alpha 2 antiplasmin . . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Binding of thrombospondin to immobilized ligands : specific interaction with fibrinogen , plasminogen , histidine rich glycoprotein , and fibronectin . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| The rate of activation of plasminogen by pro UK is not significantly influenced by the presence of 6 aminohexanoic acid , purified fragments LBS 1 or LBS 2 or histidine rich glycoprotein , indicating that the high affinity of pro UK for plasminogen is not mediated via the high affinity lysine binding site of plasminogen located in kringles 1 3 ( LBS 1 ) nor via the low affinity lysine binding site comprised within kringle 4 ( LBS 2 ) . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Platelet thrombospondin forms a trimolecular complex with plasminogen and histidine rich glycoprotein . ^^^ Thrombospondin ( TSP ) , a multifunctional alpha granule glycoprotein of human platelets binds fibrinogen , fibronectin , heparin , histidine rich glycoprotein ( HRGP ) , and plasminogen ( Plg ) , and thus , may play an important role in regulating thrombotic influences at vessel surfaces . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Although the biological function of histidine rich glycoprotein ( HRG ) is unknown , it may serve as an antifibrinolytic agent by interfering with the binding of plasminogen to fibrin . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Plasma histidine rich glycoprotein and plasminogen in patients with liver disease . ^^^ Histidine rich glycoprotein ( HRG ) has been reported to be a fibrinolysis regulating protein due to its capacity to bind to the high affinity lysine binding sites of plasminogen . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Although fibrinogen , plasminogen , and alpha 2 antiplasmin were present in culture supernatants , histidine rich glycoprotein was not detected . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Histidine rich glycoprotein , and alpha 2 glycoprotein in human plasma , has been shown to interact with heparin , with the high affinity lysine binding site of plasminogen , with divalent cations , and is associated with the rosette formation between erythrocytes and lymphocytes . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Histidine rich glycoprotein and alpha 2 plasmin inhibitor in inhibition of plasminogen binding to fibrin . ^^^ The plasma proteins alpha 2 plasmin inhibitor and histidine rich glycoprotein were compared directly with respect to their effectiveness in inhibiting the binding of plasminogen to fibrin under the same experimental conditions . ^^^ At their physiological concentrations , the presence of alpha 2 plasmin inhibitor more markedly decreased the binding of plasminogen to fibrin than histidine rich glycoprotein . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| A sequential study of plasma histidine rich glycoprotein and plasminogen in patients with acute myocardial infarction and deep vein thrombosis . ^^^ In a prospective study of deep vein thrombosis ( DVT ) , detected by the Tc plasmin test , in 34 patients with acute myocardial infarction sequential determinations were made in plasma by immunologic methods of histidine rich glycoprotein ( HRG ) and total plasminogen and the concentrations of free plasminogen calculated . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| This was associated with significant increases in plasma plasminogen and a concomitant reduction in histidine rich glycoprotein . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| The predisposing and triggering factors of thrombosis have been carefully recorded and a study of hemostasis parameters has been performed , including AT 3 determination , fibrinolytic activity before and after venous occlusion , plasminogen , alpha 2 antiplasmin and histidine rich glycoprotein determination . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Decreased levels of histidine rich glycoprotein ( HRG ) and increased levels of free plasminogen in women on oral contraceptives low in estrogen . ^^^ Determinations by immunologic methods of histidine rich glycoprotein ( HRG ) and plasminogen , were made in plasma samples collected during one normal or hormone induced cycle in 15 young , normal women and in 11 women using oral contraceptives with 30 micrograms ethinyl estradiol and 150 micrograms levo norgestrel . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Plasma levels of plasminogen and histidine rich glycoprotein ( HRG ) increased and decreased , respectively , whereas an increase in von Willebrand factor was observed in the treatment group . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| It is not clear whether loss of endogenous ovarian steroid production or the effects of the orally administered contraceptive steroids cause significant changes in hemostatic factors ( antithrombin 3 , protein S , protein C , plasminogen , tissue type plasminogen activator , plasminogen activator inhibitor 1 , histidine rich glycoprotein , and 7 , 8 , 10 , 12 coagulation factors ) during OC use . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| The binding of plasminogen to fibrin is regulated by histidine rich glycoprotein , and the primary physiological inhibitor of generated plasmin is alpha 2 antiplasmin and especially the plasminogen binding form of this immediate plasmin inhibitor . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| A month after stopping the drug , her plasma activities of antithrombin 3 , protein C , protein S , heparin cofactor 2 , plasminogen and plasminogen activator inhibitor were normal , but her plasma histidine rich glycoprotein ( HRG ) level was only 21 % of the normal level of 109 . 5 + / 51 . 5 % ( mean + / 2 SD ) . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Histidine rich glycoprotein ( HRGP ) has been believed to have anti fibrinolytic activity through its binding to plasminogen . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Anabolic steroids increase the activity of the fibrinolytic system by reducing plasma levels of inhibitors ( plasminogen activator inhibitor type 1 , histidine rich glycoprotein , alpha 2 macroglobulin ) and increasing plasma levels of tissue type plasminogen activator activity , plasminogen , and plasmin activity ( B beta 15 42 fragment of fibrinogen ) . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| A recent report suggests that histidine rich glycoprotein binds to the high affinity lysine binding sites of plasminogen and that histidine rich glycoprotein may retard fibrinolysis by interfering with the binding of plasminogen to fibrin [ 3 ] . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Plasminogen activity and antigen , euglobulin fibrinolytic activity , tissue type plasminogen activator activity and antigen urokinase type plasminogen activator antigen , plasminogen activator inhibitor 1 activity and antigen , plasminogen activator inhibitor 2 antigen , tissue type plasminogen activator / plasminogen activator inhibitor complexes , alpha 2 antiplasmin , histidine rich glycoprotein , and fibrinogen / fibrin degradation products were measured in blood samples taken from the umbilical vein of 100 healthy full term newborns . ^^^ There was a significant reduction in plasminogen activity and antigen ( P < 0 . 0001 ) , plasminogen activator inhibitor 1 activity ( P < 0 . 05 ) , alpha 2 antiplasmin ( P < 0 . 0001 ) , and histidine rich glycoprotein ( P < 0 . 0001 ) , whereas plasminogen activator inhibitor 2 , tissue type plasminogen activator / plasminogen activator inhibitor complexes and fibrinogen / fibrin degradation products did not differ between groups . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| The DHG column strongly bound factor 5 , factor 9 , protein S , histidine rich glycoprotein , platelet factor 4 ( PF 4 ) , beta thromboglobulin , von Willebrand factor , fibronectin , and heparin cofactor 2 , but did not bind fibrinogen , prothrombin , factor 7 , protein C , antithrombin 3 ( ATIII ) , plasminogen or alpha 2 plasmin inhibitor . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Abnormalities of the fibrinolytic system were also reported , such as increased levels of both tissue type plasminogen activator and type 1 plasminogen activator inhibitor or decreased levels of histidine rich glycoprotein . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| P 123 did not cross link to plasminogen , histidine rich glycoprotein , fibronectin , or plasma globulins other than fibrinogen / fibrin . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Because histidine rich glycoprotein binds to the kringle 1 3 domain of plasminogen , it may affect fibrinolysis by reducing fibrin dependent plasmin production , and in this way it could be mechanistically analogous to 6 aminohexanoic acid . ^^^ We tested this hypothesis by comparing the effects of histidine rich glycoprotein and 6 aminohexanoic acid in an in vitro assay of fibrin dependent plasmin production mediated by tissue plasminogen activator . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Familial association of high levels of histidine rich glycoprotein and plasminogen activator inhibitor 1 with venous thromboembolism . ^^^ High levels of histidine rich glycoprotein ( HRGP ) and plasminogen activator inhibitor 1 ( PAI 1 ) have been claimed to contribute to the hypofibrinolytic state observed in patients with venous thrombosis . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| However , by immunoprecipitation of relatively undiluted serum with anti HRG IgG beads , HRG was found to coprecipitate with S protein and plasminogen , which suggested that HRG may complex with these proteins in serum . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Levels of both HRG and plasminogen were higher in the stressed group but the ratio of HRG to plasminogen was the same as that in the normal control newborns ( 1 : 3 ) , suggesting an insignificant effect of HRG . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| The genes considered are ; alpha fibrinogen , beta fibrinogen , gamma fibrinogen , prothrombin , tissue factor , factor 5 , protein S , complement component 4 binding protein , factor 11 , factor 12 , factor XIIIa , factor XIIIb , histidine rich glycoprotein , high molecular weight kininogen , kallikrein , von Willebrands factor , platelet factor 4 , thrombospondin , antithrombin 3 , alpha 1 antitrypsin , thrombomodulin , plasminogen , tissue plasminogen activator , urokinase plasminogen activator , plasminogen activator inhibitor 1 , plasminogen activator inhibitor 2 , protein C inhibitor , alpha 2 plasmin inhibitor , kallistatin , lipoprotein a , interleukin 6 , interleukin 1 , cystathionine beta synthase , and methylenetetrahydrofolate reductase . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Plasminogen is tethered with high affinity to the cell surface by the plasma protein , histidine rich glycoprotein . ^^^ Previous studies have reported that the plasma protein , histidine rich glycoprotein ( HRG ) , interacts with plasminogen and cell surfaces , raising the possibility that HRG may immobilize plasminogen / plasmin to cell surfaces . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Binding of inhibitors such as alpha 2 antiplasmin , plasminogen activator inhibitor 2 , lipoprotein ( a ) , or histidine rich glycoprotein , impairs plasminogen activation . ( 4 ) Enhanced interactions with the extracellular matrix by binding of fibronectin to fibrin ( ogen ) . ( 5 ) Molecular and cellular interactions of fibrin beta 15 42 . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Previous studies have shown that histidine rich glycoprotein ( HRG ) , an abundant ( approximately 100 microg / ml ) 75 kDa plasma glycoprotein , binds to cell surface heparan sulfate on viable cells and cross links other ligands , such as plasminogen , to the cell surface . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| XII ( n = 3 ) , plasminogen ( n = 2 ) , HCII ( n = 1 ) , increased HRGP ( n = 4 ) ; new candidate risk factors for thrombophilia : elevated plasma levels of Lp ( a ) ( n = 26 ) , F . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| To study the reversible complex formation between the plasma protein histidine rich glycoprotein ( HRG ) and plasminogen , crossed immunoelectrophoresis of HRG was modified . ^^^ Two molecular forms of plasminogen , Glu and Lys plasminogen , induced a dose dependent reduction of the electrophoretic mobility of HRG , with a half maximal retardation for both plasminogens at 0 . 50 0 . 55 microM of added plasminogen to the agarose gel . ^^^ HRG in plasma behaved as a uniform fraction with respect to plasminogen binding . ^^^ The method can be used to assess several aspects of reversible complex formation between plasma proteins , as demonstrated for plasminogen binding of HRG and alpha 2 antiplasmin in whole plasma . . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Histidine rich glycoprotein ( HRG ) reduces by complex formation with plasminogen the amount of `` free ' ' plasminogen in circulation and is therefore considered an inhibitor of fibrinolysis . ^^^ We studied the levels of both HRG and plasminogen in patients with different degrees of liver cirrhosis to assess the role of HRG in enhanced fibrinolysis in these patients . ^^^ In moderate ( Child B ) cirrhosis , both HRG levels and total plasminogen levels were reduced , resulting in a normal amount of free plasminogen in circulation . ^^^ In severe ( Child C ) cirrhosis , HRG level , total plasminogen level , and free plasminogen level were all decreased . ^^^ Because of the reduction of free plasminogen levels in severe liver cirrhosis , we propose that the decrease in HRG levels in liver cirrhosis plays no role in enhanced fibrinolysis in these patients . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| The binding of this variant HRG to plasminogen was normal . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| HRG and PGE 2 each induced the formation of well organized , three dimensional structures with empty spaces in the center and stimulated the expression of urokinase plasminogen activator ( uPA ) with differential localization of membrane bound uPA at the focal adhesion points and leading edges of the motile cells . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| HRG ligands include Zn ( 2+ ) and haem , tropomyosin , heparin and heparan sulphate , plasminogen , plasmin , fibrinogen , thrombospondin , IgG , FcgammaR and complement . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| In normal volunteers , HRGP levels did not correlate with either plasminogen contents or plasminogen activity , although HRGP has been believed to be a modulator for fibrinolysis system . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Histidine rich glycoprotein ( HRGP ) , a human plasma and platelet protein , interacts with multiple ligands in vitro , including heparin , plasminogen , thrombospondin , and fibrinogen / fibrin . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| Prothrombotic disorders were found in 8 out of 26 patients with cerebral infarction ( FV Leiden mutation : n = 4 ; protein C deficiency : n = 1 ; FV Leiden mutation + protein C deficiency : n = 2 ; prothrombin mutation G20210A : n = 1 ) and in 13 out of 17 with venous thrombosis ( FV Leiden mutation n = 3 ; protein C deficiency n = 5 ; elevated HRGP + PAI : n = 1 , combined deficiency of AT , protein C and plasminogen : n = 1 ; F 12 deficiency : n = 1 ; lupus anticoagulans n = 1 ; FV Leiden + F 12 deficiency + lupus anticoagulans + PAI : n = 1 ) . ^^^ |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04196 and P00747 |
Pubmed |
SVM Score :0.0 |
| NA |
|