| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| Dehydration also induced an increase in adenopituitary POMC ( C ) and PC 1 ( FR 50 ) , PVN and SON VP ( C ) and GR in CA 1 hippocampal area ( FR 50 ) mRNA levels and plasma ACTH ( C ) , but a decrease in MR in DG ( C ) and GR in CA 3 and DG ( C ) mRNA levels . ^^^ |
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| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| In the adenohypophysis , GR and prohormone convertase 2 ( PC 2 ) mRNA levels were significantly increased , whereas prohormone convertase 1 ( PC 1 ) mRNA was not affected by maternal undernutrition . ^^^ |
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| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| Small ubiquitin related modifier 1 ( SUMO 1 ) modification of the glucocorticoid receptor . ^^^ Small ubiquitin related modifier 1 ( SUMO 1 ) modification of the glucocorticoid receptor . ^^^ The SUMO 1 conjugating E 2 enzyme Ubc 9 is known to interact with the glucocorticoid receptor ( GR ) , a ligand dependent transcription factor . ^^^ |
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| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| NII were immunoreactive for ubiquitin , glucocorticoid receptor , and SUMO 1 , a small , ubiquitin like protein purportedly involved in protein transport and gene transcription . ^^^ |
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| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| With high concentrations of GR , added Ubc 9 also reduces the EC ( 50 ) of agonists and increases the partial agonist activity of antagonists in a manner that is independent of the ability of Ubc 9 to transfer SUMO 1 ( small ubiquitin like modifier 1 ) to proteins . ^^^ |
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| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| We showed that the GR is covalently modified by the small ubiquitin related modifier 1 ( SUMO 1 ) peptide in mammalian cells . ^^^ SUMO 1 overexpression induces dramatic GR degradation , abolished by proteasome inhibition . ^^^ Overexpression of SUMO 1 specifically enhances the ligand induced transactivation of GR up to 8 fold . ^^^ We propose a model in which SUMO 1 regulates the synergy control function of GR and serves as a unique signal for activation and destruction . . ^^^ |
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| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P04150 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|