| Interacting proteins: P15036 and P04150 |
Pubmed |
SVM Score :0.0 |
| Physical interaction and functional synergy between glucocorticoid receptor and Ets 2 proteins for transcription activation of the rat cytochrome P 450c27 promoter . ^^^ We demonstrate that dexamethasone mediated transcription activation of the cytochrome P 450c27 promoter involves a physical interaction and functional synergy between glucocorticoid receptor ( GR ) and Ets 2 factor . ^^^ Ets 2 protein binding to a `` weak ' ' Ets like site of the promoter is dependent on GR bound to the adjacent cryptic glucocorticoid response element . ^^^ Coimmunoprecipitation and chemical cross linking experiments show physical interaction between GR and Ets 2 proteins . ^^^ Mutational analyses show synergistic effects of Ets 2 and GR in dexamethasone mediated activation of the cytochrome P 450c27 promoter . ^^^ |
|
| Interacting proteins: P15036 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15036 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|