| Interacting proteins: O43294 and P04150 |
Pubmed |
SVM Score :0.0 |
| Interaction of the tau 2 transcriptional activation domain of glucocorticoid receptor with a novel steroid receptor coactivator , Hic 5 , which localizes to both focal adhesions and the nuclear matrix . ^^^ In the present study , a yeast two hybrid screen identified Hic 5 as a protein that interacts with a region of the glucocorticoid receptor that includes a nuclear matrix targeting signal and the tau 2 transcriptional activation domain . ^^^ The C terminal region of Hic 5 , which contains seven zinc fingers arranged in four LIM domains , was required for interaction with focal adhesions , the nuclear matrix , steroid receptors , and the tau 2 domain of glucocorticoid receptor . ^^^ |
|
| Interacting proteins: O43294 and P04150 |
Pubmed |
SVM Score :0.0 |
| ERK 8 down regulates transactivation of the glucocorticoid receptor through Hic 5 . ^^^ One binding partner identified was Hic 5 ( also known as ARA 55 ) , a multiple LIM domain containing protein implicated in focal adhesion signaling and the regulation of specific nuclear receptors , including the androgen receptor and the glucocorticoid receptor ( GR ) . ^^^ |
|
| Interacting proteins: O43294 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O43294 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|